Highlighted Publications - June 2025

Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics:

• Evolutionary and Population Genetics
• Genome Structure and Function
• Molecular Basis of Mendelian Disorders
• Complex Traits and Diseases
• Developmental Genetics

Michigan Experts is a searchable database of research expertise across disciplines from several schools/colleges or institutes at the University of Michigan. Please explore The Department of Human Genetics' research profile and collaboration network on the Michigan Experts website.

PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites. 

Cross-Ancestry Associations of Spontaneous Coronary Artery Dissection Genetic Risk With Coronary Atherosclerosis and Migraine Headache

Xu C, Yang ML, Kho PF, Clarke SL, Tcheandjieu C, Peyser PA, Fann CS, Chen SP; VA Million Veteran Program; Saw J, Zhou X, Assimes TL, Ganesh SK. Cross-Ancestry Associations of Spontaneous Coronary Artery Dissection Genetic Risk With Coronary Atherosclerosis and Migraine Headache. J Am Heart Assoc. 2025 May 20;14(10):e036525. doi: 10.1161/JAHA.124.036525. Epub 2025 May 13. PMID: 40357661.

https://pubmed.ncbi.nlm.nih.gov/40357661/

Collaborators:

• Santhi K Ganesh

A zinc finger-dependent, PRDM13-driven mechanism regulates retinal progenitor cell fate from mouse embryonic stem cells via WNT signaling

Basinski BW, Huang Y, Li Q, Sivakumar CD, Carman TJ, Pan HM, Xu J, Hannum DF, Liu J, Rao RC. A zinc finger-dependent, PRDM13-driven mechanism regulates retinal progenitor cell fate from mouse embryonic stem cells via WNT signaling. Stem Cell Reports. 2025 May 19:102508. doi: 10.1016/j.stemcr.2025.102508. Epub ahead of print. PMID: 40409260.

https://pubmed.ncbi.nlm.nih.gov/40409260/

Collaborators:

• Rajesh Rao

Ribosome association inhibits stress-induced gene mRNA localization to stress granules

Helton NS, Dodd B, Moon SL. Ribosome association inhibits stress-induced gene mRNA localization to stress granules. Genes Dev. 2025 Jul 1;39(13-14):826-848. doi: 10.1101/gad.352899.125. PubMed [citation] PMID: 40360199, PMCID: PMC12212004.

https://pubmed.ncbi.nlm.nih.gov/40360199/

Collaborators:

• Noah Helton
• Ben Dodd
• Stephanie Moon

Please explore the Department of Human Genetics' publications on the PubMed Central website.