Research Drives Discovery

As one of the most powerful academic medical research engines in the country, the University of Michigan Medical School empowers our scientists and clinicians to work together to transform the biggest challenges in biomedicine into breakthroughs in patient care.

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Birdseye view of North Campus Research Complex
Research is the Reason

Groundbreaking discoveries that happen daily at the University of Michigan Medical School are made possible by our unique system of collaboration and innovation. We bring together expert researchers, clinicians and clinician-scientists across disciplines and provide them the tools, training and funding they need to make connections that are crucial to medical breakthroughs.

Nothing is Out of Reach
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Labs & Departments

Learn about the labs that are at the heart of our research work and their integration with our clinical and basic science departments.

Office of Research

The U-M Medical School Office of Research is constantly striving to enhance the research enterprise through maintaining an investigator-focused infrastructure and streamlining research processes.

Research & Innovation

Discover our areas of research, fueled by over half a billion dollars of funding each year of that is awarded to the U-M Medical School.

Research & Innovation
Changing the Future of Health Care

Patient needs are constantly evolving, impacting the future of health care. Now more than ever, it's vital to empower diverse approaches to science and medicine. Through the U-M Medical School's interconnected research areas, we bring together experts from an array of fields to collaborate, innovate and make discoveries that transform patient lives.

Discover our Strategic Research Initiatives
Join Us in Shaping the Future of Medicine
175th Anniversary

This year, we celebrate 175 years of shaping medical and scientific leaders, advancing discovery and innovation, and caring for the people of Michigan and beyond. Discover more about our history.

Celebrate our 175th
News & Stories More Research News covid signs out in city
Health Lab
COVID-19 is the latest epidemic to show biomedical breakthroughs aren’t enough to eliminate a disease
An infectious disease doctor and medical historian details similarities to other epidemics such as syphilis, AIDS and tuberculosis.
sperm moving to cell all blue and cell red
Health Lab
Battle of the sex chromosomes
A study from University of Michigan researchers has uncovered the mechanism behind the arms race for mouse X and Y bearing sperm to fertilize an egg.
drawing of blood monitor on person
Health Lab
Continuous glucose monitors can optimize diabetic ketoacidosis management
University of Michigan researchers show that using continuous glucose monitors can help measure glucose accurately during DKA and potentially prevent ICUs from being overwhelmed.
Well-Being at Michigan Medicine podcast - a part of the Michigan Medicine Podcast Network.
Well-Being at Michigan Medicine
Who are we? Meet the Office of Well-Being team
This special installment of Well-Being at Michigan Medicine coincides with celebrating Health Workforce Well-Being Day on March 18, 2025. As such, this episode brings together Chief Well-Being Officer Elizabeth Harry, M.D., and Jeffrey Patterson, M.H.S.A., M.P.H., the senior director for well-being operations and strategy. The duo discusses the evolution of the Office of Well-Being from its past iteration and how it brings a broader focus on creating environments where individuals and teams thrive, emphasizing well-being and addressing upstream factors that lead to burnout. Additionally, Dr. Harry and Patterson chat about key tenants of their work: operational well-being, culture of well-being and personal resilience. Recently, the team has grown, and new members have brought greater expertise to the organization. Learn more about how the Office of Well-Being aids it team members and brings a culture of belonging, resilience and support.
xray brain images on repeat and person pointing with pointer
Health Lab
Re-purposed FDA-approved drug could help treat high-grade glioma
Avapritinib, an FDA-approved drug used to treat other types of cancer, also decreases aggressive gliomas in animal models and in an initial cohort of patients with high-grade glioma.
red rash on elbow
Health Lab
Study doubles number of genetic signals for psoriasis
A large genome wide association study (GWAS) of psoriasis identifies new susceptibility variants that underlie this common, yet enigmatic, skin disease.
Research Events View more research events
Introduction to sIRBs
This course will identify the Single IRB model for Multi-Site research, show the regulatory requirements of sIRB review and the exceptions to sIRB requirements, and explain sIRB requests of IRBMED as sIRB (accepting oversight), External IRB as sIRB (ceding oversight), and UofM as the Coordinating Center.
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FDA Research Involving Drugs and Devices
This course will review what research is subject to FDA oversight, highlight the differences between OHRP and FDA regulations, learn the responsibilities of sponsors, investigators, and the IRB when conducting and reviewing research involving drugs and devices, and examine the requirements for conducting research with a drug or biologic/medical device.
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Not Regulated, Secondary Use, and Umbrella Applications
This course will review the Not Regulated, Secondary Use, and Umbrella application types in eResearch and when these application types are applicable.
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OHRP’s Subparts B, C, and D -Special Populations
This course will examine the additional regulatory requirements for conducting research involving pregnant women, fetuses, neonates, children, and prisoners, including the requirements for these populations in a research project and obtaining informed consent.
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BRCF Transgenic Animal Model Core: QC + genotyping: Validate what you made is what you think it is!
Join the BRCF Transgenic Animal Model Core for a complimentary lunch and learn how to validate your model.
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Flow and Cookies at NCRC
Help yourself to a cookie and learn how the Flow Cytometry Core can enhance your research. Core experts will speak about services and instrumentation capabilities.
Event runs February 28, 2025 - April 25, 2025
Federal and Institutional Requirements for Human Subject Research
This course will introduce the basics of conducting human subject research in compliance with federal regulations and institutional practices.
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Short Read Sequencing: An AGC Workshop
This virtual workshop covers how to work with the AGC for bulk RNA, DNA, and protein analysis using Illumina or Singular Genomics instruments. Topics include input requirements, selecting the right library prep and sequencing platform, experimental design considerations, calculating cost estimates, and deliverables.
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Spatial Analysis: An AGC Workshop
This virtual workshop covers how to work with the AGC for spatial analysis using Visium/CytAssist, Xenium, Curio Seeker, Curio Trekker, and Aviti24. Topics include selecting the correct platform, input requirements, experimental design considerations, calculating cost estimates, and deliverables.
Two people in an office during a data consultation