Biomedical Research Core Facilities

We believe in serving you, advancing health, and paving the way for great discoveries in biomedical research at the University of Michigan and beyond.

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Spotlight On

Nanoparticles genetically modify several human cell types

The protein nanoparticles could help doctors treat cancer and genetic diseases without using modified viruses, which sometimes have harmful side effects. The nanoparticles were studied, in part, at the BRCF Microscopy Core.

How We Serve Your Biomedical Research Needs

The BRCF centralized access to research services, shared equipment, and the expertise of biomedical researchers/investigators to support research projects. Explore our Careers, FAQs, and Mission here.

More About Us
A BRCF Research Store staff member hands a product to a customer.

Essential Research Materials

Several of the Cores in the Biomedical Research Core Facilities offers products for sale to help you with your research projects. From enzyme kits and reagents to mouse models and gene panels.

Learn More About Essential Research Materials
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Expert Scientific Guidance

The BRCF can help you discover technology, find experts, and advance your research every step of the way. Consult with the Cores or attend a training event to collaborate with top experts and take advantage of the latest technology in research.

Learn More About Expert Scientific Guidance
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Specialized Research Services

Whether you need to drop off a sample of DNA or cells for imaging, obtain expert analysis, or store your samples, the BRCF are here to assist you.

Learn More About Specialized Research Services
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Access to Tools & Technologies

Cutting-edge technology and dozens of instruments in the fields of Flow Cytometry, and Microscopy Image & Analysis are available through the BRCF, and self-service and technician-operated options are available.

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Research Materials

Several Cores in the Biomedical Research Core Facilities offer products for sale to help you with your research projects. From enzyme kits and reagents to mouse models and gene panels. For more information, please visit:

Consultation & Training

The Biomedical Research Core Facilities (BRCF) can help you discover technology, find experts, and advance your research every step of the way. Consult with any of our Cores to collaborate with top experts and take advantage of the latest technology in research. We help establish the scope and budget of your project, coordinate applications for funding, offer comprehensive training for investigators, and more.

Many of our Cores offer their services to other academic and non-academic research institutions. Visit each Core’s specific website to learn more.

Specialized Services

Whether you need to drop off a sample of DNA or cells for imaging, the Biomedical Research Core Facilities are available to assist with your samples and data. Visit a specific core facility for more information.

Careers at the Cores

Smiling staff members

Current Open Positions

Biomedical Research Core Facilities (BRCF), part of the University of Michigan Medical School Office of Research, are campus-wide laboratories that develop and provide state-of-the-art scientific resources to enable biomedical research. Our mission is that we believe in serving you, advancing health, and paving the way for great discoveries in biomedical research at the University of Michigan and beyond.

View Our Current Opening Positions

Grant Resources

Supporting Effort for BRCF Staff on Your Grant

BRCF Core Directors & Leadership are open to discussing and considering BRCF staff providing intellectual or sample preparation support as percent effort on grants.

Please reach out to the specific Core Director for more information.

Naming Staff in your Grant

BRCF staff can be named as CO-I, Senior or Key Personnel, or Other Staff Scientist in your grant. Please reach out to the specific Core Director of the staff member you wish to include.

Facilities & Resources Template Language for Grant Applications

Biomedical Research Core Facilities (BRCF), a unit of the University of Michigan Medical School Office of Research, are campus-wide laboratories that provide state-of-the-art scientific resources to facilitate biomedical research. Formed in 1986, the BRCF offers centralized access to research services, shared equipment, and technical expertise. Our mission is to foster an environment of innovation and efficiency that serves our research community and supports biomedical science from insight to impact.

Core Facilities aim to ensure centralized access to the latest instrumentation and services for investigators, avoiding the duplication of institutional expenses and efforts. Core instrumentation is regularly upgraded to keep pace with the rapid advances in biomedical research. Cores have highly trained staff to carry out investigator projects, and provide workshops and training opportunities to researchers, enhancing efficiency, rigor, and reproducibility for multiple users.

The BRCF is a fee-for-service provider, offering these services at a reasonable cost. We use MiCores as a single portal for investigators to request services from our facilities. MiCores is a scheduling, billing, and reporting system that is fully integrated into the University of Michigan financial system.

Letters of Support

Each individual Core Director or the BRCF Director can provide a letter of support for your grant applications. Please provide us:

  • Title of the Grant
  • Type of Grant
  • What date you need the letter
  • Who you would like the letter from

Send requests to [email protected].

Questions on BRCF Grant Support, Pre, Post, Percent Efforts?

Contact [email protected].

External Customer Information

What is MiCores?

MiCores (iLabs) is an operational software platform powered by Agilent Technologies and used by the BRCF to perform ordering, billing, and scheduling of scientific products and services. For more information about MiCores and how to register, visit the MiCores website.

What if I Don't Know Which Core I Need?

Fill out our contact form and submit your question using “I have a project that may involve multiple cores.”

Requesting Services

The BRCF Cores use the MiCores (iLab software) platform to request services. Please complete the following steps to register in iLab and request services if you are not already set up:  

Register for an account

Once an email is received stating you have access to iLab, return to the URL and log in: 

  • Request access to the desired Core
  • After you receive access to the Core:
    • Complete all contact information
      • For the lab/company requesting the service
      • Institution/Company’s Accounts Payable address to receive/pay invoices
    • Enter your payment information in the ‘Purchase Order’ (PO) field.
      • If using a purchase order, enter your PO# and attach the PO document. If you do not yet have a PO#, simply type ‘purchase order’ and update with the PO# when available in order for work to begin
      • If using a credit card, simply type ‘credit card’; a fee of approximately 3.6% will be added to credit card invoices per University policy
      • PLEASE DO NOT ENTER YOUR CREDIT CARD INFORMATION AT THIS TIME
      • Orders will be billed once the work is completed; an invoice will be sent from UM Accounts Receivable with payment instructions.
Fee-for-Service with Customers External to the University of Michigan

Fee-for-Service work requires a signed services agreement and a purchase order before the work can begin. Consult with the core you wish to work with for estimates and project design.

  • Standard Services Agreement Template
  • Purchase Order Preparation
Setting up the University of Michigan as Your Vendor

Need to set us up as a supplier in your system? We can provide you with documents such as W-9, Federal and State Sales Tax Exemptions, Certificates of Insurance, and any other information you may need. Please reach out to [email protected].

Making Payments

The University of Michigan will send your institution an invoice once the work is completed. Please do not send payment until you have received an invoice.

Online Credit Card Payment Portal

Wire Transfers for International Payments

EFT/ACH Payments can be made directly to the university. Refer to the bottom of your invoice for U-M bank account details, or contact us for further payment instructions at [email protected].

Paying by check: Reference your invoice number and/or customer number on your check payable to “The Regents of the University of Michigan” and mail to the following secure address:

The Regents of the University of Michigan
Box 223131
Pittsburgh, PA 15251-2131

MiCores and M-Pathways Billing Guide

System Overview
  • Platform Identity: iLabs (branded as MiCores at the University of Michigan) is the primary operational software used across the Biomedical Research Core Facilities (BRCF) for service requests and billing.
  • Real-Time Integration: An API connects MiCores directly to the university’s M-Pathways financial system.
  • Instant Verification: This integration provides investigators and laboratory staff real-time access to valid shortcodes for seamless service tracking and ordering.
Monthly Billing Workflow
  • Service Completion: Once core services are rendered, BRCF Core Directors or their staff log them as complete within the system.
  • Monthly Transfers: At least once per month, core personnel initiate a formal billing event to transfer these charges from MiCores to M-Pathways.
  • Shortcode Funding: Transactions are uploaded via a Service Unit Billing (SUB) file, which automatically applies the designated charges directly to the shortcodes previously selected by the lab.
Post-Billing Shortcode Corrections
  • Required Action: If a shortcode needs to be changed after a service has already been billed, customers must contact the respective Core Director directly to request the modification.
  • Necessary Details: To process the change, you must provide the Core Director with:
    • The unique Service ID number
    • The original shortcode used
    • The new shortcode to be applied
  • Resolution Process: The Core Director will update the shortcode within MiCores and resubmit a corrected SUB file.
  • Final Correction: Once the updated SUB file is uploaded into M-Pathways, the shortcode change will be completed.
  • Audit Compliance: This structured process keeps MiCores and M-Pathways data perfectly synchronized while maintaining a transparent audit trail explaining why the modification was required.

Frequently Asked Questions

Due to the diversity of our work, many of our cores have developed their own frequently asked questions (FAQs). Please visit each of our core websites to learn more about services and troubleshooting.

How do I get started with the BRCF?

Because each core offers a variety of services, they all have slightly different processes for beginning work with them; however, most project requests begin with a consultation. Check out the page of your core of interest to find out more, or view their “Contact Us” information to find out who to get in touch with.

What if I don't know which core I need?

Fill out our contact form and submit your question using “I have a project that may involve multiple cores.”

How many cores are there within the BRCF?

There are currently 11 cores under the BRCF umbrella; however, many cores exist at the University of Michigan. To learn more about all of the cores located at U-M, please visit the Michigan Research Cores website.

What is MiCores?

MiCores is an operational software platform powered by Agilent Technologies and used by the BRCF to perform ordering, billing, and scheduling of scientific products and services. For more information about MiCores and how to register, visit the MiCores website.

Are there any funding resources available?

There are many funding opportunities across the university and beyond. Highlighted below are some that are most applicable to the Biomedical Research Core Facilities. Please visit the UMMS Office of Research Funding & Proposal Development page for information about internal funding, external funding opportunities, bridging support, and more.

Does the BRCF have any authorship and acknowledgement policies?

The Association of Biomolecular Resource Facilities (ABRF) has established recommended authorship guidelines that the Biomedical Research Core Facilities follow. Please see below for their recommended guidelines as implemented by the BRCF:

Why cite the contributions of a core?

It is important to document the use of each Biomedical Research Core Facility by investigators in publications. Doing so facilitates efforts to obtain funding for our cores. Core facility personnel are valued scientists; when they make a substantial contribution to a publication, they deserve to be acknowledged like any other co-author. 

The existence of the BRCF relies on proper acknowledgment in publications and awards. Proper acknowledgment of the BRCF helps us to obtain support so that we may continue to provide services to the best of our abilities.

Please include the following information in the acknowledgments section of any publication resulting from services provided by or facilities used by any of the BRCF Cores:

  1. The name of the specific Biomedical Research Core Facility(ies) used in the scope of your research or project.
  2. Clearly state how the author and core contributed to your research.
  3. If a center, department, grant, or institution supported access to resources through funding or other means, please include that.

Statement Example

“In collaboration with this research, we acknowledge support from the University of Michigan Biomedical Research Core Facilities (Insert BRCF Core Name Here).”

If you have any questions about correctly attributing the cores in a publication or award, please contact us.

For more information, please see the Authorship Guidelines established by the ABRF.

Where are the cores located?

The BRCF administration office is located on the C-floor (C570) of Medical Science Research Building II (MSRB II). Each of our cores is spread out across campus, including MSRB II, Biomedical Research Science Building (BSRB), Life Sciences Institute (LSI), Brehm, and North Campus Research Complex (NCRC).

How do I get to the MSRB II C-Floor?

The C-Floor can only be accessed by using the elevators in Medical Science Research Building II. Use the directions or map below to navigate to MSRB II.

Entering from 1150 W. Medical Center Dr. (MSRB II)

If you come through the main entrance at the circle drive, take the door to your left that reads “MSRB II” and use those elevators to arrive at the C-Floor. You can also take the open staircase to the left of the entrance. View the directions to MSRB II on a map.

Entering from 1137 Catherine St. (Med Sci II)

If entering through the 4th floor of Medical Science Building II (Med Sci II), head left from the entrance and follow the hallway straight down until it dead-ends at a stairwell. Once through that doorway, take the small flight of stairs to your left onto the 4th floor of MSRB I. From there, follow the hallway to the right until you reach the MSRB II elevators. View the directions to Med Sci II on a map. 

Similarly, from the main entrance to the 3rd floor of Medical Science Building II (Med Sci II), head right down the long hallway until it dead-ends at a stairwell. Once through that doorway, take the small flight of stairs to your left onto the 3rd-floor MSRB I. From there, follow the hallway to the right until you reach the MSRB II elevators. View the directions from the main entrance to Med Sci II on a map.

Entering from the Cancer Center of University Hospital

If entering from the Rogel Cancer Center parking structure, take the elevators to the 7th-floor skywalk and take a right at the first set of doors (this is the 3rd floor of Med Sci I). This will take you down a long hallway that opens up into Med Sci II. Take a right at the vending machines until you reach the stairwell. Once through that doorway, take the small flight of stairs to your left onto the 3rd floor of MSRB I. From there, follow the hallway to the right until you reach the MSRB II elevators. Follow these same directions if coming directly from the Cancer Center or UH. You must be on the 2nd floor of either building to connect to the 3rd floor of Med Sci I and II. View a more detailed map indicating directions from multiple sites at Michigan Medicine (note: this is a large file).

Blueprint map showing directions to BRCF through University Hospital

Contact Us

Biomedical Research Core Facilities
Office of Research, University of Michigan Medical School
C560 MSRB II
1150 W. Medical Center Dr.
Ann Arbor, MI 48109-0674
Phone: 734-936-2638

About Us

The Biomedical Research Core Facilities (BRCF) are part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact.
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Upcoming Research Events

All Office of Research Events
8 20 2026 2:00 pm 8 20 2026 - 3:00 pm

The Funding Forum

Join the Grant Services and Analysis Research Development (RD) team on Zoom every third Thursday at 2:00 pm for the Funding Forum – a 60-minute session designed to help UMMS faculty gain an advantage in grant seeking and proposal development.
Event runs May 21, 2026 - December 17, 2026
A person sits at a laptop at BSRB.
9 3 2026 1:00 pm 9 3 2026 - 2:00 pm

From Discovery to Development: Reducing Risk After Identifying a Lead Compound Webinar (Part of the Rogel Cancer Center Innovation Program)

Learn more from this webinar series featuring case study lectures from experts in the field.
FFMI Mukesh Nyati lab
9 8 2026 1:00 pm 9 8 2026 - 2:00 pm

U-M Resources for Therapeutic Innovations Webinar (Part of the Rogel Cancer Center Innovation Program)

Learn more from this webinar series featuring case study lectures from experts in the field.
FFMI Mukesh Nyati lab
9 15 2026 11:00 am 9 15 2026 - 2:00 pm

Researchpalooza

Join exhibitors from labs and offices of the Medical School and across campus for this annual event showcasing the services provided to research faculty, staff, and students.
people at Researchpalooza event outdoors
9 17 2026 2:00 pm 9 17 2026 - 3:00 pm

The Funding Forum

Join the Grant Services and Analysis Research Development (RD) team on Zoom every third Thursday at 2:00 pm for the Funding Forum – a 60-minute session designed to help UMMS faculty gain an advantage in grant seeking and proposal development.
Event runs May 21, 2026 - December 17, 2026
A person sits at a laptop at BSRB.
9 22 2026 10:00 am 9 22 2026 - 11:00 am

Best Practices for Preparing Large Team Grant Proposals

The Large Team Grant Core hosts a virtual seminar addressing best practices for submitting complex, interdisciplinary grant proposals.
group in a meeting at a table seen from above
10 12 2026 8:00 am 10 12 2026 - 6:00 pm

Dean's Lecture Symposium

The Dean's Lecture Symposium will offer a day of panel sessions, a poster session, and keynote speaker Sean Morrison from UT-Southwestern.
stem cells
10 15 2026 2:00 pm 10 15 2026 - 3:00 pm

The Funding Forum

Join the Grant Services and Analysis Research Development (RD) team on Zoom every third Thursday at 2:00 pm for the Funding Forum – a 60-minute session designed to help UMMS faculty gain an advantage in grant seeking and proposal development.
Event runs May 21, 2026 - December 17, 2026
A person sits at a laptop at BSRB.
10 22 2026 8:00 am 10 22 2026 - 5:00 pm

Write Winning NIH R01 Grant Proposals

This full-day workshop is an annual event for R01 Boot Camp participants, and will be open again this year to U-M faculty members, postdoctoral researchers and administrative staff interested in gaining a competitive edge in grantsmanship.
Faculty and Dr. Robertson in the auditorium at Palmer Commons

Featured Research News

All Office of Research News
Image of an investigator at a meeting with two other people. Investigator is on their computer as the other two people are looking at documents. It only shows individuals from the neck down.
Office of Research

Upcoming Changes to Clinical Research Billing Coverage Analysis Process

To align Michigan Medicine with current best practices, a new process will be implemented to support robust clinical research billing coverage analysis. Starting this September, coverage analysis will be created centrally for all new clinical trials with billable items and services and will include citations of national and local care determinations.
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Office of Research

New Research Team Collaboration Agreement Template

The Office of Regulatory Affairs has developed a Research Team Collaboration Agreement, a template to help teams establish and maintain clear communication through the project lifecycle.
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Office of Research

New Requirement for Dual Appointment VA Faculty Serving as PIs on U-M Sponsored Projects

Veterans Administration (VA) and University of Michigan dual-appointed faculty proposing research through U-M often plan to use resources (space, staff, subject pools, equipment, etc) at the VA. In these circumstances, the national VA requires that a Federal Conflict of Interest (FCOI) waiver be received BEFORE the application is submitted (18 U.S.C. §208). To support the VA in achieving compliance, Michigan Medicine is implementing a review of disclosure prior to U-M submission. Beginning July 1, 2026, all VA–U-M dual-appointed faculty serving as a PI and using resources that require VA regulatory approval must obtain an FCOI waiver through the VA before submitting the grant through U-M.
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Many Voices, Our Michigan

At Michigan Medicine, we unequivocally recognize racism as a public health issue and we stand together against bias and inequality.

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