Neuroscience
Advancing Neuroscience Research at Michigan Medicine
Unlocking the complexities of the brain and reducing the impact of brain-related illnesses.
The brain regulates the body’s organ systems and helps us interact with the world. Understanding how the brain coordinates signals from inside and outside of the body and drives our health and behavior is the focus of Michigan Medicine’s world-renowned neuroscientists.
Our researchers are quickly advancing knowledge within the field, from understanding diseases of the brain, such as cancer, epilepsy and depression arise to unraveling the brain’s immense complexity.
The Fundamentals
Today on The Fundamentals is Dr. Maria Castro, the R.C. Schneider collegiate professor of neurosurgery, and a professor of cell and developmental biology at the University of Michigan Medical School. Her research program aims to develop immunotherapies for primary and metastatic brain cancer, studying basic immune biology mechanisms leading to clinical implementation. She has been inducted into the American Association for the Advancement of Sciences, the Latin American Academy of Sciences, and the American Institute for Medical and Biological Engineering College of Fellows. She has won numerous awards for her contributions to basic science and cancer research and is a diversity ambassador for the Cancer Biology Graduate Training Program.
You can learn more about Dr. Castro here, and you can follow her @castro2355_mg, the Rogel Cancer Center @UMRogelCancer, the department of neurosurgery @umichneuro, Michigan Neurscience Institute @UM_MNI and the department of cell and developmental biology @UMCDB on X
Health Lab Podcast
A study finds intriguing brain wave patterns in comatose patients who died following cardiac arrest.
Health Lab Podcast
Study suggests that the overexpression of cochlear neurotrophin-3 can help prevent the loss of hearing.
Health Lab
In a recent study, using network neuroscience, investigators found a way to objectively determine the balance of integration and segregation in fMRI-measured brain signals during wakefulness as well as during sleep and anesthesia.
Health Lab
Dementia doesn’t just erode memory – it also changes behavior and mental health. A new study shows the brain’s salience network and tau protein may be involved.
Health Lab
Dementia risks vary by person and by population. But a new study shows diagnosis of the disease varies by region even after those differences are taken into account.
Meet the Experts
Michigan Medicine neuroscience researchers are at the forefront of groundbreaking discoveries that shape the understanding of the brain and nervous system.
Applications of oxetanes in drug discovery and medicinal chemistry
Huang, G,
Hucek, D,
Cierpicki, T,
Grembecka, J,
Eur J Med Chem, 2023 Dec; DOI:10.1016/j.ejmech.2023.115802 Refractory generalized myasthenia gravis with myasthenic incomplete ophthalmoplegia successfully treated with eculizumab
Weidmayer, SL,
Gallagher, G,
Am J Ophthalmol Case Rep, 2023 Dec; DOI:10.1016/j.ajoc.2023.101925 Optoα1AR activation in astrocytes modulates basal hippocampal synaptic excitation and inhibition in a stimulation-specific manner
Courtney, CD,
Sobieski, C,
Ramakrishnan, C,
Ingram, RJ,
Wojnowski, NM,
DeFazio, RA,
Deisseroth, K,
Christian-Hinman, CA,
Hippocampus, 2023 Dec; DOI:10.1002/hipo.23580 Predicting Neurologically Intact Survival for Advanced Age Adults After Successful Resuscitation of Out-of-Hospital Cardiac Arrest
Adams, D,
Nathanson, BH,
White, CN,
Jackson, EA,
Mader, TJ,
Coute, RA,
CARES Surveillance Group, Array,
Am J Cardiol, 2023 Nov; DOI:10.1016/j.amjcard.2023.08.108 Neuropeptide Y signaling regulates recurrent excitation in the auditory midbrain
Silveira, MA,
Drotos, AC,
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J Neurosci, 2023 Nov; DOI:10.1523/JNEUROSCI.0900-23.2023 Magnetic resonance fingerprinting in multiple sclerosis
Ontaneda, D,
Gulani, V,
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Shah, A,
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Ma, D,
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Cohen, JA,
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Mult Scler Relat Disord, 2023 Nov; DOI:10.1016/j.msard.2023.105024 Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping
Iglesias, AG,
Chiu, AS,
Wong, J,
Campus, P,
Li, F,
Liu, ZN,
Bhatti, JK,
Patel, SA,
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Burgess, CR,
Flagel, SB,
J Neurosci, 2023 Nov; DOI:10.1523/JNEUROSCI.0848-23.2023 Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme
Dulchavsky, M,
Mitra, R,
Wu, K,
Li, J,
Boer, K,
Liu, X,
Zhang, Z,
Vasquez, C,
Clark, CT,
Funckes, K,
Shankar, K,
Bonnet-Zahedi, S,
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Calabrese, AN,
George, O,
Stull, F,
Bardwell, JCA,
Nat Chem Biol, 2023 Nov; DOI:10.1038/s41589-023-01426-y Department of Biological Chemistry
Department of Biomedical Engineering
Department of Computational Medicine and Bioinformatics
Department of Learning Health Sciences
Department of Microbiology and Immunology
Department of Emergency Medicine
Department of Internal Medicine
Department of Obstetrics and Gynecology
Department of Orthopaedic Surgery
Department of Otolaryngology-Head and Neck Surgery
