ALS Center of Excellence
Leading the fight against ALS.


Learn about the ALS Center of Excellence.

Pranger ALS Clinic

See where our clinical research and care take place.


Learn about our groundbreaking ALS research.


Support ALS research and clinical care.


Get to know the people behind the Center.


Learn about the hub of our basic science research.

Making ALS a Preventable Disease

A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.  

We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease. 

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what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death. 

Scott Matzka dropping the puck at the IceALS game Impact
ALS incidence is predicted to rise globally by 2040.
Veterans are more likely to have ALS than others.
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
Clinical Trials & Observational Studies

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Groundbreaking Basic Science Research

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ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

See All Screenshot from NASEM Living with ALS infographic
Research News
NASEM Report Released: Living with ALS
Eva Feldman, M.D., Ph.D., was part of a committee put together by the National Academies of Sciences, Engineering and Medicine (NASEM) to identify and recommend key actions for the public, private, and nonprofit sectors to undertake to make ALS a livable disease within a decade.
photo of Arthur Lupia and Stacey Jacoby
Research News
NeuroNetwork Managing Director Wins Office of Research Award
Stacey Jacoby, Ph.D., received the Research Study Coordinator/Manager Recognition Award.
a pile of different types of plastic garbage
Research News
Nanoplastics and ALS
A new study examines how tiny plastic particles can harm the body and their possible link to ALS.
photo of a production worker that is AI generated
Research News
First-of-its-Kind ALS Study Funded by CDC
Funded by the CDC, the Michigan Brain, Health and Environment Study is the first-of-its-kind ALS study led by Drs. Eva Feldman and Stephen Goutman.
an AI generated image of neutrofils and nerves
Research News
ALS Immune Findings Yield Important Results
A new study by Dr. Benjamin Murdock uncovers important information that will shape therapeutic strategy, diagnosis, and prognosis in ALS.
a photo of a dancer
Research News
Women Defining Themselves: A Benefit Concert for the ALS Center of Excellence
Watch Women Defining Themselves: A Benefit Concert for the ALS Center of Excellence.