ALS Center of Excellence
Leading the world in the fight against ALS


Learn about the ALS Center of Excellence

Pranger ALS Clinic

Visit the site for our clinical research


Learn about our groundbreaking ALS Research


Support ALS research and clinical care


Get to know the people behind the Center


Learn about the base of our ALS lab research

Working toward making ALS a Preventable Disease

A world leader in the fight against ALS, our ALS Center of Excellence features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team. 

We are collaborating with research leaders across the globe on a multi-faceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease.

newsletter signup

Subscribe to our mailing list for updates regarding our clinic and research

what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death.

als Impact
ALS incidence is predicted to rise by 2040.
Veterans are more likely to have ALS than others.
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
Clinical & Observational Studies

Learn More
Groundbreaking Basic Science Research

Learn More

ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

See All
Research News
Dr. Feldman at Distinguished Professor Lecture Series
Last year, Dr. Eva Feldman was named the James W. Albers Distinguished University Professor, the University of Michigan’s highest faculty honor. Dr. Feldman chose to name hers after her longtime friend and mentor, Dr. James Albers, U-M Professor Emeritus of Neurology, Psychiatry, and Physical Medicine and Rehabilitation.
Research News
Mini Symposium Series: Environment, Health & Policy
In our latest installment, U.S. Rep. Debbie Dingell sat down to talk to Dr. Eva Feldman about the environment, health, and public policy. Afterward, Dr. Feldman was joined by two esteemed panelists, Drs. Bhramar Mukherjee and Barry Rabe for a live Q&A.
Research News
Drawing a tube of blood could assess ALS risk from environmental toxin exposure
Over the last decade, research at Michigan Medicine has shown how exposure to toxins in the environment, such as pesticides and carcinogenic PCBs, affect the risk of developing and dying from amyotrophic lateral sclerosis.
Research News
Gut Microbiome Provides New Therapeutic Target for ALS
Brain, one of the top academic journals, published groundbreaking new research by Dr. Feldman et al. that looked at the connection between the microbiome, fatty acids in the blood, and ALS.
Research News
The ALS Exposome in Nature Reviews Neurology
Just what is the exposome? Eva Feldman, M.D., Ph.D., James W. Albers Distinguished University Professor, and Russel N. DeJong Professor of Neurology, explains that it is the amalgamation of what comes into our body from the outside.
Department News
Clinic Q&A: Nurse & Nerve Center Sandy Lemkin
The theme for Nurses Week this year is “You Make a Difference.” In our own Pranger ALS Clinic is a perfect example of someone who not only makes an incredible difference in the lives of so many ALS patients and their families but also impacts her coworkers and how effectively are clinic operates.