ALS Center of Excellence
Leading the fight against ALS.
als

About

Learn about the ALS Center of Excellence.

Pranger ALS Clinic

See where our clinical research and care take place.

Research

Learn about our groundbreaking ALS research.

GIVING

Support ALS research and clinical care.

People

Get to know the people behind the Center.

NEURONETWORK

Learn about the hub of our basic science research.

Making ALS a Preventable Disease

A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.  

We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease. 

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what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death. 

Scott Matzka dropping the puck at the IceALS game Impact
70%
ALS incidence is predicted to rise globally by 2040.
2X
Veterans are more likely to have ALS than others.
90%
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
clinical_studies
Clinical Trials & Observational Studies

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als
Groundbreaking Basic Science Research

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ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

NEWS & EVENTS
See All graphic for ALS Awareness Month
Research News
The Impact of ALS
In honor of ALS Awareness Month, the team and supporters of the ALS Center of Excellence shared their takes on the impact of amyotrophic lateral sclerosis (ALS).
crop of Go On, Be Brave flier
Research News
Dr. Feldman to speak at ALS documentary screening
Dr. Eva Feldman will speak before a documentary about a woman with ALS who is racing against time to complete a marathon in each of the 50 states.
a photo of Dr. Eva Feldman receiving the Sheila Essey Award with James Essey
Research News
Dr. Eva Feldman Wins Prestigious ALS Award
The ALS Association, American Academy of Neurology (AAN), and American Brain Foundation awarded the 2024 Sheila Essey Award to Eva Feldman, M.D., Ph.D., at the AAN's annual meeting in April.
Xray of a stem cell in a mouse brain.
Health Lab
Stem cells improve memory, reduce inflammation in Alzheimer’s mouse brains
Researchers improved memory and reduced neuroinflammation in a mouse model of Alzheimer’s Disease, suggesting another avenue for potential treatment.
Cover of Neurology Today April 4, 2024 issue with Eva Feldman
Research News
Neurology Today Features Dr. Feldman on Cover
Featured on the cover and in a subsequent story of the American Academy of Neurology's Neurology Today, Dr. Eva Feldman explored the environmental triggers of neurodegenerative disease.
Photo of a cluttered, messy garage
Health Lab
Chemicals stored in home garages linked to ALS risk
A Michigan Medicine study finds that storing chemicals in a garage at home may associate with an increased risk of ALS.
Women Defining Themselves
The University of Michigan School of Dance is producing a special evening of dance, music, and song to raise awareness for ALS. The performances on May 11 are inspired by a dance you contracted ALS at a young age.
A photo of a female danger