J. Michelle Kahlenberg Lab

Our research focuses on uncovering the mechanisms that drive lupus, lupus flares and the development of subsequent complications.

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J. Michelle Kahlenberg, MD, PhD
Principal Investigator

Giles G Bole MD and Dorothy Mulkey MD Research Professor of Rheumatology
Department of Internal Medicine Vice Chair for Basic & Translational Research
Professor of Internal Medicine and Dermatology

Email: [email protected] | X: @Kahlenberglab

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Tammi Reed
Michigan Medicine
1150 W. Medical Center Drive
5568 MSRB 2
Ann Arbor, MI 48109
Phone: 734-764-2535

Dr. Michelle Kahlenberg presents "Investigating the Causes of Flares in Autoimmune Disease", followed by Dr. Joseph McCune who discusses the mission and goals of the Lupus Program.

Current Research
in the Kahlenberg Lab

Lupus, a systemic autoimmune disease, causes widespread inflammation and tissue damage, challenging the body in myriad ways. This devastating, unpredictable condition can affect anyone. As many as 1 million Americans have lupus, with that number reaching 5 million worldwide, according to the Lupus Foundation of America.

Because it is chronic, patients suffer through remissions and flare-ups for years. Complications such as accelerated heart disease and kidney damage increase mortality for lupus patients. Lupus can impact any part of the body, which means we engage physicians and scientists across our health system.

Collaboratively, we are invested in learning more about what causes lupus, how flare-ups can be prevented, how to predict disease progression, and how to prevent permanent organ damage. Our lab is especially interested in understanding how triggers like skin bacteria or ultraviolet light can stimulate the immune system to go into over-drive and cause damage.

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doctor with patient white and black patient ignored
Health Lab
Fixing racial inequities in lupus care
When it comes to lupus care, Black adults are normally left behind despite being one of the highest lupus populations.
friends hugging purple butterflies
Health Lab
Lupus: A frustrating diagnosis journey you don’t need to embark alone
Nicknamed the “invisible disease”, the autoimmune disorder comes with lifestyle changes that can be a challenging adjustment.
Research News
Vice Chair for Basic and Translational Research - Dr. Michelle Kahlenberg
The Department of Internal Medicine is excited to share that J. Michelle Kahlenberg, MD, PhD has accepted the position of Vice Chair for Basic and Translational Research within the department, effective June 1, 2023.