Keith Andrew Casper, MD
Clinical Associate Professor of Otolaryngology-Head and Neck Surgery
Head and Neck Surgical Oncology & Microvascular Reconstruction Division Chief
Otolaryngology-Head and Neck Surgery Medical Director of Clinical Growth
Medical School
Available to mentor
Keith Andrew Casper, MD
Clinical Associate Professor
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Research Overview
My research interests relate to outcomes and quality improvement in head and neck cancer. I spent an additional year of training after residency specializing in head and neck oncology and microvascular reconstruction. The University of Michigan has a cohesive, collaborative group of surgeons, radiation oncologists, medical oncologists, and basic science researchers interested in advancing the field of head and neck cancer.
Recent Publications
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Mierzwa M, Rosen B, Suresh K, Dinesh A, Regan S, Brummel C, Wong K, Casper K, Prince M, Malloy K, Shuman A, Chinn S, Cao Y, Aryal M, Heft-Neal M, Stucken C, Buchakjian M, Forner D, Yalamanchi P, Swiecicki P, Lawrence TS, Akhdar R, Tewari M, Bhambhani C, Walline H, Brenner JC, Shah J, Worden F. Clinical Cancer Research an Official Journal of the American Association for Cancer Research, 2026 Feb 17; 32 (4): 684 - 693.Journal ArticleFDG-PET-Based Selective Deescalation of Chemoradiation in Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma: A Multicenter Phase II Trial
DOI:10.1158/1078-0432.CCR-25-2820 PMID: 41385605 -
Regan SN, Shah J, Suresh K, Morales KA, Cao Y, Aryal M, Rosen BS, Walline H, Lee C, Aldous J, Swiecicki PL, Casper KA, Chinn SB, Malloy KM, Prince MEP, Stucken CL, Shuman AG, Heft-Neal M, Lyden TH, Blakely A, Ambrose M, Chad Brenner J, Worden FP, Mierzwa ML. Advances in Radiation Oncology, 2025 Oct 1; 10 (10):Journal ArticleProspective Phase II Trial of Definitive Chemoradiation and Concurrent Nivolumab in Locally Advanced p16+ Oropharynx Cancer
DOI:10.1016/j.adro.2025.101832 -
Smith JD, Gensterblum-Miller E, Forner DWA, Yalamanchi P, Buchakjian MR, Chinn SB, Shuman AG, Casper KA, Malloy KM, Stucken CL, Mclean SA, Mierzwa ML, Shah J, Swiecicki PL, Worden FP, Prince MEP, Spector ME, Brenner JC, Heft Neal ME. Otolaryngology Head and Neck Surgery United States, 2025 Sep 1; 173 (3): 645 - 650.Journal ArticleTumor Hypoxia and CD8+ T-Cell Infiltration in Patients With Advanced Laryngeal Cancer
DOI:10.1002/ohn.1291 PMID: 40323140 -
Regan SN, Shah J, Suresh K, Morales KA, Cao Y, Aryal M, Rosen BS, Walline H, Lee C, Aldous J, Swiecicki PL, Casper KA, Chinn SB, Malloy KM, Prince MEP, Stucken CL, Shuman AG, Heft-Neal M, Lyden TH, Blakely A, Ambrose M, Brenner JC, Worden FP, Mierzwa M. Advances in Radiation Oncology, 2025 Aug 15; 101832 - 101832.Journal ArticleProspective Phase II Trial of Definitive Chemoradiation and Concurrent Nivolumab in Locally Advanced p16+ Oropharynx Cancer
DOI:10.1016/j.adro.2025.101832 -
Bughrara MS, Worden FP, Buxo Z, Hochfelder C, Chinn SB, Mierzwa ML, Shah JL, Casper K. Journal of Clinical Oncology, 2025 May 30; 43 (16_suppl): e18107 - e18107.Journal ArticleResponse adapted oncologic surgery following neoadjuvant immunotherapy and chemotherapy for resectable locally advanced oral cavity and oropharyngeal squamous cell carcinoma.
DOI:10.1200/jco.2025.43.16_suppl.e18107 -
Edwards DM, Gharzai LA, Wang W, Mayo C, Suresh K, Schipper M, Evans JR, Malloy K, Chinn SB, Prince M, Spector M, Shuman A, Stucken C, Swiecicki PL, Worden F, Jarema J, Henderson C, Kovach A, Brenner C, Shah JL, Mierzwa ML, Casper K. Head and Neck, 2024 Nov 1; 46 (11): 2687 - 2698.Journal ArticleFollow-up for human papillomavirus-related oropharynx cancer concentrated on unequal symptom change (FOCUS): Prospective patient-reported outcome collection
DOI:10.1002/hed.27778 PMID: 38680087 -
Regan SN, Aryal MP, Suresh K, Rosen BS, Walline H, Prince ME, Malloy K, Casper K, Shuman A, Chinn SB, Heft-Neal ME, Swiecicki PL, Worden F, Shah JL, Cao Y, Brenner C, Mierzwa ML. International Journal of Radiation Oncology • Biology • Physics, 2024 Oct 1; 120 (2): s131 - s131.Proceeding / Abstract / PosterImaging Metrics and HPV ctDNA Kinetics in a Phase II Immuno-Chemoradiation Trial for Locoregionally Advanced p16+ Oropharynx Cancer
DOI:10.1016/j.ijrobp.2024.07.238 -
Kazemi RJ, Prince ADP, Casper KA, Spector ME, Smith JD, Prince MEP. Oto Open, 2024 Oct 1; 8 (4):Journal ArticleRetrospective Exploration of Botulinum Toxin Injection for Pharyngoesophageal Segment Dysfunction Post-laryngectomy
DOI:10.1002/oto2.181
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