Di Chen, PhD

 headshot of Di Chen
Assistant Research Scientist
Microbiology and Immunology
Medical School
University of Michigan Medical School
Department of Microbiology and Immunology
1150 West Medical Center Drive
Ann Arbor, Michigan 48109
[email protected]
Available to mentor
Di Chen, PhD
headshot of Di Chen
Assistant Research Scientist
  • Qualifications
  • Recent Publications

  • Manage Your Profile

    • Qualifications
    • Postdoctoral Research Fellow
      University of Michigan Medical School, Department of Microbiology and Immunology, Ann Arbor, United States
      2016 - 2021
      Postdoctoral Research
    • Postdoctoral Research Fellow
      Shanghai Institute of Nutrition and Health, Shanghai, China
      2013 - 2015
      Postdoctoral Research
    • PhD
      Huazhong University of Science and Technology, Wuhan, China
      2007 - 2013
    • MS
      Hubei University, Wuhan, China
      2004 - 2007
    • BSc
      China Three Gorges University, Yichang, China
      2000 - 2004

    Recent Publications

     See All Publications
    • Journal Article
      Dental pulp lymphatic vessel dynamics during tooth development and pulp stimulation in rodents
      Tazawa K, Chen D, Fujimura A, King PD, Sasaki H. International Endodontic Journal, 2025 Aug 1; 58 (8): 1197 - 1210. DOI:10.1111/iej.14244
      PMID: 40277146
    • Journal Article
      The C2 domain augments Ras GTPase-activating protein catalytic activity
      Paul ME, Chen D, Vish KJ, Lartey NL, Hughes E, Freeman ZT, Saunders TL, Stiegler AL, King PD, Boggon TJ. Proceedings of the National Academy of Sciences of the United States of America, 2025 Feb 11; 122 (6): DOI:10.1073/pnas.2418433122
      PMID: 39899710
    • Journal Article
      A temporally-restricted pattern of endothelial cell collagen 4 alpha 1 expression during embryonic development determined with a novel knockin Col4a1-P2A-eGFP mouse line
      Lartey NL, van der Ent M, Alonzo R, Chen D, King PD. Genesis United States, 2024 Feb 1; 62 (1): DOI:10.1002/dvg.23539
      PMID: 37501352
    • Journal Article
      Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations
      Zhao S, Mekbib KY, van der Ent MA, Allington G, Prendergast A, Chau JE, Smith H, Shohfi J, Ocken J, Duran D, Furey CG, Hao LT, Duy PQ, Reeves BC, Zhang J, Nelson-Williams C, Chen D, Li B, Nottoli T, Bai S, Rolle M, Zeng X, Dong W, Fu PY, Wang YC, Mane S, Piwowarczyk P, Fehnel KP, See AP, Iskandar BJ, Aagaard-Kienitz B, Moyer QJ, Dennis E, Kiziltug E, Kundishora AJ, DeSpenza T, Greenberg ABW, Kidanemariam SM, Hale AT, Johnston JM, Jackson EM, Storm PB, Lang SS, Butler WE, Carter BS, Chapman P, Stapleton CJ, Patel AB, Rodesch G, Smajda S, Berenstein A, Barak T, Erson-Omay EZ, Zhao H, Moreno-De-Luca A, Proctor MR, Smith ER, Orbach DB, Alper SL, Nicoli S, Boggon TJ, Lifton RP, Gunel M, King PD, Jin SC, Kahle KT. Nature Communications, 2023 Dec 1; 14 (1): DOI:10.1038/s41467-023-43062-z
      PMID: 37978175
    • Journal Article
      Cutting Edge: Induced Loss of Rasgrp1 in Peripheral CD41 T Cells of Conditional Rasgrp1-Deficient Mice Reveals an Essential Role for Rasgrp1 in TCR/CD28-Induced Ras-MAPK Signaling
      Chang Y, Manivannan P, Doosti A, Lapinski PE, Chen D, Roose JP, King PD. Journal of Immunology, 2023 Sep 15; 211 (6): 917 - 922. DOI:10.4049/jimmunol.2300138
      PMID: 37566514
    • Journal Article
      EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans
      Chen D, Van der Ent MA, Lartey NL, King PD. Pharmaceuticals, 2023 Feb 1; 16 (2): DOI:10.3390/ph16020165
    • Proceeding / Abstract / Poster
      EPHB4 and RASA1 act together to restrict Ras-MAPK activation in endothelial cells necessary for normal blood vascular development
      Chen DI, Hughes E, Saunders T, Wu J, Hernandez Vasquez M, Makinen T, King P, Chen, PhD D. 2022 Oct 13;
    • Journal Article
      Angiogenesis depends upon EPHB4-mediated export of collagen IV from vascular endothelial cells
      Chen D, Hughes ED, Saunders TL, Wu J, Hernandez Vasquez MN, Makinen T, King PD. Jci Insight, 2022 Feb 22; 7 (4): DOI:10.1172/jci.insight.156928
      PMID: 35015735

    Featured News & Stories

         Bob Dickson, Teresa O'Meara, Mark Anderson, Siarhei Kharytonchyk, Di Chen
    Department News

    M&I is pleased to announce the promotion of 5 faculty members

    The Department of Microbiology and Immunology is pleased to announce the promotion of five faculty members.