Ananya Sen

University of Michigan researchers have shown that glucose levels sustain the increased STAT3 activation in colorectal cancer cells. Their findings suggest that targeting glucose metabolism could inhibit STAT3, leading to novel therapeutic strategies.

John Prensner, MD, PhD at University of Michigan Health C.S. Mott Children’s Hospital and research member at the Rogel Cancer Center is part of a research team called ILLUMINE which will receive a Cancer Grand Challenges award.

There has been little progress in understanding and treating liposarcoma due to its rarity and lack of research resources. In a new study, University of Michigan researchers have developed a novel mouse model that mirrors the disease in humans.

Josephine “JoJo” Wells, a spontaneous triplet, was diagnosed with rare hepatoblastoma at nine months old and treated with surgery and chemotherapy.

The Food and Drug Administration approved two drugs—daratumumab and linvoseltamab—for precursor conditions to multiple myeloma and relapsed multiple myeloma. Matthew Pianko answers questions about the current treatment options for multiple myeloma, the new FDA-approved drugs and what these treatments mean for patients.

University of Michigan researchers have found that a specific molecule called itaconate drives the development of ependymomas, a pediatric brain tumor. Their findings can help future drug development for children with this type of malignant brain tumor.

The University of Michigan has developed a machine learning model that’s discovered 17 environmental and social factors that can influence the risk of OHCA, including extreme temperatures, race, poverty and education levels.

The American Cancer Society reports that mortality rates have continued to decline since the 1990s. N. Lynn Henry, of Michigan Medicine, answers questions about how factors such as healthy lifestyle choices, early screening and clinical trials have improved cancer survival rates.

Karen Hollingsworth’s training as a nurse helped her identify the symptoms of a urinary tract infection and when it rapidly developed into septic shock.

Existing risk calculators for prostate cancer have less accurate estimates or predict risk through tests based on biopsy, which requires tissue samples and extra processing times. U-M researchers have developed a new model that can help doctors and patients understand their PSA results and what it means for patient life expectancy.

University of Michigan researchers uncover the role of occludin, a protein that regulates blood-brain and blood-retinal barriers, offering new insight into diabetic retinopathy.

Using a microfluidic device, researchers isolated glioblastoma biomarkers that can be used to predict patient responses to chemotherapy drugs.

University of Michigan researchers found a new protein target PP2A and developed a drug to treat non-small cell lung cancers that have KRAS mutations.

Michael Budd was diagnosed with Fuchs’ dystrophy and underwent surgery at Kellogg Eye Center, which fixed his vision issues.

Microbes create unique communities called microbiomes in the gut, oral cavity, skin and urogenital regions. Donnele Daley discusses common misconceptions about “healthy” microbes, the role of microbiomes in pancreatic cancer and future research directions.