Ananya Sen
Sen covers cancer clinical care and pediatric cancer research, ophthalmology, endocrinology, diabetes, emergency medicine, survival flight, and children's and women's health. Sen completed her Ph.D. in Microbiology from the University of Illinois Urbana-Champaign where she then worked as a science writer after graduation.
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7-year-old faces cancer treatment with ‘optimistic sassiness’
Emilia Pigeon was diagnosed with neuroblastoma, a type of cancer that starts in immature nerve cells. She was treated with chemotherapy and surgery and continues to do well.
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Dietary changes could provide a therapeutic avenue for brain cancer
A team of researchers from Michigan Medicine tracked how glucose is used in glioblastoma tumor cells. They showed that dietary interventions can slow brain cancer growth in mice.
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Brain neurons are responsible for day-to-day control of blood sugar
University of Michigan researchers have shown that a specific population of neurons in the hypothalamus help the brain maintain blood glucose levels under normal circumstances.
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FDA clears new DMG treatment: What it means for a deadly pediatric brain tumor
Diffuse midline gliomas are aggressive tumors that begin in the brain or spinal cord. It is universally fatal, and patients typically live for nine to 15 months after diagnosis. The FDA has approved ONC201 (dordaviprone) to treat recurrent H3K27M-mutant diffuse glioma. It's the first-ever FDA-approved treatment for this disease.
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New technology called PathoPlex maps the location of proteins inside cells
Abnormal changes in protein levels and patterns can result in diseases. Understanding protein organization can improve treatments and minimize disease symptoms. A team of researchers developed a new technology called pathology-oriented multiplexing, or PathoPlex, to map more than 140 different proteins across 40 tissue samples.
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Active surveillance helps men avoid unnecessary surgery for prostate cancer
About one in eight men in the United States are diagnosed with prostate cancer during their lifetime. However, each man’s risk can vary based on age, race, family history and lifestyle. Todd Morgan answers questions about the different stages of prostate cancer, when active surveillance is preferred and why surgical interventions can be harmful.
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Inactivation of key pathway boosts the body’s immune response against tumors
Immunotherapy uses the body’s immune system to recognize and destroy cancer cells. However, many patients are resistant to this therapy, which poses a challenge to their treatment. A study led by researchers from the University of Michigan showed that targeting CDK12/13 improves the effectiveness of cancer therapies.
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Amino acid glutamine is important for eye health
Photoreceptor death is the cause of vision loss in many retinal diseases, and there are no effective therapies that improve their survival. In a new paper, University of Michigan researchers studied the dependence of photoreceptors on glutamine.
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Protein targets can act as a switch for obesity and anorexia
In the U.S., dietary obesity has a prevalence of 40% and obesity increases the risk of other chronic diseases such as heart disease and diabetes. Even though anorexia nervosa has a prevalence of 1%, it is the second-highest death rate of any mental illness. Roger Cone discusses how melanocortin receptors can be used to treat both obesity and anorexia.
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New strides in Ewing sarcoma research
Patrick Grohar answers questions about symptoms, treatments and research initiatives that are being undertaken with respect to Ewing Sarcoma.
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Misfolded proteins accumulate in the mitochondria of patients with type 2 diabetes
Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding. In a new study, researchers at the University of Michigan found that mitochondria also accumulate misfolded proteins, which kills insulin-producing β-cells of patients with type 2 diabetes.
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How do spaceflights and long term planetary missions affect vision?
Joshua Ong, M.D., resident physician at University of Michigan Kellogg Eye Center answers questions about how spaceflight affects vision and what protective measures astronauts use.
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New clinical trials for pediatric brain tumors
Brain and spinal cord tumors account for one in four childhood cancers. Although 75% of children survive for at least five years after being diagnosed, many patients have recurrent tumors that cannot be cured. Andrea Franson discusses current therapies for pediatric brain tumors, how viruses can be used to target tumor cells and the new phase 1 trial that started in May 2025.
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Treating a rare eye condition in a 7-year-old
Charlotte Dengler was diagnosed with an eye lesion that compromised her vision and underwent surgery at Kellogg to remove the lesion and now her vision is being slowly restored.
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What does Joe Biden’s prostate cancer diagnosis mean for older patients?
Based on former President Joe Biden's recent diagnosis, a Michigan Medicine urologists discusses routine screening procedures and treatment outcomes.