Thomas E Wilson, MD, PhD
Pathology
109 Zina Pitcher Place, Room 2065
Ann Arbor, MI 48109
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About
Thomas E. Wilson, M.D. Ph.D., is a Professor of Pathology and Human Genetics at the University of Michigan Medical School.
Dr. Wilson is a molecular genetic pathologist active in the clinic with related research interests that include basic studies of yeast double-strand break repair, mechanisms of mammalian chromosomal instability, genomic technologies in core facilities, and bioinformatics, including projects aimed at standardizing and sharing data analysis tools.
Education and mentorship of diverse trainees is critical to our mission and Dr. Wilson directs classes and UROP and other research projects related to molecular genetics, translational research, and bioinformatics.
Please visit https://wilsonte-umich.github.io/ learn more about Dr. Wilson's goals to advance understanding of the genetic processes that cause mutations associated with human diseases by detecting them in the clinical laboratory, exploring their mechanisms in the research laboratory, and developing resources to help students and other researchers do the same.
Links
https://wilsonte-umich.github.io/
Qualifications
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ResidencyWashington University in St. Louis School of Medicine, Laboratory Medicine, St Louis, United States
1994 - 1999
Residency
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Postdoctoral FellowWashington University in St. Louis School of Medicine, St Louis, United States
1995 - 1999
Postdoctoral Fellowship
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Chief ResidentWashington University in St. Louis School of Medicine, St Louis, United States
1998 - 1999
Chief Resident
Center Memberships
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Center MemberRogel Cancer Center
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Center MemberCenter for Computational Medicine and Bioinformatics
Recent Publications
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Narayanan IV, Bedi K, Magnuson B, McShane A, Ashaka M, Paulsen M, Wilson TE, Ljungman M. Genome Res, 2026 Mar 26;Journal ArticleIsoform- and pathway-specific regulation of post-transcriptional RNA processing in human cells.
DOI:10.1101/gr.280892.125 PMID: 41887799 -
Kim Y, Cheng W, Cho CS, Hwang Y, Si Y, Park A, Schrank M, Hsu JE, Anacleto A, Xi J, Kim M, Pedersen E, Koues OI, Wilson T, Lee CH, Jun G, Kang HM, Lee JH. Nature Protocols, 2025 Mar 1; 20 (3): 643 - 689.Journal ArticleSeq-Scope: repurposing Illumina sequencing flow cells for high-resolution spatial transcriptomics
DOI:10.1038/s41596-024-01065-0 PMID: 39482362 -
Wilson TE, Ahmed S, Winningham A, Glover TW. Nature Communications, 2024 Dec 1; 15 (1):Journal ArticleReplication stress induces POLQ-mediated structural variant formation throughout common fragile sites after entry into mitosis
DOI:10.1038/s41467-024-53917-8 PMID: 39505880 -
Bedi K, Magnuson B, Narayanan IV, McShane A, Ashaka M, Paulsen MT, Wilson TE, Ljungman M. 2024 Jun 12;PreprintIsoform and pathway-specific regulation of post-transcriptional RNA processing in human cells.
DOI:10.1101/2024.06.12.598705 PMID: 38915566 -
Wilson TE, Ahmed S, Winningham A, Glover TW. 2024 May 31; bioRxiv,PreprintPOLQ mediates replication-stress induced structural variant formation throughout common fragile sites during mitosis
DOI:10.1101/2024.05.28.596214 -
McShane A, Narayanan IV, Paulsen MT, Ashaka M, Blinkiewicz H, Yang NT, Magnuson B, Bedi K, Wilson TE, Ljungman M. 2024 May 3;PreprintCharacterizing nascent transcription patterns of PROMPTs, eRNAs, and readthrough transcripts in the ENCODE4 deeply profiled cell lines.
DOI:10.1101/2024.04.09.588612 PMID: 38645116 -
Laufer VA, Glover TW, Wilson TE. Mutation Research Reviews in Mutation Research, 2023 Jul 1; 792:Journal ArticleApplications of advanced technologies for detecting genomic structural variation
DOI:10.1016/j.mrrev.2023.108475 PMID: 37931775 -
Wilson TE, Ahmed S, Higgins J, Salk JJ, Glover TW. Nar Genomics and Bioinformatics, 2023 Jun 1; 5 (2):Journal ArticlesvCapture: efficient and specific detection of very low frequency structural variant junctions by error-minimized capture sequencing
DOI:10.1093/nargab/lqad042
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Highlighted Publications: August - December 2025
Highlighted Publications - November 2024
