Matthias Kretzler, MD
Warner-Lambert/Parke-Davis Professor of Medicine
Professor of Internal Medicine and Research
Professor, Computational Medicine and Bioinformatics
[email protected]

Available to mentor
Matthias Kretzler, MD
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • PhD
      University of Heidelberg, Heidelberg, 1993
    • MD
      University of Heidelberg, Heidelberg, 1992
    • Baccalaureate
      St. Paulusheim, Bruchsal, 1985
    Center Memberships
    • Center Member
      Biosciences Initiative
    • Center Member
      Precision Health Initiative
    • Center Member
      Global REACH
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Caswell Diabetes Institute
    Research Overview

    Defining the molecular pathophysiology of glomerular disease for function-based disease management in international, multidisciplinary research networks

    Integrative systems biology of renal disease with a focus on glomerular diseases

    Molecular diagnostic and target identification of renal disease

    Links
    • MiKTMC
    Recent Publications See All Publications
    • Journal Article
      Lupus-prone NZM2328 mice exhibit enhanced UV-induced myeloid cell recruitment and activation in a type I interferon dependent manner.
      Maz MP, Reddy AL, Berthier CC, Tsoi LC, Colesa DJ, Wolf SJ, Shi H, Loftus SN, Moallemian R, Bogle R, Kretzler M, Jacob CO, Gudjonsson JE, Kahlenberg JM. J Autoimmun, 2024 Sep 5; 149: 103296 DOI:10.1016/j.jaut.2024.103296
      PMID: 39241536
    • Journal Article
      WNT-dependent interaction between inflammatory fibroblasts and FOLR2+ macrophages promotes fibrosis in chronic kidney disease.
      Cohen C, Mhaidly R, Croizer H, Kieffer Y, Leclere R, Vincent-Salomon A, Robley C, Anglicheau D, Rabant M, Sannier A, Timsit M-O, Eddy S, Kretzler M, Ju W, Mechta-Grigoriou F. Nat Commun, 2024 Jan 25; 15 (1): 743 DOI:10.1038/s41467-024-44886-z
      PMID: 38272907
    • Journal Article
      Increased risk of kidney failure in patients with genetic kidney disorders.
      Elliott MD, Vena N, Marasa M, Cocchi E, Bheda S, Bogyo K, Shang N, Zanoni F, Verbitsky M, Wang C, Kolupaeva V, Jin G, Sofer M, Gras Pena R, Canetta PA, Bomback AS, Guay-Woodford LM, Hou J, Gillespie BW, Robinson BM, Klein JB, Rheault MN, Smoyer WE, Greenbaum LA, Holzman LB, Falk RJ, Parsa A, Sanna-Cherchi S, Mariani LH, Kretzler M, Kiryluk K, Gharavi AG, CureGN Consortium . J Clin Invest, 2024 Sep 3; 134 (17): DOI:10.1172/JCI178573
      PMID: 39225089
    • Journal Article
      Gene Expression Sets and Renal Profiling from the Renal AL Amyloid Involvement and NEOD00 (RAIN) Trial.
      Varga C, Eichinger F, Nair V, Naik AS, Nasr SH, Fogo AB, Toskic D, Kretzler M, Comenzo RL. Kidney Int Rep, 2024 Sep; 9 (9): 2786 - 2797. DOI:10.1016/j.ekir.2024.07.002
      PMID: 39291193
    • Journal Article
      Growth in children with nephrotic syndrome: a post hoc analysis of the NEPTUNE study.
      Maniar A, Gipson DS, Brady T, Srivastava T, Selewski DT, Greenbaum LA, Dell KM, Kaskel F, Massengill S, Tran C, Trachtman H, Lafayette R, Almaani S, Hingorani S, Wang C-S, Reidy K, Cara-Fuentes G, Gbadegesin R, Myers K, Sethna CB, Members of the Nephrotic Syndrome Study Network (NEPTUNE) . Pediatr Nephrol, 2024 Sep; 39 (9): 2691 - 2701. DOI:10.1007/s00467-024-06375-9
      PMID: 38671228
    • Journal Article
      Ontology-based modeling, integration, and analysis of heterogeneous clinical, pathological, and molecular kidney data for precision medicine.
      He YO, Barisoni L, Rosenberg AZ, Robinson PN, Diehl AD, Chen Y, Phuong JP, Hansen J, Herr BW, Börner K, Schaub J, Bonevich N, Arnous G, Boddapati S, Zheng J, Alakwaa F, Sarder P, Duncan WD, Liang C, Valerius MT, Jain S, Iyengar R, Himmelfarb J, Kretzler M, Kidney Precision Medicine Project . bioRxiv, 2024 Aug 4; DOI:10.1101/2024.04.01.587658
      PMID: 38617362
    • Journal Article
      Clinical Trials for Kidney Disease in the Era of Personalized Medicine.
      Heerspink HJL, Kretzler M. J Am Soc Nephrol, 2024 Aug 1; 35 (8): 1123 - 1126. DOI:10.1681/ASN.0000000000000412
      PMID: 39248631
    • Journal Article
      Elevated Exposure to Air Pollutants Accelerates Primary Glomerular Disease Progression.
      Troost JP, D'Souza J, Buxton M, Kshirsagar AV, Engel LS, O'Lenick CR, Smoyer WE, Klein J, Ju W, Eddy S, Helmuth M, Mariani LH, Kretzler M, Trachtman H. Kidney Int Rep, 2024 Aug; 9 (8): 2527 - 2536. DOI:10.1016/j.ekir.2024.05.013
      PMID: 39156153