2276 Medical Science Building ,1301 Catherine St
Ann Arbor, MI 48109
Available to mentor
Robert Koeppe's research interests center around the quantitative aspects of positron emission tomography (PET). Specific research areas include the development and implementation of tracer kinetic models for new and existing positron labeled radiotracers, development of optimal techniques for estimation of physiological quantities, and development and implementation of automated image analysis routines for use with PET. Another specific area of research is the use of PET cerebral blood flow activation studies to examine various cognitive and neurological functions of the brain. Other research interests include the correlation and comparison of information obtained from PET studies to that obtained from corresponding anatomic imaging procedures such as magnetic resonance imaging.
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Landau SM, Lee J, Murphy A, Ward TJ, Harrison TM, Baker SL, DeCarli C, Harvey D, Tosun D, Weiner MW, Koeppe RA, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative . Alzheimers Dement, 2024 Jan 19;Journal ArticleIndividuals with Alzheimer's disease and low tau burden: Characteristics and implications.
DOI:10.1002/alz.13609 PMID: 38241084 -
Shirzadi Z, Schultz SA, Yau W-YW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, Levey AI, Gordon BA, Schofield PR, Salloway SP, Perrin RJ, McDade E, Levin J, Cruchaga C, Allegri RF, Fox NC, Goate A, Day GS, Koeppe R, Chui HC, Berman S, Mori H, Sanchez-Valle R, Lee J-H, Rosa-Neto P, Ruthirakuhan M, Wu C-Y, Swardfager W, Benzinger TLS, Sohrabi HR, Martins RN, Bateman RJ, Johnson KA, Sperling RA, Greenberg SM, Schultz AP, Chhatwal JP, Dominantly Inherited Alzheimer Network and the Alzheimer’s Disease Neuroimaging Initiative . JAMA Neurol, 2023 Dec 1; 80 (12): 1353 - 1363.Journal ArticleEtiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.
DOI:10.1001/jamaneurol.2023.3618 PMID: 37843849 -
Mundada NS, soleimani‐Meigooni DN, Zeltzer E, Windon C, Tanner JA, Heath CL, Iaccarino L, Shankar R, Amuiri A, Aisen PSS, Eloyan A, Koeppe RA, Carrillo MC, Dickerson BC, Apostolova LG, Rabinovici GD, La Joie R. Alzheimer's & Dementia, 2023 Dec; 19 (S16):Journal ArticleAmyloid‐, tau‐, and FDG‐PET in amyloid‐negative patients clinically diagnosed with early‐onset Alzheimer’s disease in the LEADS study
DOI:10.1002/alz.079008 -
Mundada NS, Soleimani‐Meigooni DN, Zeltzer E, Windon C, Tanner JA, Heath CL, Iaccarino L, Shankar R, Amuiri A, Aisen PSS, Eloyan A, Koeppe RA, Carrillo MC, Dickerson BC, Apostolova LG, Rabinovici GD, La Joie R. Alzheimer's & Dementia, 2023 Dec; 19 (S10):Journal ArticleAmyloid‐, tau‐, and FDG‐PET in amyloid‐negative patients clinically diagnosed with early‐onset Alzheimer’s disease in the LEADS study
DOI:10.1002/alz.081864 -
La Joie R, Mundada N, Iaccarino L, soleimani‐Meigooni DN, Zeltzer E, Windon C, Tanner JA, Heath CL, Shankar R, Amuiri A, Cho H, Ackley SF, Blazhenets G, Aisen PSS, Eloyan A, Koeppe RA, Carrillo MC, Dickerson BC, Apostolova LG, Rabinovici GD. Alzheimer's & Dementia, 2023 Dec; 19 (S24):Journal ArticleAmyloid‐PET, tau‐PET, and their association in sporadic early‐onset Alzheimer’s Disease: Cross‐sectional and longitudinal data from the LEADS study
DOI:10.1002/alz.078003 -
Logan PE, Dage JL, Hammers DB, Manchella MK, Eloyan A, Mundada NS, La Joie R, Iaccarino L, Fagan AM, Foroud TM, Zetterberg H, Blennow K, Koeppe RA, Aisen PSS, Carrillo MC, Rabinovici GD, Dickerson BC, Apostolova LG. Alzheimer's & Dementia, 2023 Dec; 19 (S10):Journal ArticleAssociations of plasma GFAP, NfL, and p‐tau231 with early‐onset Alzheimer’s Disease pathology
DOI:10.1002/alz.081616 -
Logan PE, Dage JL, Hammers DB, Manchella MK, Eloyan A, Mundada NS, La Joie R, Iaccarino L, Fagan AM, Foroud TM, Zetterberg H, Blennow K, Koeppe RA, Aisen PSS, Carrillo MC, Rabinovici GD, Dickerson BC, Apostolova LG. Alzheimer's & Dementia, 2023 Dec; 19 (S16):Journal ArticleAssociations of plasma GFAP, NfL, and p‐tau231 with early‐onset Alzheimer’s Disease pathology
DOI:10.1002/alz.073443 -
Lee G, Nho K, Kang B, Sohn K-A, Kim D, Alzheimer’s Disease Neuroimaging Initiative . Sci Rep, 2023 Aug 1; 13 (1): 12466Journal ArticleAuthor Correction: Predicting Alzheimer's disease progression using multi-modal deep learning approach.
DOI:10.1038/s41598-023-39138-x PMID: 37528098