Arul Chinnaiyan, MD, PhD

 Arul Chinnaiyan, MD, PhD
Professor
Email:
[email protected]
Available to mentor
Arul Chinnaiyan, MD, PhD
Arul Chinnaiyan, MD, PhD
Professor
  • Center Memberships
  • Recent Publications

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    • Center Memberships
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Taubman Institute
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Global REACH
    • Center Member
      Rogel Cancer Center
    • Center Member
      Center for Computational Medicine and Bioinformatics

    Recent Publications

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    • Journal Article
      A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR
      Yi Y, Li Y, Wang R, Yu X, Liu Q, Yum C, Zhang Y, Qiao Y, Szczepanski A, Wu S, Li Q, Fazli L, Shen J, Wang X, Li X, Mu P, Schaeffer EM, Hundley HA, Niu H, Chinnaiyan AM, Wang L, Shi J, Jin J, Dong X, Zhao W, Chen K, Cao Q. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-026-71207-3
      PMID: 41882000
    • Journal Article
      Targeting chordoma via an isocitrate dehydrogenase-1-dependent susceptibility to redox metabolism
      Pun M, Deogharkar A, Natarajan SK, Nuechterlein N, Tian W, Ji S, Young E, Yang F, Hawes D, Andren AC, Owen JH, Rau S, Su F, Cao X, Parolia A, Prince M, Fry J, Gardner PA, Yang R, Judkins AR, Koschmann CJ, Venteicher AS, Lyssiotis CA, Chinnaiyan AM, Venneti S. Acta Neuropathologica, 2026 Dec 1; 152 (1): DOI:10.1007/s00401-026-03048-9
      PMID: 42493667
    • Journal Article
      Disentangling the Cellular Composition of FLCN-Mutated Tumors in Birt-Hogg-Dubé Syndrome by Spatial Transcriptomics
      Wang XM, Zhang Y, Mannan R, Zhou J, Wang S, Chinnaiyan AM, Dhanasekaran SM, Mehra R. Modern Pathology, 2026 Nov 1; 39 (11): DOI:10.1016/j.modpat.2026.101083
      PMID: 42754233
    • Journal Article
      Integration-Associated Paraspinal Neoplasm after AAV Gene Therapy.
      Vo JN, Wu Y-M, Heider A, Cao X, Wang R, Pham T, Teo GC, Magge SN, Parmar H, Mody R, Robinson DR, Chinnaiyan AM. N Engl J Med, 2026 Oct 15; 395 (15): 1555 - 1558. DOI:10.1056/NEJMc2607927
      PMID: PMC13671263
    • Preprint
      Lactate epigenetically shapes tumor cell states in H3K27M diffuse midline gliomas
      Lum J, Nuechterlein N, Sliger S, Eyunni S, Tamrazi B, Blüml S, Tian W, Deogharkar A, Sweha SR, Mota M, Bayliss J, Peterson E, Ji S, Wittwer M, Bhat K, Mott BT, Hamanishi ET, Merkuri F, Azambuja A, Conceicao H, Su F, Cao X, Pandey R, Ljare OB, Parolia A, Yadav VN, Wahl DR, Koschmann C, Simoes-Costa M, Pichumani K, Wang S, Chinnaiyan AM, Venneti S. 2026 Oct 8; bioRxiv, DOI:10.64898/2026.10.02.756321
    • Journal Article
      Lysosomal metabolism in pancreatic cancer and its crosstalk with host physiology
      Cheng C, Pakkan R, Chinnaiyan AM, Lyssiotis CA. Genes Development, 2026 Oct 1; 40 (19-20): 1578 - 1597. DOI:10.1101/gad.353702.126
      PMID: 42562573
    • Journal Article
      A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer
      Zheng Y, Cheng C, Cao Y, Cruz G, Zhang Y, Paturu R, Mahapatra S, Hu J, Mannan R, Karabürk H, Bhattacharyya R, Yin Y, Zhao Y, Liu W, Cao X, Xue H, Li C, Wang Z, Miner SJ, Reichert ZR, Mehra R, Vaishampayan U, Sahai V, Weisman LS, Ding K, Lyssiotis CA, Wang Y, Chinnaiyan AM, Qiao Y. Cancer Cell, 2026 Sep 14; 44 (9): 1761 - 1778.e12. DOI:10.1016/j.ccell.2026.07.003
      PMID: 42546705
    • Preprint
      Single-Atom Modification Enables Reversal of Degradation Selectivity between NSD2 and GSPT1
      Shen W, Liu Y, Liu L, Liu Y, Zhang Y, Chen Y, Wang L, Zhou Z, Zhang A, Shen H, Zhou F, Huang W, Ren X, Parolia A, Xu Y, Zhou Y, Wang Z, Chinnaiyan AM, Ding K. 2026 Sep 15; bioRxiv, DOI:10.64898/2026.09.09.750440

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