Andrea D Thompson
Internal Medicine- Division of Cardiovascular Medicine
1150 W. Medical Center Drive, MSRBIII 7220B
Ann Arbor, MI 48109
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About
Andrea D. Thompson, MD/PhD is an Assistant Professor in the Department of Internal Medicine, Division of Cardiovascular Medicine. She received her bachelor’s degree from the Massachusetts Institute of Technology in Cambridge, MA, and her medical degree from the University of Michigan in Ann Arbor, MI. She completed her residency training in Internal Medicine and fellowship training in Cardiovascular Medicine and Critical Care Medicine at the University of Michigan. She joined the faculty in 2022. Dr. Thompson’s clinical work is focused on caring for critically ill cardiac patients in the cardiac intensive care unit. She also sees patients within the inherited cardiomyopathies clinic. She has a particular interest in serving the needs of patients living with genetic cardiomyopathies.
Links
Laboratory Website Google Scholar
Qualifications
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Critical Care MedicineMichigan Medicine, Ann Arbor, United States
2021 - 2022
Clinical Fellowship
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Hypertrophic cardiomyopathy ResearchMichigan Medicine, Ann Arbor, United States
2019 - 2021
Postdoctoral Research
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Cardiovascular DiseaseMichigan Medicine, Ann Arbor, United States
2016 - 2020
Clinical Fellowship
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Internal MedicineMichigan Medicine, Ann Arbor, United States
2014 - 2016
Residency
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MDUniversity of Michigan Medical School, Ann Arbor, MI, United States
2006 - 2014
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PhD- Chemical BiologyUniversity of Michigan, Ann Arbor, MI, United States
2006 - 2014
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BS - Chemical EngineeringMassachusetts Institute of Technology, Cambridge, MA, United States
2002 - 2006
Center Memberships
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberFrankel Institute for Heart and Brain Health
Research Overview
Dr. Thompson’s research interests include basic and translational research focused on cardiomyopathies. This includes:
1. Identifying modifiers of disease onset and progression in cardiomyopathies.
2. Uncovering novel disease modifying targets and developing small molecules to treat cardiomyopathies.
3. Defining the molecular mechanisms by which MYBPC3 missense variants lead to hypertrophic cardiomyopathy.
4. Developing strategies to better understand and characterize variants of uncertain significance.
5. Understanding biological pathways which drive recovery after cardiogenic shock.
Recent Publications
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VARSHNEY AS, PALAZZOLO MG, BARNETT CF, BOHULA EA, BURKE JA, CHAUDHRY SP, CHONDE MD, GHAFGHAZI S, GERBER DA, KENIGSBERG B, KONTOS MC, KWON Y, LAWLER PR, LORIAUX DB, MENON VENU, MILLER PE, O'BRIEN CG, PAPOLOS AI, PATEL SM, POTTER BJ, PRASAD R, SHAH KS, SINHA SS, SOLOMON MA, THOMPSON A, TEUTEBERG JJ, VAN DIEPEN SEAN, MORROW DA, BERG DD. Journal of Cardiac Failure, 2025 Oct 1; 31 (10): 1512 - 1522.Journal ArticleEpidemiology and Prognostic Significance of Acute Noncardiac Organ Dysfunction Across Cardiogenic Shock Subtypes
DOI:10.1016/j.cardfail.2024.12.017 PMID: 40015594 -
FEINMAN J, TOMEY MI, PALAZZOLO MG, MARTILLO M, RONQUILLO M, MOSS NOAH, SERRAO G, BOHULA EA, BERG DD, DIEPEN SV, KATZ JN, CHONDE MD, CHAUDHRY SP, GEORGE AJ, GERBER D, GOLDFARB MJ, KELLER NM, KONTOS MC, LORIAUX DB, O'BRIEN CG, PISANI BA, PROUDFOOT A, SIDHU K, SINHA SS, SRIDHARAN L, TAPASKAR N, THOMAS A, THOMPSON AD, MORROW DA, GIDWANI U, LEIBNER EVAN. Journal of Cardiac Failure, 2025 Jun 1; 31 (6): 961 - 966.Journal ArticleDifferences Between Ischemic and Nonischemic Cardiomyopathy in Heart Failure Related Cardiogenic Shock
DOI:10.1016/j.cardfail.2025.01.020 PMID: 40021044 -
Pankiewicz C, Lilienthal U, Thompson A. 2025 Apr 8;Proceeding / Abstract / PosterTurbo-Flag-MYBPC3 normally localizes to the sarcomere, enabling proximity labeling experiments to evaluate the effect of pathogenic missense variants within the sarcomere.
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Hamilton D, Shriver JL, Park J-G, Michos Z, Ketcham SW, Adie SK, Mathis MR, Patel SM, Morrow DA, Thompson A. 2024 Nov 16;Proceeding / Abstract / PosterVariation in Vasoactive Treatments for Cardiogenic Shock: Insights from the Critical Care Cardiology Trials Network
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Balgobind A, Pierce M, Alviar C, Barnett C, Barsness G, Chaudhry SP, Chonde M, Cooper H, Daniels L, Gidwani U, Fordyce C, Goldfarb M, Katz JN, Kontos M, Kwon Y, Liebner E, Liu S, Miller PE, Newby LK, O'Brien C, Papolos A, Pisani B, Potter B, Proudfoot A, Roswell RO, Sinha SS, Smith TD, Thompson AD, van Diepen S, Zakaria S, Morrow D, Villela MA. American Heart Journal, 2024 Oct 1; 276: 115 - 119.Journal ArticleCurrent practices in the management of temporary mechanical circulatory support: A survey of CICU directors in North America
DOI:10.1016/j.ahj.2024.05.018 PMID: 39182940 -
Berg DD, Bohula EA, Patel SM, Alfonso CE, Alviar CL, Baird-Zars VM, Barnett CF, Barsness GW, Bennett CE, Chaudhry SP, Fordyce CB, Ghafghazi S, Gidwani UK, Goldfarb MJ, Katz JN, Menon V, Miller PE, Newby LK, Papolos AI, Park JG, Pierce MJ, Proudfoot AG, Sinha SS, Sridharan L, Thompson AD, Van Diepen S, Morrow DA. European Heart Journal Acute Cardiovascular Care, 2024 Oct 1; 13 (10): 709 - 714.Journal ArticleEpidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions
DOI:10.1093/ehjacc/zuae098 PMID: 39208447 -
Patel SM, Berg DD, Bohula EA, Baird-Zars VM, Park JG, Barnett CF, Daniels LB, Fordyce CB, Ghafghazi S, Goldfarb MJ, Gorder K, Kwon Y, Leibner E, Menon V, Potter BJ, Prasad R, Solomon MA, Teuteberg JJ, Thompson AD, Zakaria S, Katz JN, van Diepen S, Morrow DA. Jacc Heart Failure, 2024 Sep 1; 12 (9): 1625 - 1635.Journal ArticleContinuum of Preshock to Classic Cardiogenic Shock in the Critical Care Cardiology Trials Network Registry
DOI:10.1016/j.jchf.2024.06.009 PMID: 39093257 -
Thompson A, Christopher M, Nichols S, Yob J, Lilienthal U, Day SM. 2024 Jun 23;Proceeding / Abstract / PosterMissense variants in Myosin Binding Protein C in Human HCM and a New Mouse Model.
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