Andrea D Thompson

 profile-andrea-thompson-2020
Assistant Professor
Office:
University of Michigan
Internal Medicine- Division of Cardiovascular Medicine
1150 W. Medical Center Drive, MSRBIII 7220B
Ann Arbor, MI 48109
Email:
[email protected]
Available to mentor
Andrea D Thompson
profile-andrea-thompson-2020
Assistant Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • About

    Andrea D. Thompson, MD/PhD is an Assistant Professor in the Department of Internal Medicine, Division of Cardiovascular Medicine. She received her bachelor’s degree from the Massachusetts Institute of Technology in Cambridge, MA, and her medical degree from the University of Michigan in Ann Arbor, MI. She completed her residency training in Internal Medicine and fellowship training in Cardiovascular Medicine and Critical Care Medicine at the University of Michigan. She joined the faculty in 2022. Dr. Thompson’s clinical work is focused on caring for critically ill cardiac patients in the cardiac intensive care unit. She also sees patients within the inherited cardiomyopathies clinic. She has a particular interest in serving the needs of patients living with genetic cardiomyopathies.

    Links
    • Laboratory Website
    • Google Scholar

    Qualifications
    • Critical Care Medicine
      Michigan Medicine, Ann Arbor, United States
      2021 - 2022
      Clinical Fellowship
    • Hypertrophic cardiomyopathy Research
      Michigan Medicine, Ann Arbor, United States
      2019 - 2021
      Postdoctoral Research
    • Cardiovascular Disease
      Michigan Medicine, Ann Arbor, United States
      2016 - 2020
      Clinical Fellowship
    • Internal Medicine
      Michigan Medicine, Ann Arbor, United States
      2014 - 2016
      Residency
    • MD
      University of Michigan Medical School, Ann Arbor, MI, United States
      2006 - 2014
    • PhD- Chemical Biology
      University of Michigan, Ann Arbor, MI, United States
      2006 - 2014
    • BS - Chemical Engineering
      Massachusetts Institute of Technology, Cambridge, MA, United States
      2002 - 2006

    Center Memberships
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      Frankel Institute for Heart and Brain Health

    Research Overview

    Dr. Thompson’s research interests include basic and translational research focused on cardiomyopathies. This includes:

    1. Identifying modifiers of disease onset and progression in cardiomyopathies.

    2. Uncovering novel disease modifying targets and developing small molecules to treat cardiomyopathies.

    3. Defining the molecular mechanisms by which MYBPC3 missense variants lead to hypertrophic cardiomyopathy.

    4. Developing strategies to better understand and characterize variants of uncertain significance.

    5. Understanding biological pathways which drive recovery after cardiogenic shock.

    Recent Publications

     See All Publications
    • Journal Article
      Variation in Vasoactive Treatment Selection for Cardiogenic Shock: Insights From the Critical Care Cardiology Trials Network (CCCTN).
      Hamilton DE, Shriver JL, Patel SM, Park J-G, Michos ZE, Mathis MR, Adie SK, Alviar CL, Barnett CF, Berg DD, Bennett CE, Bohula EA, Carnicelli AP, Daniels LB, Dodson MW, Gage A, Gidwani U, Goldfarb M, Katz JN, Ketcham SW, Kwon Y, Leibner ES, Loriaux DB, Luk A, Marano P, Miller PE, Mukundan SV, Papolos AI, Pisani BA, Proudfoot AG, Roswell RO, Shah KS, Solomon MA, Tomey MI, van Diepen S, Zakaria S, Morrow DA, Thompson AD, CCCTN Investigators . Circ Heart Fail, 2026 Sep; 19 (9): e013778 DOI:10.1161/CIRCHEARTFAILURE.125.013778
      PMID: PMC13240787
    • Preprint
      Pathogenic MYBPC3 missense variants alter protein-protein interactions within the sarcomere.
      Thompson AD, Pankiewicz C, Plenge LS, Lilienthal U, Kotaru S, Vignesh M, Phan T, McAllister C, Yob J, Morley MP, Ingles J, Hespe S, Helms AS, Ginsburg D, SHaRe-HCM Investigators , Day SM. 2026 Jul 20; DOI:10.64898/2026.05.27.727676
      PMID: 42327163
    • Journal Article
      Charting new territories in cardiac care intensive care rehabilitation and the enduring impact on post-acute cardiac event outcomes
      Thompson AD, Nguyen K, Alhuneafat L, Elliott AM. European Heart Journal Acute Cardiovascular Care, 2026 Jun 1; 15 (6): 484 - 493. DOI:10.1093/ehjacc/zuag070
      PMID: 42160216
    • Journal Article
      Post-CICU Recovery Programs
      Nguyen K, Dudzinski DM, Dahiya G, Elliott A, Hillerson DB, Isseh I, Thompson AD, Whiteside HL, Sinha SS. Jacc Advances, 2026 Apr 1; 5 (4): DOI:10.1016/j.jacadv.2026.102652
    • Presentation
      MYBPC3 as a therapeutic target in HCM.
      Thompson A. 2026 Jul 21;
    • Presentation
      Defining the molecular mechanisms of MYBPC3 pathogenic missense variants
      Thompson A. 2026 Jul 21;
    • Presentation
      Defining the Molecular Mechanisms of MYBPC3 pathogenic missense variants.
      Thompson A, McAllister C, Turner K. 2026 Jul 21;
    • Presentation
      Defining the Molecular Mechanisms of MYBPC3 pathogenic missense variants.
      Thompson A, McAllister C, Turner K. 2026 Jul 21;

    Featured News & Stories

         Frankel IHBH M-BoCA Awardees
    Research News

    Innovative Multidisciplinary Research Pilot Award FY 25 Recipients

    The Stanley and Judith Frankel Institute for Heart and Brain Health and the Michigan-Biology of Cardiac Aging (M-BoCA) program of the Frankel Cardiovascular Center, are delighted to announce the recipients of this year's Innovative Multidisciplinary Research Pilot Award.