Recent Publications

Explore the latest publications from our labs.

New State-of-the-Art Review Published in The British Medical Journal

Antiphospholipid Syndrome: Advances in Diagnosis, Pathogenesis, and Management

Authors: Jason S. Knight, D. Ware Branch, Thomas L. Ortel

Prothrombotic Autoantibodies in Serum from Patients Hospitalized with COVID-19

Prothrombotic Autoantibodies in Serum from Patients Hospitalized with COVID-19, published in Science Translational Medicine in November 2020, has been featured in over 110 news outlets.

Recent Publications


Non-Criteria Antiphospholipid Antibodies and Calprotectin as Potential Biomarkers in Pediatric Antiphospholipid Syndrome Elizabeth E. Sloan, Katarina Kmetova, Somanathapura K. NaveenKumar, Lyndsay Kluge, Emily Chong, Claire K. Hoy, Srilakshmi Yalavarthi, Cyrus Sarosh, Jeanine Baisch, Lynnette Walters, Lorien Nassi, Julie Fuller, Jessica L. Turnier, Virginia Pascual, Tracey B. Wright, Jacqueline A. Madison, Jason S. Knight, Ayesha Zia, Yu Zuo. Clinical Immunology. April 2024

Low Ectonucleotidase Activity and Increased Neutrophil-Platelet Aggregates in Patients with Antiphospholipid Syndrome Somanathapura K. NaveenKumar, Ajay Tambralli, Bruna Mazetto Fonseca, Srilakshmi Yalavarthi, Wenying Liang, Claire K. Hoy, Cyrus Sarosh, Christine E. Rysenga, Caroline H. Ranger, Caroline E. Vance, Jacqueline A. Madison, Fernanda A. Orsi, Suman L. Sood, Jordan K. Schaefer, Yu Zuo, Jason S. Knight. Blood. March 21, 2024

Longitudinal Plasma Proteomics in CAR T–Cell Therapy Patients Implicates Neutrophils and NETosis in the Genesis of CRS Christopher Flora, Mary Olesnavich, Yu Zuo, Erin Sandford, Rashmi Madhukar, Michelle Rozwadowski, Kavya Sugur, Andrew Ly, Ata Alpay Canbaz, Audra Shedeck, Gen Li, Marcus J. Geer, Gregory A. Yanik, Monalisa Ghosh, David G. Frame, Challice L. Bonifant, Tania Jain, Jason S. Knight, Sung Won Choi, Muneesh Tewari. Blood Advances. March 14, 2024

Calprotectin Impairs Platelet Survival in Patients with Primary Antiphospholipid Syndrome Claire K. Hoy, Somanathapura K. NaveenKumar, Sherwin A. Navaz, Kavya Sugur, Srilakshmi Yalavarthi, Cyrus Sarosh, Tristin Smith, Katarina Kmetova, Emily Chong, Noah F. Peters, Christine E. Rysenga, Gary L. Norman, Gabriel Figueroa-Parra, Dava Nelson, Jennifer Girard, Asra Z. Ahmed, Jordan K. Schaefer, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Jason S. Knight, Cynthia S. Crowson, Alí Duarte-García, Yu Zuo. Arthritis & Rheumatology. January 16, 2024

Non-Pharmacological Rehabilitation Interventions for Individuals with Antiphospholipid Syndrome: A Scoping Review
Alexandra E Harper, Yen T Chen, Stephanie Tancer, Kyla R Rodgers, Amber D Crumb, Whitney A Townsend, Jason S Knight, Susan L Murphy. Lupus. December 19, 2023

Inhibition of Neutrophil Extracellular Trap Formation Alleviates Vascular Dysfunction in Type 1 Diabetic Mice
Chao Liu, Srilakshmi Yalavarthi, Ajay Tambralli, Lixia Zeng, Christine E Rysenga, Nikoo Alizadeh, Lucas Hudgins, Wenying Liang, Somanathapura K NaveenKumar, Hui Shi, Miriam A Shelef, Kevin B Atkins, Subramaniam Pennathur, Jason S Knight. Science Advances. October 25, 2023

Taxifolin Inhibits NETosis Through Activation of Nrf2 and Provides Protective Effects in Models of Lupus and Antiphospholipid Syndrome
Christine E Rysenga, Linda May-Zhang, Miela Zahavi, Jason S Knight, Ramadan A Ali. Rheumatology (Oxford Academic). October 10, 2023

Interaction of the Antiphospholipid Syndrome Autoantigen Beta-2 Glycoprotein I with DNA and Neutrophil Extracellular Traps
Katarína Kmeťová, Elena Lonina, Srilakshmi Yalavarthi, Jerrold S Levine, Claire K Hoy, Cyrus Sarosh, Kelsey Gockman, Alexandra E Morris, Ajay Tambralli, Jacqueline A Madison, Yu Zuo, Rebecca Subang, Joyce Rauch, Jason S Knight. Clinical Immunology. October, 2023

Ginger Intake Suppresses Neutrophil Extracellular Trap Formation in Autoimmune Mice and Healthy Humans
Ramadan A. Ali, Valerie C. Minarchick, Miela Zahavi, Christine E. Rysenga, Kristin A. Sturm, Claire K. Hoy, Cyrus Sarosh, Jason S. Knight, and M. Kristen Demoruelle. JCI Insight. September 22, 2023

Associations Among Antiphospholipid Antibody Types, Isotypes, and Titers: An AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Study
Elena Gkrouzman, Rohan Willis, Danieli Andrade, Maria G Tektonidou, Vittorio Pengo, Guillermo Ruiz-Irastorza, H Michael Belmont, Paul R Fortin, Maria Gerosa, Flavio Signorelli, Tatsuya Atsumi, D Ware Branch, Cecilia Nalli, Esther Rodriguez-Almaraz, Michelle A Petri, Ricard Cervera, Jason S Knight, Maria Efthymiou, Hannah Cohen, Maria Laura Bertolaccini, Doruk Erkan, Robert Roubey, on behalf of APS ACTION. Laboratory Investigation. April 10, 2023