2024

Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study

Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions

Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study

Preferences of Patients with Amyotrophic Lateral Sclerosis for Intrathecal Drug Delivery: Choosing between an Implanted Drug-Delivery Device and Therapeutic Lumbar Puncture

Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort

Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis

2023

The amyotrophic lateral sclerosis exposome: recent advances and future directions

Cumulative Genetic Score and C9orf72 Repeat Status Independently Contribute to Amyotrophic Lateral Sclerosis Risk in 2 Case-Control Studies

Engineered extracellular matrices facilitate brain organoids from human pluripotent stem cells

Causes of death among United States decedents with ALS: An eye toward delaying mortality

A roadmap to ALS prevention: strategies and priorities

Body mass index associates with amyotrophic lateral sclerosis survival and metabolomic profiles

miRNA analysis reveals novel dysregulated pathways in amyotrophic lateral sclerosis

A revision to the United States national ALS registry's algorithm to improve Case-Ascertainment

Occupational history associates with ALS survival and onset segment

2022

Amyotrophic lateral sclerosis

Monoclonal antibody-mediated immunosuppression enables long-term survival of transplanted human neural stem cells in mouse brain

Associations of self-reported occupational exposures and settings to ALS: a case-control study

Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial

Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis

Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis

Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis

Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts

2021

Extracellular Vesicles in Serum and Central Nervous System Tissues Contain microRNA Signatures in Sporadic Amyotrophic Lateral Sclerosis

Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis

Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact

NK cells associate with ALS in a sex- and age-dependent manner

Amyotrophic Lateral Sclerosis Survival Associates With Neutrophils in a Sex-specific Manner

Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial

Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis

2020

A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS

Untargeted metabolomics yields insight into ALS disease mechanisms

The NEALS primary lateral sclerosis registry

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis

A 2020 centenary perspective on neuromuscular disorders

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

Early life metal dysregulation in amyotrophic lateral sclerosis

Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis

Voicing the need for amyotrophic lateral sclerosis environmental research

2019

Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity

Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice

ALS/SURV: a modification of the CAFS statistic

Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials

Lack of consensus in ALS genetic testing practices and divergent views between ALS clinicians and patients

High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis

2018

Abnormal RNA stability in amyotrophic lateral sclerosis

Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization

ALS specific quality of life- short form (ALSSQOL-SF): A brief, reliable and valid version of the ALSSQOL-R

Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Emerging understanding of the genotype-phenotype relationship in amyotrophic lateral sclerosis

Symptom management in amyotrophic lateral sclerosis: We can do better

2017

Complete hazard ranking to analyze right-censored data: An ALS survival study

Best practices protocol for the evaluation of bulbar dysfunction: summary recommendations from the NEALS bulbar subcommittee symposium

Correlation of peripheral immunity with rapid amyotrophic lateral sclerosis progression

Diagnosis and clinical management of amyotrophic lateral sclerosis and other motor neuron disorders

Use of angle-independent M-mode sonography for assessment of diaphragm displacement

Speckle tracking as a method to measure hemidiaphragm excursion

2016

Intraspinal stem cell transplantation for amyotrophic lateral sclerosis: Ready for efficacy clinical trials?

Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials

Increased ratio of circulating neutrophils to monocytes in amyotrophic lateral sclerosis

Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci

Association of environmental toxins with amyotrophic lateral sclerosis

Pearls & Oy-sters: The importance of atypical features and tracking progression in patients misdiagnosed with ALS

2015

Clinical trials of therapies for amyotrophic lateral sclerosis: one size does not fit all

Environmental risk factors and amyotrophic lateral sclerosis (ALS): A case-control study of ALS in Michigan

Dose escalation and safety study of human spinal cord derived neural stem cell transplantation for the treatment of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era

Histological bulbar manifestations in the ALS rat

The spectrum of motor neuron diseases: From childhood spinal muscular atrophy to adult amyotrophic lateral sclerosis

Recent advances and the future of stem cell therapies in amyotrophic lateral sclerosis

The dual roles of immunity in ALS: injury overrides protection

Autocrine production of IGF-I increases stem cell-mediated neuroprotection