ALS Center of Excellence
Leading the fight against ALS.
als

About

Learn about the ALS Center of Excellence.

Pranger ALS Clinic

See where our clinical research and care take place.

Research

Learn about our groundbreaking ALS research.

GIVING

Support ALS research and clinical care.

People

Get to know the people behind the Center.

NEURONETWORK

Learn about the hub of our basic science research.

Making ALS a Preventable Disease

A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.  

We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease. 

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what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death. 

Scott Matzka dropping the puck at the IceALS game Impact
70%
ALS incidence is predicted to rise globally by 2040.
2X
Veterans are more likely to have ALS than others.
90%
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
clinical_studies
Clinical Trials & Observational Studies

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Groundbreaking Basic Science Research

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ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

NEWS & EVENTS
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Health Lab
ALS survival may be cut short by living in disadvantaged communities 
Living in a disadvantaged community may decrease the length of time a person can survive with ALS by over 30%, a Michigan Medicine-led study finds.
Research News
Making ALS Livable for Patients Worldwide
In one of the world’s leading journals, The Lancet Neurology, Drs. Eva Feldman and Stephen Goutman join key international neurologists to publish recommendations based on new models of research, collaboration, and funding that could transform ALS into a livable condition for patients globally.
Proposed reimagining of an ALS Research and care network using the hub and spoke model.  The graphic shows a map of the United States showing the hubs (ALS Centers of Excellence) and spokes (regional and local ALS care centers)
Research News
Reimagining ALS Research & Care
Eva L. Feldman, M.D., Ph.D., published a “Viewpoint” in JAMA Neurology that advocates for a new model to improve ALS research and care.
Research News
ALS Research Gets Over 100 Media Hits in 2024
Our ALS research was convered over 100 times by media outlets across the globe in 2024.
older man sitting in a wheelchair with his back to us outside in fall with a pile of leaves on the ground
Research News
Epigenetic age acceleration associates with a poorer amyotrophic lateral sclerosis survival
Researchers found that participants with ALS who had an older biological age compared to their chronological age had shorter survival; the findings were most pronounced in males and those in high-risk occupations.
Research News
June Park, Ph.D.
The NeuroNetwork for Emerging Therapies welcomes a new postdoctoral fellow specializing in biostatistics.