ALS Center of Excellence
Leading the fight against ALS.
als

About

Learn about the ALS Center of Excellence.

Pranger ALS Clinic

See where our clinical research and care take place.

Research

Learn about our groundbreaking ALS research.

GIVING

Support ALS research and clinical care.

People

Get to know the people behind the Center.

NEURONETWORK

Learn about the hub of our basic science research.

Making ALS a Preventable Disease

A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.  

We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease. 

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what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death. 

Scott Matzka dropping the puck at the IceALS game Impact
70%
ALS incidence is predicted to rise globally by 2040.
2X
Veterans are more likely to have ALS than others.
90%
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
clinical_studies
Clinical Trials & Observational Studies

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Groundbreaking Basic Science Research

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ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

NEWS & EVENTS
See All photo of Dr. Eva Feldman
Research News
Dr. Feldman Featured by ANA
The American Neurological Association highlighted Eva L. Feldman, M.D., Ph.D.’s, past tenure as president.
Research News
How Metabolism Changes in ALS
Researcher observed that changes in metabolism was linked to ALS progression.
Research News
New Members Join ALS Center of Excellence National Advisory Board
Five new board members share a personal experience with ALS and a commitment to advancing care and research for the devastating disease.
brain drawn
Health Lab
ALS survival may be cut short by living in disadvantaged communities 
Living in a disadvantaged community may decrease the length of time a person can survive with ALS by over 30%, a Michigan Medicine-led study finds.
Research News
Making ALS Livable for Patients Worldwide
In one of the world’s leading journals, The Lancet Neurology, Drs. Eva Feldman and Stephen Goutman join key international neurologists to publish recommendations based on new models of research, collaboration, and funding that could transform ALS into a livable condition for patients globally.
Proposed reimagining of an ALS Research and care network using the hub and spoke model.  The graphic shows a map of the United States showing the hubs (ALS Centers of Excellence) and spokes (regional and local ALS care centers)
Research News
Reimagining ALS Research & Care
Eva L. Feldman, M.D., Ph.D., published a “Viewpoint” in JAMA Neurology that advocates for a new model to improve ALS research and care.