ALS Center of Excellence
Leading the fight against ALS.


Learn about the ALS Center of Excellence.

Pranger ALS Clinic

See where our clinical research and care take place.


Learn about our groundbreaking ALS research.


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Get to know the people behind the Center.


Learn about the hub of our basic science research.

Making ALS a Preventable Disease

A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.  

We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease. 

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what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death. 

Scott Matzka dropping the puck at the IceALS game Impact
ALS incidence is predicted to rise globally by 2040.
Veterans are more likely to have ALS than others.
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
Clinical Trials & Observational Studies

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Groundbreaking Basic Science Research

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ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

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Health Lab
Chemicals stored in home garages linked to ALS risk
A Michigan Medicine study finds that storing chemicals in a garage at home may associate with an increased risk of ALS.
Older man swings a golf club with sunset in the background
Health Lab
Recreational activities such as golfing, gardening may be associated with increased ALS risk among men
Participation in recreational activities — including golfing, gardening or yard work, woodworking and hunting — may be associated with an increase in a person’s risk for developing amyotrophic lateral sclerosis, or ALS
Research News
Dr. Feldman at Distinguished Professor Lecture Series
Last year, Dr. Eva Feldman was named the James W. Albers Distinguished University Professor, the University of Michigan’s highest faculty honor. Dr. Feldman chose to name hers after her longtime friend and mentor, Dr. James Albers, U-M Professor Emeritus of Neurology, Psychiatry, and Physical Medicine and Rehabilitation.
Research News
Mini Symposium Series: Environment, Health & Policy
In our latest installment, U.S. Rep. Debbie Dingell sat down to talk to Dr. Eva Feldman about the environment, health, and public policy. Afterward, Dr. Feldman was joined by two esteemed panelists, Drs. Bhramar Mukherjee and Barry Rabe for a live Q&A.
Research News
Drawing a tube of blood could assess ALS risk from environmental toxin exposure
Over the last decade, research at Michigan Medicine has shown how exposure to toxins in the environment, such as pesticides and carcinogenic PCBs, affect the risk of developing and dying from amyotrophic lateral sclerosis.
Research News
Gut Microbiome Provides New Therapeutic Target for ALS
Brain, one of the top academic journals, published groundbreaking new research by Dr. Feldman et al. that looked at the connection between the microbiome, fatty acids in the blood, and ALS.
Women Defining Themselves
The University of Michigan School of Dance is producing a special evening of dance, music, and song to raise awareness for ALS. The performances on May 11 are inspired by a dance you contracted ALS at a young age.
A photo of a female danger