ALS Center of Excellence
Leading the fight against ALS.
als

About

Learn about the ALS Center of Excellence.

Pranger ALS Clinic

See where our clinical research and care take place.

Research

Learn about our groundbreaking ALS research.

GIVING

Support ALS research and clinical care.

People

Get to know the people behind the Center.

NEURONETWORK

Learn about the hub of our basic science research.

Making ALS a Preventable Disease

A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.  

We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease. 

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what is als

Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death. 

Scott Matzka dropping the puck at the IceALS game Impact
70%
ALS incidence is predicted to rise globally by 2040.
2X
Veterans are more likely to have ALS than others.
90%
Of cases occur without family history.
2.4 Years
Life Expectancy After Diagnosis.
clinical_studies
Clinical Trials & Observational Studies

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als
Groundbreaking Basic Science Research

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ALS Center for Excellence
Pranger ALS Clinic

The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.

NEWS & EVENTS
See All older man sitting in a wheelchair with his back to us outside in fall with a pile of leaves on the ground
Research News
Epigenetic age acceleration associates with a poorer amyotrophic lateral sclerosis survival
Researchers found that participants with ALS who had an older biological age compared to their chronological age had shorter survival; the findings were most pronounced in males and those in high-risk occupations.
Research News
June Park, Ph.D.
The NeuroNetwork for Emerging Therapies welcomes a new postdoctoral fellow specializing in biostatistics.
photo of Dr. Eva Feldman
Research News
Dr. Feldman Named to Department of Neurosurgery
The Department of Neurosurgery announced that Eva Feldman, M.D., Ph.D., would receive a joint appointment as a Professor of Neurosurgery.
Her ALS Story 2023 Retreat in Cape Cod
Research News
Her ALS Story
A 27-year-old University of Michigan alumna turned an ALS diagnosis into an opportunity to create a community of support for those like her—young women faced with the deadly disease.
blood vial
Health Lab
ALS diagnosis and survival linked to metals in blood, urine
People with higher levels of metals found in their blood and urine may be more likely to be diagnosed with — and die from — amyotrophic lateral sclerosis, or ALS, a University of Michigan-led study suggests.
Brain Ponderings logo that features a brain drawing with different sections in different colors and a serif font
Research News
Brain Ponderings podcast features Dr. Feldman
Eva Feldman, M.D., Ph.D., sat down with Mark Mattson, Ph.D., Adjunct Professor of Neurology at Johns Hopkins, for his podcase Brain Ponderings to discuss the importance of research on the exposome in neurologic disease.