More articles about: Transgenic Animal Model Core

To celebrate the arrival of the PacBio Revio system in the BRCF Advanced Genomics Core and the BRCF Transgenic Animal Model Core are hosting a PacBio Long-Read Sequencing Workshop. Join U-M researchers and PacBio experts for a day focused on real-world HiFi sequencing applications, bioinformatics, and emerging long-read workflows.

Staff from the BRCF Transgenic Animal Model Core and Advanced Genomics Core used a novel CRISPR/Cas9-based PureTarget enrichment and high-throughput PacBio sequencing method to efficiently and accurately validate genetically modified animal models, a breakthrough recently featured by PacBio and presented at the ASHG annual meeting, highlighting the cores’ innovative contributions to translational research technology.

The BRCF Transgenic Animal Model Core (TAMC) has launched TransgeneFinder, a next-generation sequencing service that uses Oxford Nanopore and PacBio long-read technologies to precisely identify transgene insertion sites and analyze transgene structures in genome-edited animals and cell lines. To celebrate, TAMC is offering a Core Lab Grant Program awarding one free TransgeneFinder characterization to an investigator who submits a brief abstract about their animal model by October 15, 2025; the winner will be announced on November 3, 2025.

Several Cores that are part of the Biomedical Research Core Facilities (BRCF) will be closed or have adjusted hours for the upcoming Memorial Day holiday.