Jordan Shavit, MD, PhD

Henry and Mala Dorfman Family Professor of Pediatric Hematology/Oncology

Professor of Pediatrics

Professor of Human Genetics

Medical School and Program Associate, Frankel CVC Admin

Email:

[email protected]

Available to mentor

Jordan Shavit, MD, PhD

Professor

Qualifications

Center Memberships

Links

Recent Publications

Manage Your Profile

Qualifications

PhD
Northwestern University, Evanston, IL, United States
1994 - 2000

MD
Northwestern University Medical School, Evanston, IL, United States
1992 - 2000

Center Memberships

Center Member
AI and Digital Health Innovation
Center Member
Frankel Institute for Heart and Brain Health
Center Member
Center for Cell Plasticity and Organ Design
Center Member
Samuel and Jean Frankel Cardiovascular Center
Center Member
Rogel Cancer Center

Recent Publications

See All Publications

Journal Article
SGLT1/2 inhibitor sotagliflozin, but not SGLT2-selective inhibitor empagliflozin, attenuates platelet activation and thrombosis.
Stanger L, Goerger K, Zhang X, Yalavarthi P, Rickenberg A, Yamaguchi A, Flores Nascimento M, Kilgore A, Kim H, Wu X, Guo Y, Dahlgren AR, Zhang J, Shavit JA, Pitt B, Chen YE, Holinstat M. J Clin Invest, 2026 Oct 13; DOI:10.1172/JCI201899
PMID: 42873976
Journal Article
The thrombin receptor PAR1 is activated during mouse megakaryopoiesis.
Frankfurter MT, Tang AT, Zhang Z, Yang J, Narayan S, Nguyen E, Li L, Mericko-Ishizuka P, Chen M, Dahlgren AR, Senis YA, Traynelis SF, Outtz Reed H, Shavit JA, Kahn ML. Blood Adv, 2026 Oct 7; DOI:10.1182/bloodadvances.2026021537
PMID: 42843320
Journal Article
OC 03.4 Impaired Cellular Trafficking of a Novel Thrombomodulin Mutant Results in Severe Bleeding, Thrombosis, and Atypical HUS
Lapping-Carr G, Gemel J, Dahlgren A, Shavit J, Beyer E. Research and Practice in Thrombosis and Haemostasis, 2026 Oct 7; 10: 103477 DOI:10.1016/j.rpth.2026.103477
Journal Article
OC 38.5 The roles of the B domain in cargo receptor-dependent secretion of factor V and factor VIII
Zhang B, Srivastava V, Zhang Y, Richter C, Shavit J. Research and Practice in Thrombosis and Haemostasis, 2026 Oct 6; 10: 103653 DOI:10.1016/j.rpth.2026.103653
Journal Article
PB1135 Thrombomodulin deficiency in zebrafish impacts both anti- and procoagulant properties
Dahlgren A, Zhao Y, Grzegorski S, Pontius MHH, Shavit J. Research and Practice in Thrombosis and Haemostasis, 2026 Oct 6; 10: 103997 DOI:10.1016/j.rpth.2026.103997
Journal Article
PB3005 FDA-drug repurposing studies in zebrafish reveal potential novel antidotes for superwarfarin toxicity
Pawar A, Sundaram N, Jacob V, Shavit J. Research and Practice in Thrombosis and Haemostasis, 2026 Oct 6; 10: 105625 DOI:10.1016/j.rpth.2026.105625
Journal Article
Impaired cellular trafficking of a thrombomodulin mutant causes severe bleeding, thrombosis, and atypical hemolytic uremic syndrome
Gemel J, Barnawi Z, Dahlgren AR, Chang A, Hashmat S, Shavit JA, Lapping-Carr G, Beyer EC. Blood Vessels Thrombosis and Hemostasis, 2026 Aug 1; 3 (3): DOI:10.1016/j.bvth.2026.100182
Preprint
A sensitized model of thrombosis validates known multigenic relationships and suggests novel modifiers of hemostasis.
Grzegorski SJ, Liu Y, Richter CE, Yaman M, Vo AH, Yu X, Dahlgren AR, Madarati H, Friedmann AP, Surakka I, Kim PY, Kretz CA, Shavit JA. 2026 May 13; DOI:10.64898/2026.05.11.724445
PMID: 42182511