Sonya J Wolf-Fortune, PhD

 Sonya J. Wolf-Fortune
Assistant Professor of Pharmacology
Assistant Professor of Microbiology and Immunology
Office:
University of Michigan Medical School
Pharmacology
1150 W Medical Center Dr, MSRBIII 1301B
Ann Arbor, Michigan 48103
Email:
[email protected]
Phone:
Available to mentor
Sonya J Wolf-Fortune, PhD
Sonya J. Wolf-Fortune
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications

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    • Qualifications
    • Postdoctoral Fellow
      University of Michigan Medical School, Ann Arbor, United States
      2024
    • PhD
      University of Michigan Medical School, Ann Arbor, United States
      2019
    • BS
      Prairie View A&M University, Prairie View, United States
      2013

    Center Memberships
    • Center Member
      Caswell Diabetes Institute

    Research Overview

    The Wolf-Fortune lab aims understand the molecular mechanisms linking chronic skin inflammatory conditions, such as psoriasis, and metabolic dysfunction. We have a particular interest in studying epigenetic regulation and structural-immune cell crosstalk. This work will provide new mechanistic insights for novel therapeutic intervention for patients with chronic skin inflammatory conditions and type 2 diabetes.

    Links
    • Wolf-Fortune Lab

    Recent Publications

     See All Publications
    • Journal Article
      IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3
      Moon JY, Wolf SJ, Joshi AD, Zhang H, Shadiow J, Bauer TM, Mangum KD, Hughes LD, Audu CO, Melvin WJ, Barrett EC, Rocco S, de Jimenez GS, Estor AL, Nelapudi M, Li Q, Bogle R, Levi B, Davis FM, Obi AT, Moore BB, Tsoi LC, Gudjonsson JE, Gallagher KA. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-025-67456-3
      PMID: 41413388
    • Journal Article
      The histone methyltransferase SETDB2 modulates keratinocyte inflammatory phenotype in diabetic wound repair via an IFNβ/JAK/STAT mechanism 2142
      Moon JY, Wolf-Fortune S, Joshi A, Mangum KD, Bauer T, Shadiow J, Audu CO, Melvin WJ, Moore B, Davis F, Obi AT, Gallagher K. The Journal of Immunology, 2025 Nov 23; 214 (Supplement_1): DOI:10.1093/jimmun/vkaf283.104
    • Journal Article
      53-OR: Loss of HDAC11 Drives Aortic Endothelial-to-Mesenchymal Transitioning
      SHADIOW J, BAUER TM, MANGUM KD, JOSHI A, MOON J, SALDANA DE JIMENEZ G, ROCCO SA, HUGHES L, BUCKLEY S, WHITE JR MJ, OVALLE AM, REYES-ARBUJAS JJ, WOLF-FORTUNE S, GALLAGHER K. Diabetes, 2025 Jun 16; 74 (Supplement_1): DOI:10.2337/db25-53-or
    • Proceeding / Abstract / Poster
      416 Epigenetic regulation of keratinocyte-mediated IFN kappa expression in IMQ-induced psoriasis
      Wolf-Fortune S, Joshi A, Moon J, Mangum K, Bauer T, Shadiow J, Gudjonsson JE, Kahlenberg M, Gallagher K. Journal of Investigative Dermatology, 2024 Jul 20; 144 (8): s72 DOI:10.1016/j.jid.2024.06.432
    • Proceeding / Abstract / Poster
      The Histone Demethylase JMJD3 Regulates Smooth Muscle Cell Phenotype during Macrophage-mediated Inflammation
      Mangum KD, Bauer T, Joshi A, Wolf-Fortune S, Moon J, Li Q, Gudjonsson J, Obi A, Davis F, Gallagher K. Journal of Vascular Surgery, 2024 May 21; 79 (6): e292 DOI:10.1016/j.jvs.2024.03.376
    • Presentation
      Examining the chronic skin inflammation-diabetes axis
      Wolf-Fortune S. 2023 Oct 4;
    • Journal Article
      29-OR: Diabetic Wound Keratinocytes Induce Macrophage JMJD3–Mediated Nlrp3 Expression
      WOLF-FORTUNE S, MOON J, JOSHI A, MAZUMDER P, BARRETT E, MANGUM KD, GALLAGHER K. Diabetes, 2023 Jun 21; 72 (Supplement_1): DOI:10.2337/db23-29-or
    • Proceeding / Abstract / Poster
      458-P: Proinflammatory Macrophage Phenotype Modulates Vascular Smooth Muscle Cell Differentiation via the Histone Demethylase JMJD3
      MANGUM KD, JOSHI A, MAZUMDER P, WOLF-FORTUNE S, BARRETT E, MOORE B, DAVIS FM, GALLAGHER K. Diabetes, 2023 Jun 21; 72 (Supplement_1): DOI:10.2337/db23-458-p