Vishwaratn Asthana
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About
My professional interests center around providing generalized inpatient care in the hospital while identifying clinical research problems and developing bioengineering-inspired solutions in the lab: from bedside to bench. I enjoy working with diverse patient populations of all ages and backgrounds.
Qualifications
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Internal Medicine ResidencyUniversity of Michigan–Ann Arbor, Ann Arbor, United States
Residency
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T32 FellowMichigan Medicine, Ann Arbor, United States
2023
Residency
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MDBaylor College of Medicine, Houston, United States
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PhDRice University, Houston, United States
Center Memberships
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Center MemberWeil Institute for Critical Care Research
Research Overview
My current research expertise is in nucleic acid-based diagnostics and therapeutics. I am using this to develop a diagnostic device that is intended to identify the causative pathogen in sepsis in under an hour with the goal of improving patient outcomes and addressing emerging antibiotic resistance.
My research broadly focuses on creating nucleic acid-based diagnostics and therapeutics to address unmet clinical needs. Currently, my research entails developing a novel diagnostic device capable of identifying causative pathogens in sepsis in just a few hours, with the ultimate goal of improving patient outcomes and addressing emerging antibiotic resistance.
Recent Publications
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Asthana V, Martínez Nieves E, Bugga P, Smith C, Dunn T, Narayanasamy S, Dickson R, VanEpps JS. Journal of Infectious Diseases, 2024 Oct 30;Journal ArticleDevelopment of a rapid, culture-free, universal microbial identification system using internal transcribed spacer targeting primers
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Asthana V, Nieves EM, Bugga P, Smith C, Dunn T, Narayanasamy S, Dickson RP, VanEpps JS. J Infect Dis, 2024 Nov 6;Journal ArticleDevelopment of a rapid, culture-free, universal microbial identification system using internal transcribed spacer targeting primers.
DOI:10.1093/infdis/jiae545 PMID: 39503259 -
Wellman C, Smith C, Bugga P, Asthana V, VanEpps J. 2024 Jul 31;PatentMethod and Apparatus For Stacked Multi-Filter Device For Customized Fluid Sample Filtration And Extraction
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Asthana V, Bugga P, Smith CE, Wellman C, Dwight Z, Ranjan P, Nieves EM, Dickson R, VanEpps S. 2024 Oct 10; bioRxiv,PreprintGenomicGapID: Leveraging Spatial Distribution of Conserved Genomic Sites for Broad-Spectrum Microbial Identification
DOI:10.1101/2024.10.07.617038 -
Asthana V, Nieves EM, Bugga P, Smith C, Dunn T, Narayanasamy S, Dickson R, VanEpps S. 2024 Sep 21; bioRxiv,PreprintA rapid, inexpensive, culture-free, universal bacterial identification system using internal transcribed spacer targeting primers: a proof-of-principle study
DOI:10.1101/2024.09.15.613074 -
Perkins SJ, Monovoukas D, Chopra Z, Kucharski K, Powell C, Vejalla A, Latchamsetty R, Bugga P, Asthana V. Ann Noninvasive Electrocardiol, 2024 Sep; 29 (5): e70013Journal ArticleVectorcardiography Predicts Heart Failure in Patients Following ST Elevation Myocardial Infarction.
DOI:10.1111/anec.70013 PMID: PMC11424495 -
Bugga P, Asthana V, Drezek R. PLoS One, 2024 19 (8): e0305002Journal ArticleSimulation-guided tunable DNA probe design for mismatch tolerant hybridization.
DOI:10.1371/journal.pone.0305002 PMID: PMC11340886 -
VanEpps J, Bugga P, Asthana V, Martinez-Nieves E. 2024 Jul 29;PatentA Method to Remove Non-Target Nucleic Acids from Clinical and Non-Clinical Samples for Downstream Microbial Detection