Vallerie McLaughlin

profile-vallerie-mclaughlin-2023
Kim A Eagle M.D. Endowed Professor of Cardiovascular Medicine
Program Associate
Internal Medicine
Professor of Internal Medicine
Medical School
Michigan Medicine
Cardiovascular Medicine
1500 E. Medical Center Drive, SPC 5853
Ann Arbor, Michigan 48109-5853
[email protected]
Available to mentor
Vallerie McLaughlin
profile-vallerie-mclaughlin-2023
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • Manage Your Profile

  • Qualifications

    • MD
      Northwestern University Medical School, Evanston, IL, United States
      1985 - 1989
    • BS
      Northwestern University, Evanston, IL, United States
      1981 - 1985

    Center Memberships

    • Center Member
      Samuel and Jean Frankel Cardiovascular Center

    Research Overview

    1. Pulmonary Hypertension
    2. Pulmonary vascular disease

    Recent Publications

    See All Publications
    • Journal Article
      D28-20 ADVANCE Outcomes: A Phase 3, Randomized Clinical Trial Evaluating Ralinepag for Pulmonary Arterial Hypertension
      Mclaughlin VV, Ataya A, Barbera JA, Benza RL, Meyer GB, Chang S, Channick RN, Feenstra JF, Gaine SP, Giannakoulas G, Diaz CS, Khanna D, Kim NH, Lachant DJ, Oudiz RJ, Preston IR, Sood N, Torres F, Vachiery JE, Zamudio TP, Cella D, Escudero M, Lacasse V, Solum DT, Humbert MJ. American Journal of Respiratory and Critical Care Medicine, 2026 Jun 24; 212 (Supplement_2): aamag286.300 DOI:10.1093/ajrccm/aamag286.300
    • Journal Article
      Sotatercept Safety and Efficacy in Intermediate-Low Risk Pulmonary Arterial Hypertension: A Pooled Analysis of PULSAR and STELLAR.
      Gomberg-Maitland M, Ghofrani HA, Gibbs JSR, Hoeper MM, Humbert M, McLaughlin VV, Preston IR, Souza R, Waxman AB, Miller B, Lin J, Shi Y, Perchenet L, Strait J, Cornell AG, Badesch DB. Chest, 2026 May 27; DOI:10.1016/j.chest.2026.04.056
      PMID: 42208730
    • Journal Article
      Circulating Biomarker Results From a Phase 2 Study of Seralutinib in Pulmonary Arterial Hypertension.
      Osterhout R, Boucly A, Benza RL, Channick RN, Chin KM, Frantz RP, Hemnes AR, Howard LS, Mclaughlin VV, Sitbon O, Vachiéry J-L, Zamanian RT, Aranda R, Cravets M, Ding Z, Duong-Verlé T, Mottola D, Roscigno RF, Sitapara R, Zisman LS, Bruey J-M, Ghofrani H-A. Am J Respir Crit Care Med, 2026 May 8; DOI:10.1093/ajrccm/aamag175
      PMID: 42104009
    • Journal Article
      A19-03 Efficacy and Safety of Sotatercept in Patients With Pulmonary Arterial Hypertension (PAH) Associated With Connective Tissue Disease (CTD): A Pooled Analysis From STELLAR, ZENITH, and HYPERION
      Souza R, Badesch DB, Ghofrani HA, Gibbs S, Gomberg-Maitland M, Hoeper M, Humbert M, Preston IR, Waxman AB, Grünig E, Hassoun P, Highland KB, Mathai SC, Miller B, Lin J, Shi Y, Brambatti M, Loureiro M, Cornell AG, Mackenzie HS, Perchenet L, Dezia A, Mclaughlin VV. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5479 DOI:10.1093/ajrccm/aamag162.5479
    • Journal Article
      A19-05 Efficacy and Safety of Sotatercept in Patients With Pulmonary Arterial Hypertension Receiving Double-background Therapy: A Pooled Analysis From PULSAR, STELLAR, ZENITH, and HYPERION
      Mclaughlin VV, Badesch DB, Ghofrani HA, Gibbs S, Gomberg-Maitland M, Hoeper M, Preston IR, Souza R, Waxman AB, Grünig E, Kopéc G, Olsson KM, Shi Y, Miller B, Lin J, Martinez EC, Brambatti M, Humbert M. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5481 DOI:10.1093/ajrccm/aamag162.5481
    • Journal Article
      A65-09 UNISUS Hemodynamic Sub-study: Study Design and Patient Characteristics from the First Head-to-head Superiority Study in Pulmonary Arterial Hypertension (PAH)
      Humbert MJ, Backer A, Boyanova N, Hoeper MM, Kracker H, Lack G, Mclaughlin VV, Preston I, Tamura Y. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5571 DOI:10.1093/ajrccm/aamag162.5571
    • Journal Article
      B106-05 Efficacy and Safety of Sotatercept in Patients With Pulmonary Arterial Hypertension (PAH) Classified as Intermediate-low Risk: A Pooled Analysis From PULSAR, STELLAR, and HYPERION
      Gomberg-Maitland M, Ghofrani HA, Gibbs S, Hoeper M, Humbert M, Mclaughlin VV, Preston IR, Souza R, Waxman AB, Miller B, Liu C, Shi Y, Perchenet L, Cornell AG, Badesch DB. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5736 DOI:10.1093/ajrccm/aamag162.5736
    • Journal Article
      C64-14 Pharmacokinetic/Pharmacodynamic (PK/PD) Sub-study of UNISUS in Pulmonary Arterial Hypertension (PAH): Characteristics of Enrolled Patients
      Preston IR, Boyanova N, Csonka D, Humbert M, Kracker H, Mclaughlin VV, Tamura Y, Hoeper MM. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5831 DOI:10.1093/ajrccm/aamag162.5831

    Featured News & Stories

    heart graphic navy and yellow
    Health Lab

    Biologic drug reduces symptoms, hospitalization for severe pulmonary hypertension after diagnosis

    Prescribing the biologic drug sotatercept alongside standard treatment for the most severe form of pulmonary hypertension significantly reduces the likelihood of worsening disease when added within the first year after diagnosis, according to a study published in the New England Journal of Medicine by Michigan Medicine.