Nicolaas Bohnen, MD

 Nicolaas Bohnen
Professor of Radiology
Professor of Neurology
Medical School
Office:
University of Michigan Medical School
Radiology
24 Frank Lloyd Wright Dr., Lobby B, Rm 100
Ann Arbor, Michigan 48105
Email:
[email protected]
Phone:
Available to mentor
Nicolaas Bohnen, MD
Nicolaas Bohnen
Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • About

    Dr. Bohnen is professor of Radiology and Neurology at the University of Michigan. He attended medical school in the Netherlands and completed a PhD in neuropsychology. He completed residency training in neurology (Mayo Clinic, Rochester, MN) and nuclear medicine (University of Michigan, Ann Arbor, MI). He was a fellow in movement disorders at the University of Michigan Medical Center. He holds clinical appointments in the Departments of Radiology (Division of Nuclear Medicine), Neurology at the University of Michigan, and the Ann Arbor VA (movement and cognitive disorders clinic). Dr. Bohnen’s research interests include the use of PET and MRI in the study of neurodegenerative disorders and normal aging. He is the director of the UM Functional Neuroimaging, Cognitive and Mobility Laboratory where his clinical research has a focus on neurobiological correlates of cognition, vestibular and multisensory processing during gait and postural control, olfaction and mobility in normal aging and in Parkinson disease.

    Links
    • Functional Neuroimaging, Cognitive and Mobility Laboratory (FNICOMO Lab)

    Qualifications
    • Residency
      University of Michigan Health, Nuclear Medicine, United States
      1996 - 1998
      Residency
    • Residency
      Mayo Clinic, Neurology, United States
      1992 - 1996
      Residency
    • Epidemiology
      Mayo Clinic, Rochester, United States
      1991 - 1992
      Postdoctoral Fellowship
    • PhD
      University of Limburg, Maastricht, Maastricht, Netherlands
      1987 - 1991
    • MD
      Rabdoud University Nijmegen Medical Centre, Nijmegen, Netherlands
      1979 - 1987

    Center Memberships
    • Center Member
      Frankel Institute for Heart and Brain Health

    Research Overview

    The Functional Neuroimaging, Cognitive, and Mobility (FNiCoMo) Laboratory is part of the Departments of Radiology and Neurology at the University of Michigan. The mission of this lab is to gain a better understanding of how the architecture of the brain and functional processes in the brain (obtained with functional neuroimaging) determine cognitive functioning and mobility both in patients with neurodegenerative diseases (such as Parkinson's Disease) and in normal aging.

    Recent Publications

     See All Publications
    • Journal Article
      Pathology and Genetics in a Global Cohort of Parkinsonian Disorders.
      Wu LY, du Toit T, Georgiades T, Stafford EJ, Levine K, Fang Z-H, Jasaityte S, Martinez A-LG, Cullinane P, De Pablo-Fernandez E, Blauwendraat C, Singleton AB, Scholz SW, Traynor BJ, Wood N, Hardy J, Chinnery P, Houlden H, Cain R, Troakes C, Chelban V, Serrano GE, Gveric D, McLean C, Love S, King A, Robinson AC, Roncaroli F, Shepherd C, Halliday G, Parkkinen L, Morris CM, Smith C, Beach TG, Gentleman S, Warner TT, Lashley T, Jaunmuktane Z, Real R, Morris HR, Global Parkinson’s Genetic Program (GP2) . JAMA Neurol, 2026 Aug 1; 83 (8): 798 - 807. DOI:10.1001/jamaneurol.2026.1634
      PMID: PMC13247843
    • Journal Article
      A Bayesian network analysis of gait speed change upon transition to uneven surfaces in older adults
      Song Y, Rosano C, Chahine LM, Rosso AL, Ambrosio F, Bohnen N, Chen Z, Kim S. Journals of Gerontology Series A Biological Sciences and Medical Sciences, 2026 Jul 1; 81 (7): DOI:10.1093/gerona/glag137
      PMID: 42184285
    • Journal Article
      Topography of Regional Cerebral GABAA Receptor Availability in Parkinson's Disease Patients With Freezing of Gait
      Hart AA, Kanel P, Barr J, Carli G, Vangel R, Michalakis F, Scott PJH, Roytman S, Bohnen NI. European Journal of Neuroscience, 2026 Jul 1; 64 (1): DOI:10.1111/ejn.70618
      PMID: 42400317
    • Preprint
      Effect of levodopa treatment on gait in older adults with mild parkinsonian signs
      Pongmala C, Roytman S, van Emde Boas M, Vangel R, Rosano C, Bohnen N. 2026 Jun 8; medRxiv, DOI:10.64898/2026.06.04.26354926
    • Presentation
      Parkinson's disease
      Bohnen N. 2026 Sep 17;
    • Presentation
      Whole brain 11C-PE2I dopamine transporter PET imaging in persons with Parkinson's with freezing of gait or fall
      Bohnen N. 2026 Sep 17;
    • Journal Article
      Cholinergic system changes in levodopa-unresponsive freezing of gait and failure of goal-directed motor behavior in Parkinson's disease.
      Bohnen NI, Roytman S, Carli G, Chou KL, Kanel P, Albin RL. Neural Regen Res, 2026 Jun 8; DOI:10.4103/NRR.NRR-D-25-01957
    • Journal Article
      White matter lesions disrupt cholinergic pathways important for cognition in Parkinson's disease.
      Carli G, Brown T, Michalakis F, Biddix A, Roytman S, Vangel R, Van Hout A, Kanel P, Scott P, Albin RL, Bohnen NI. Brain, 2026 May 12; DOI:10.1093/brain/awag172
      PMID: 42117428