Pratyusha Yalamanchi, MD, MBA

 Pratyusha Yalamanchi
Clinical Assistant Professor
Available to mentor
Pratyusha Yalamanchi, MD, MBA
Pratyusha Yalamanchi
Clinical Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Recent Publications

  • Manage Your Profile

    • About

    Dr. Yalamanchi is an Assistant Professor of Head and Neck Oncology and Microvascular Reconstruction in the Department of Otolaryngology Head and Neck Surgery. Her clinical practice includes all aspects of head and neck surgical oncology and reconstructive surgery with particular interest in management of head and neck parapharyngeal masses/carotid body tumors, endocrine surgery, transoral robotic surgery, and microvascular reconstruction of head and neck defects after oncologic resection.

    She brings her clinical perspective to her role as a Faculty Expert at the Institute of Healthcare Policy and Innovation at the University of Michigan, with a focus on value-based oncologic care delivery. She has an MBA in Healthcare Management with specific training in quantitative analysis, particularly in cost-based analyses, and operations experience.

    Qualifications
    • Postdoctoral Fellow in Head and Neck, Cranial Base and Microvascular Reconstructive Surgery
      Vanderbilt University Medical Center, Department of Otolaryngology - Head and Neck Surgery, Nashville, TN, United States
      2023 - 2024
      Postdoctoral Fellowship
    • Resident
      University of Michigan, Department of Otolaryngology - Head and Neck Surgery, Ann Arbor, MI, United States
      2018 - 2023
      Residency
    • Administrative Chief Resident
      University of Michigan, Department of Otolaryngology - Head and Neck Surgery, Ann Arbor, MI, United States
      2022 - 2023
      Chief Resident
    • MD with Distinction
      University of Pennsylvania - Perelman School of Medicine, Philadelphia, PA, United States
      2013 - 2018
    • MBA, Healthcare Management
      University of Pennsylvania - Wharton School, Philadelphia, PA, United States
      2016 - 2018
    • BA with High Honors, Human Evolutionary Biology
      Harvard University, Cambridge, MA, United States
      2009 - 2013

    Center Memberships
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      Rogel Cancer Center

    Recent Publications

     See All Publications
    • Journal Article
      Costs and system-wide considerations within head and neck reconstruction: moving toward a value-based care framework
      Mead M, Yalamanchi P. Current Opinion in Otolaryngology and Head and Neck Surgery, 2026 Oct 1; 34 (5): 349 - 355. DOI:10.1097/MOO.0000000000001142
      PMID: 42329698
    • Journal Article
      Rural-Urban disparities in head and neck cancer mortality in the United States: Subsite-Specific Trends, 2010–2024
      Thomas EA, Liu J, Yu M, Heft Neal ME, Yalamanchi P, Buchakjian MR, Forner DWA. Oral Oncology, 2026 Oct 1; 181: DOI:10.1016/j.oraloncology.2026.108111
      PMID: 42585754
    • Journal Article
      Combined Positive Score and Cost-Effectiveness of Perioperative Pembrolizumab for Head and Neck Cancer. Epub ahead of print
      Coyle AH, Hutton DW, Buchakjian MR, Casper KA, Forner DW, Hawley ST, Heft Neal ME, Malloy KM, Mierzwa ML, Prince ME, Shah JL, Sweicicki PL, Shuman AG, Stucken CL, Veenstra CM, Worden FP, Yalamanchi P. JAMA Otolaryngology Head and Neck Surgery, 2026 Sep 1; e262124 - e262124. DOI:10.1001/jamaoto.2026.2124
    • Journal Article
      Robotic tongue base surgery for obstructive sleep apnea
      Lenze NR, Nathan J, Yalamanchi P, Hoff PT. Operative Techniques in Otolaryngology Head and Neck Surgery, 2026 Jun 1; 37 (2): 135 - 139. DOI:10.1016/j.otot.2026.05.005
    • Chapter
      Robotic tongue base surgery for obstructive sleep apnea
      Lenze N, Nathan J, Yalamanchi P, Hoff P. 2026 Jul 2; 37: Operative Techniques in Otolaryngology-Head and Neck Surgery, 135 - 139. DOI:10.1016/j.otot.2026.05.005
    • Journal Article
      Accuracy and Safety of Patient-Facing GenAI Platforms in Post-Laryngectomy Care
      Casper J, Prince A, Knill C, Lyden T, Hardenbergh A, Ambrose M, Mierzwa ML, Buchakjian M, Dave F, Prince ME, Heft-Neal ME, Yalamanchi P. International Journal of Radiation Oncology • Biology • Physics, 2026 Apr 18; 125 (1): e40 - e41. DOI:10.1016/j.ijrobp.2026.02.080
    • Journal Article
      Validation of MyHPVscore: a high-performance HPV ctDNA lab developed test
      Mierzwa M, Brenner C. Journal of Molecular Diagnostics, 2026 Apr 30;
    • Journal Article
      Late Recurrences Beyond Five Years in Salivary Adenoid Cystic Carcinoma: Implications for Long-Term Surveillance
      Dalal PJ, Dermody SM, Ali H, Brummel C, Chad Brenner J, Buchakjian M, Casper KA, Chinn SB, Forner D, Hasan D, Malloy KM, McHugh J, Mierzwa M, Heft Neal ME, Prince ME, Shah J, Shuman AG, Stucken CL, Spector ME, Yalamanchi P, Worden FP, Swiecicki PL. Oto Open, 2026 Apr 1; 10 (2): DOI:10.1002/oto2.70259

    Featured News & Stories

         cancer cell floating with yellow dots drawn out blue
    Health Lab

    Biomarkers aid cost-benefit analysis of head and neck cancer immunotherapy

    The cost-effectiveness of the immunotherapy drug pembrolizumab for patients with locally advanced head and neck squamous cell carcinoma may depend on biomarker results, according to a new study by Michigan Medicine.