Max S Wicha, MD
Madeline and Sidney Forbes Professor of Oncology and Professor of Internal Medicine
Medical School
[email protected]
Available to mentor
Max S Wicha, MD
Professor
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Qualifications
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Biology DegreeState University of NY at Stony Brook, United States
1966 - 1970
Center Memberships
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Center MemberRogel Cancer Center
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Center MemberTaubman Institute
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberMM-PKUHSC Joint Institute
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Center MemberBiointerfaces Institute
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberGlobal REACH
Research Overview
Mammary cell biology
* Regulation of mammary growth, differentiation and apoptosis
* Stem cells in normal mammary development and breast cancer
* Cancer stem cell therapeutics
Recent Publications
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Koksalar Alkan F, Caglayan AB, Alkan HK, Lee E, Piranlioglu R, Jones C, Alimadadi M, Brown E, Arnold A, Langer Gramer A, Vogl T, Dyson G, Chadli A, Kasimir-Bauer S, Assad H, Boerner J, Al Achkar M, Azmi AS, Neamati N, Ozturk G, Bollag R, Hedrick CC, Korkaya H, Wicha M, Shi H. 2026 Jun 14; bioRxiv,PreprintS100A9-Dependent CXCR2hi Neutrophils Mediate Systemic Immune Suppression and Checkpoint Resistance in Metastatic TNBC
DOI:10.64898/2026.06.09.731132 -
Celiker N, Alkan FK, Alkan HK, Caglayan A, Lawal A, Al Achkar M, Max WS, Korkaya H. Cancer Research, 2026 Apr 5; 86 (7_Supplement): 184 - 184.Journal ArticleAbstract 184: TNF-alpha plays pleiotropic role in innate immune activation and blood-brain barrier disruption driving brain metastasis.
DOI:10.1158/1538-7445.am2026-184 -
Lawal AM, Alkan FK, Alkan HK, Caglayan AB, Celiker N, Temby B, WICHA M, Al Achkar M, Purrington K, Korkaya H. Cancer Research, 2026 Apr 5; 86 (7_Supplement): 2375 - 2375.Journal ArticleAbstract 2375: Stress-responsive immune microenvironment in triple-negative breast cancer among African American women
DOI:10.1158/1538-7445.am2026-2375 -
Alkan F, Alkan HK, Caglayan A, Caglayan A, Lawal A, Celiker N, Shi H, Vogl T, Neamati N, Max W, Korkaya H. Cancer Research, 2026 Apr 5; 86 (7_Supplement): 3431 - 3431.Journal ArticleAbstract 3431: Neutrophil-like monocytes (NeuMos) with high levels of CXCL2 expression orchestrate systemic granulopoiesis and drive immunotherapy resistance in TNBC
DOI:10.1158/1538-7445.am2026-3431 -
Caglayan AB, Xin Y, Caglayan A, Nagaraja S, Sharma D, Hager C, Koksalar-Alkan F, Alkan HK, Burness M, Korkaya H, Wicha MS. Cancer Research, 2026 Apr 5; 86 (7_Supplement): 6110 - 6110.Journal ArticleAbstract 6110: Systemic inflammation induced by calprotectin (S100A8/S100A9 complex) triggers reactivation of dormant cells in mouse models of breast cancer
DOI:10.1158/1538-7445.am2026-6110 -
Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee H-J, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P. Nat Immunol, 2026 Mar 24;Journal ArticleAuthor Correction: Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
DOI:10.1038/s41590-026-02504-8 PMID: 41876720 -
Zhao N, Zhao P, Tapaswi A, Polemi K, Thong T, Sexton J, Charles S, Wicha MS, Svoboda L, Zhou X, Colacino JA. 2026 Feb 26; bioRxiv,PreprintExploring the Influence of Chemical Exposures in Breast Cancer Disparities: High-Throughput Transcriptomic Analysis in Normal Breast Cells from Diverse Donors
DOI:10.64898/2026.02.23.707203 -
2026 Feb 4;PresentationMetabolic and immunologic targeting of breast cancer stem cells
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