Ling Qi
Adjunct Professor of Molecular and Integrative Physiology
Adjunct Professor of Internal Medicine
[email protected]
Available to mentor
Ling Qi
Adjunct Professor
Manage Your Profile
Center Memberships
-
Center MemberCaswell Diabetes Institute
Recent Publications
-
Lin LL, Maldosevic E, Zhou LE, Jomaa A, Qi L. Nature Communications, 2026 Dec 1; 17 (1):Journal ArticleStructural basis and pathological implications of the dimeric OS9-SEL1L-HRD1 ERAD Core Complex
DOI:10.1038/s41467-026-68777-7 PMID: 41593065 -
Zhao L, He Z, Sun Y, Sun M, Liu Z, Zhou Z, Qi L, Luo Y, Ji Y, Liang T. Nature Communications, 2026 Dec 1; 17 (1):Journal ArticleUbiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling
DOI:10.1038/s41467-025-67219-0 PMID: 41372171 -
Maldosevic E, Gora RJ, Lin LL, Zhou LE, Li ZJ, Peskova Y, Qi L, Shan S-O, Jomaa A. Nat Commun, 2026 Mar 27;Journal ArticleA molecular switch in NAC prevents mitochondrial protein mistargeting by SRP.
DOI:10.1038/s41467-026-71061-3 PMID: 41896572 -
Chen X, Wang S, Torres M, Hao S, Sun S, Qi L. Proc Natl Acad Sci U S A, 2026 Mar 24; 123 (12): e2529914123Journal ArticleSEL1L-HRD1 ERAD-autophagy interplay maintains mitochondrial homeostasis in brown adipocytes.
DOI:10.1073/pnas.2529914123 PMID: 41843682 -
Wang HH, Wang Z, Lin LL, Verma SK, Gniadzik W, Wang H, Li ZJ, Whitestone E, Jiang L, Kuyumcu-Martinez MN, Sun S, Qi L. EMBO J, 2026 Mar 20;Journal ArticleFunctional rescue of a disease-linked ERAD pathway mutation via alternative splicing.
DOI:10.1038/s44318-026-00757-5 PMID: 41862645 -
Zhu W, Pan L, Cui X, Russo AC, Ray R, Pederson B, Wei X, Lin LL, Torres M, Hafner H, Gregg B, Shrestha N, Liu C, Naji A, Arvan P, Sandoval DA, Lindberg I, Qi L, Reinert RB. Nat Commun, 2026 Feb 25;Journal ArticleSEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet α cells.
DOI:10.1038/s41467-026-69928-6 PMID: 41741474 -
Torres M, Lu Y, Pederson B, Wang H, Gretzinger A, Lin L, Hwang J, Chen X, Rupp AC, Tomlinson AJ, Scott AJ, Zhao Z, Wahl DR, Myers M, Lyssiotis CA, Qi L. J Clin Invest, 2026 Feb 19;Journal ArticleNeuronal SEL1L-HRD1 ER-associated degradation is essential for motor function and survival in mice.
DOI:10.1172/JCI196819 PMID: 41712288 -
Zhang X, Lin LL, Pan L, Wei X, Wang HH, Li ZJ, Qi L. Proceedings of the National Academy of Sciences of the United States of America, 2026 Feb 10; 123 (6):Journal ArticleFunctional integrity of the SEL1L–HRD1 complex is critical for endoplasmic reticulum–associated degradation and organismal viability
DOI:10.1073/pnas.2517927123 PMID: 41642983
