Daniel A Lawrence
Frederick G L Huetwell Legacy Professor of Basic Research in Cardiovascular Medicine
Professor of Internal Medicine
Professor of Molecular and Integrative Physiology, Medical School
Email:
[email protected]
Available to mentor
Daniel A Lawrence
Professor
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Center Memberships
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberWeil Institute for Critical Care Research
Recent Publications
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Pettey AC, Ito S, Franklin MK, Howatt DA, Moorleghen JJ, Levitan BM, Graf DB, Guzmán VZ, Zhang N, Lawrence DA, Sisson TH, Sawada H, Saffitz JE, Lu HS, Daugherty A. Cardiovasc Res, 2026 Oct 28;Journal ArticleCardiac hemorrhage precedes hypertension-induced fibrosis in plasminogen activator inhibitor-1 deficient mice.
DOI:10.1093/cvr/cvag260 PMID: 42946663 -
Wang J, Su EJ, Lawrence DA, Eitzman DT. Scientific Reports, 2026 Oct 9;Journal ArticleEmpagliflozin attenuates traumatic brain injury-induced atherosclerosis and norepinephrine-induced vascular smooth muscle cell responses
DOI:10.1038/s41598-026-73123-4 -
Shaydakov ME, Emal CD, Rainey JP, Lawrence DA, Diaz JA. Phlebology, 2026 Sep 1; 41 (8): 735 - 738.Journal ArticlePAI-1 Inhibition in experimental venous thrombosis
DOI:10.1177/02683555261421027 PMID: 41568932 -
Gan Y, Liang W, Liu C, Yalavarthi S, Warnock M, Sabb K, Sarosh C, Schaefer JK, Tambralli A, Madison JA, Emal CD, Tsou PS, Shi H, Zuo Y, Lawrence DA, Knight JS. Journal of Autoimmunity, 2026 Jun 1; 161:Journal ArticleEndothelial cell-derived plasminogen activator inhibitor-1 potentiates thrombosis in antiphospholipid syndrome
DOI:10.1016/j.jaut.2026.103563 PMID: 42048835 -
Ngodup T, Elson B, Mello AM, Hannifin S, Liu M, Zhang Y, Shi J, Shah YM, Lawrence DA, di Magliano MP, Lee KE. Science Advances, 2026 Apr 3; 12 (14):Journal ArticleA stromal PAI1-tPA axis orchestrates immunosuppression in pancreatic cancer
DOI:10.1126/sciadv.aea6734 PMID: 41931610 -
Zhai T, Zhang W, Ma C, Ni L, Paulus YM, Su EJ, Murphy GG, Lawrence DA, Wang X. Photoacoustics, 2026 Apr 1; 48:Journal ArticleMulti-parametric longitudinal imaging of cerebral biomarkers in a rodent model of Alzheimer's disease
DOI:10.1016/j.pacs.2026.100808 -
Su EJ, Tsou PS, Warnock M, Subbotina N, Mann K, Vichaikul S, Rosek A, Leung L, Xing X, Xing E, Plazyo O, Bogle R, Tsoi LC, Emal CD, Khanna D, Varga J, Sisson TH, Gudjonsson JE, Lawrence DA. Jci Insight, 2026 Feb 17; 11 (7):Journal ArticleA potent inhibitor of PAI-1, MDI-2517, mitigates disease severity in a preclinical systemic sclerosis model
DOI:10.1172/jci.insight.195005 PMID: 41701900 -
Zuchelkowski BE, Inman KW, Nouraie SM, Beru N, Naqvi A, Qin S, Yeh CH, Zhang Y, Shah FA, Sharma L, Cruz CSD, Zhang L, McVerry BJ, MD AM, Neal MD, Seheult J, Kitsios GD, Mellors JW, Lawrence DA, Kim PY, Jacobs JL, Bain WG. Journal of the American Heart Association, 2026 Jan 1; 15 (10): 1 - 13.Journal ArticleSoluble Thrombomodulin Links Viremia and Mortality During COVID-19: Results From the ACTIV-4a Trial
DOI:10.1161/JAHA.125.047693 PMID: 42089155
