David A Williams, PhD

portrait of David A. Williams
Professor of Anesthesiology
Professor of Internal Medicine
Professor of Psychiatry
Program Associate, Chronic Pain and Fatigue Research Center, Medical School
Professor of Psychology, College of Literature, Science, and the Arts
Available to mentor
David A Williams, PhD
portrait of David A. Williams
Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Dr. Williams is a Professor of Anesthesiology, Medicine (Rheumatology), Psychiatry, and Psychology at the University of Michigan where he also serves as the Associate Director of the Chronic Pain and Fatigue Research Center. He received his doctorate from the Ohio State University and has previously held faculty appointments at both Duke and at Georgetown University Medical Centers. He is both a clinician and researcher with publications in the areas of chronic illness management, digital health, patient-reported outcomes instrument development and validation, and mechanisms of pain perception/modulation. In 2019, he became the University of Michigan site PI for PCORnet where he can facilitate the conduct of multi-site clinical research. Nationally and internationally, he serves on numerous scientific editorial boards and scientific review committees including his recent service to the Interagency Pain Research Coordinating Committee (IPRCC).

    Links

    • MICHR/NBRU
    • HEAL K12

    Qualifications

    • Fellow
      Duke University School of Medicine, Durham, United States
      1988 - 1990
      Clinical Fellowship
    • Inetern
      Duke University School of Medicine, Durham, United States
      1987 - 1988
      Internship
    • Ph.D., Clinical Psychology
      Ohio State University, Columbus, OH, United States
      1984 - 1988

    Center Memberships

    • Center Member
      Institute for Healthcare Policy and Innovation

    Research Overview

    Dr. Williams has been publishing pain-related research since 1984 including studies in basic science, human experimental methods, clinical studies and clinical trials, mechanisms of pain processing and modulation, and psychometric instrument development and validation. He has worked for many years to develop and refine cognitive and behavioral pain self-management interventions both in face-to-face formats and digital formats. PainGuide.com is a public-facing product of this ongoing work which is also embedded in the clinical trials being conducted by the NIH HEAL initiative consortium BACPAC. Patient-reported outcomes (PROs) represent another area of his specialization. For many years he worked with the NIH PROMIS initiative to develop IRT and brief CAT-based measures of multiple health-related domains. More recently his work has focused on assessing Chronic Overlapping Pain Conditions (COPCs) and includes the COPC-screener. His work with PCORnet includes helping to develop and maintain the UM infrastructure for participating in national-scale multi-site clinical research – including participation in the NIH RECOVER initiative focused on COVID and Long Haul COVID (PASC). Mentoring in clinical research is another one of his passions. He is a mentor in many in training programs both within UM and at other institutions. Directing and shaping new educational programs in clinical pain research, such as the HEAL National K12 (co-PI) is an example hihs work in this field.

    Recent Publications

    See All Publications
    • Additional Scholarship
      Chronic Overlapping Pain Conditions Screener - The REDCap Version: Users Guide, Version 11.0
      Williams DA, Schrepf A, Maixner W. 2023 Feb 21;
    • Additional Scholarship
      "PainGuide - Self-management resources for chronic pain."
      Williams DA. 2020
    • Journal Article
      The MAPP research network: design, patient characterization and operations.
      Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ, MAPP Research Network Study Group . BMC Urol, 2014 Aug 1; 14: 58 DOI:10.1186/1471-2490-14-58
      PMID: PMC4126395
    • Preprint
      Generalized Sensory Sensitivity for Prediction of Post-Surgical Analgesic Outcomes: An Observational Cohort Study of Total Hip Arthroplasty and Hysterectomy.
      Schrepf A, Smith T, Waller N, Harris RE, Ichesco E, Kaplan CM, Till SR, Williams DA, As-Sanie S, Evanski JM, Urquhart A, Brummett CM, Clauw DJ, Harte SE. 2026 May 27; DOI:10.64898/2026.05.26.26354108
      PMID: 42245048
    • Journal Article
      Self-reported Measures of Nociplastic Pain are Associated with Reduced Response to Endoscopic Retrograde Cholangiopancreatography in Chronic Pancreatitis.
      Machicado JD, Guevara-Lazo D, Bay M, Harte SE, Williams DA, Clauw DJ. Pancreas, 2026 May 18; DOI:10.1097/MPA.0000000000002681
      PMID: 42153736
    • Journal Article
      1005 Improving Sleep Quality as a Mechanism for Alleviating Pain Severity: Evidence from a Three-Arm RCT of Psychological Treatments for Fibromyalgia
      Jennings M, Kalmbach D, Williams D, Lumley M. Sleep, 2026 May 10; 49 (Supplement_1): a447 - a448. DOI:10.1093/sleep/zsag091.1004
    • Proceeding / Abstract / Poster
      1025 Associations of Subjective and Objective Sleep Quality with Pain and Depression Among Adults with Fibromyalgia
      Gonzalez-Prado R, Lumley M, Jennings M, Harte S, Williams D. Sleep, 2026 May 10; 49 (Supplement_1): a456 - a457. DOI:10.1093/sleep/zsag091.1024
    • Journal Article
      Exploring Gamification of the Incentive Spirometry Tracker Device: A Survey of Patients, Providers, and Healthcare Employees.
      Alrubaie N, Chen T, Hoffmann A, Ernst A, Varghese J, Wu Z, Rozek SB, Williams DA, Wong A, Campbell D, Inchauste TM, Kheterpal S, Sinha A, Mentz G, Shah N, Burns ML. Anesthesiology, 2026 Apr 17; DOI:10.1097/ALN.0000000000006102
      PMID: 41996546

    Featured News & Stories

    Research By the Numbers FY22.jpg
    Department News

    U-M Anesthesiology ranked #1 in NIH funding for eighth consecutive year with more than $22M in funding

    Three researchers — Drs. George Mashour, Chad Brummett, and David Williams — ranked in top 7 for PI funding.