David A Williams, PhD
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About
Dr. Williams is a Professor of Anesthesiology, Medicine (Rheumatology), Psychiatry, and Psychology at the University of Michigan where he also serves as the Associate Director of the Chronic Pain and Fatigue Research Center. He received his doctorate from the Ohio State University and has previously held faculty appointments at both Duke and at Georgetown University Medical Centers. He is both a clinician and researcher with publications in the areas of chronic illness management, digital health, patient-reported outcomes instrument development and validation, and mechanisms of pain perception/modulation. In 2019, he became the University of Michigan site PI for PCORnet where he can facilitate the conduct of multi-site clinical research. Nationally and internationally, he serves on numerous scientific editorial boards and scientific review committees including his recent service to the Interagency Pain Research Coordinating Committee (IPRCC).
Links
MICHR/NBRU HEAL K12
Qualifications
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FellowDuke University School of Medicine, Durham, United States
1988 - 1990
Clinical Fellowship
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IneternDuke University School of Medicine, Durham, United States
1987 - 1988
Internship
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Ph.D., Clinical PsychologyOhio State University, Columbus, OH, United States
1984 - 1988
Center Memberships
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Center MemberInstitute for Healthcare Policy and Innovation
Research Overview
Dr. Williams has been publishing pain-related research since 1984 including studies in basic science, human experimental methods, clinical studies and clinical trials, mechanisms of pain processing and modulation, and psychometric instrument development and validation. He has worked for many years to develop and refine cognitive and behavioral pain self-management interventions both in face-to-face formats and digital formats. PainGuide.com is a public-facing product of this ongoing work which is also embedded in the clinical trials being conducted by the NIH HEAL initiative consortium BACPAC. Patient-reported outcomes (PROs) represent another area of his specialization. For many years he worked with the NIH PROMIS initiative to develop IRT and brief CAT-based measures of multiple health-related domains. More recently his work has focused on assessing Chronic Overlapping Pain Conditions (COPCs) and includes the COPC-screener. His work with PCORnet includes helping to develop and maintain the UM infrastructure for participating in national-scale multi-site clinical research – including participation in the NIH RECOVER initiative focused on COVID and Long Haul COVID (PASC). Mentoring in clinical research is another one of his passions. He is a mentor in many in training programs both within UM and at other institutions. Directing and shaping new educational programs in clinical pain research, such as the HEAL National K12 (co-PI) is an example hihs work in this field.
Recent Publications
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Williams DA, Schrepf A, Maixner W. 2023 Feb 21;Additional ScholarshipChronic Overlapping Pain Conditions Screener - The REDCap Version: Users Guide, Version 11.0
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Williams DA. 2020Additional Scholarship"PainGuide - Self-management resources for chronic pain."
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Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ, MAPP Research Network Study Group . BMC Urol, 2014 Aug 1; 14: 58Journal ArticleThe MAPP research network: design, patient characterization and operations.
DOI:10.1186/1471-2490-14-58 PMID: PMC4126395 -
Schrepf A, Smith T, Waller N, Harris RE, Ichesco E, Kaplan CM, Till SR, Williams DA, As-Sanie S, Evanski JM, Urquhart A, Brummett CM, Clauw DJ, Harte SE. 2026 May 27;PreprintGeneralized Sensory Sensitivity for Prediction of Post-Surgical Analgesic Outcomes: An Observational Cohort Study of Total Hip Arthroplasty and Hysterectomy.
DOI:10.64898/2026.05.26.26354108 PMID: 42245048 -
Machicado JD, Guevara-Lazo D, Bay M, Harte SE, Williams DA, Clauw DJ. Pancreas, 2026 May 18;Journal ArticleSelf-reported Measures of Nociplastic Pain are Associated with Reduced Response to Endoscopic Retrograde Cholangiopancreatography in Chronic Pancreatitis.
DOI:10.1097/MPA.0000000000002681 PMID: 42153736 -
Jennings M, Kalmbach D, Williams D, Lumley M. Sleep, 2026 May 10; 49 (Supplement_1): a447 - a448.Journal Article1005 Improving Sleep Quality as a Mechanism for Alleviating Pain Severity: Evidence from a Three-Arm RCT of Psychological Treatments for Fibromyalgia
DOI:10.1093/sleep/zsag091.1004 -
Gonzalez-Prado R, Lumley M, Jennings M, Harte S, Williams D. Sleep, 2026 May 10; 49 (Supplement_1): a456 - a457.Proceeding / Abstract / Poster1025 Associations of Subjective and Objective Sleep Quality with Pain and Depression Among Adults with Fibromyalgia
DOI:10.1093/sleep/zsag091.1024 -
Alrubaie N, Chen T, Hoffmann A, Ernst A, Varghese J, Wu Z, Rozek SB, Williams DA, Wong A, Campbell D, Inchauste TM, Kheterpal S, Sinha A, Mentz G, Shah N, Burns ML. Anesthesiology, 2026 Apr 17;Journal ArticleExploring Gamification of the Incentive Spirometry Tracker Device: A Survey of Patients, Providers, and Healthcare Employees.
DOI:10.1097/ALN.0000000000006102 PMID: 41996546
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