Corentin Cras-Meneur

 Corentin Cras Meneur
Associate Research Scientist
Internal Medicine
Medical School
University of Michigan Medical School
Internal Medicine (MEND Division)
2800 Plymouth Rd, B20-213W
Ann Arbor, MI 48109
[email protected]
Available to mentor
Corentin Cras-Meneur
Corentin Cras Meneur
Associate Research Scientist
  • About
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  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • About

    Dr. Cras-Méneur studied pancreatic organogenesis for his Ph.D. under the supervision of Pr. Scharfmann in Hôpital Robert Debré (Paris, France). He received his Ph.D. in the “Molecular Genetics of Developmental Diseases and Oncogenesis” track at Université Paris 5 (René Descartes) in 2002.
    He then moved on for a postdoctoral fellowship on the functional genomics of the pancreas with Pr. M. Alan Permutt in Washington University School of Medicine in St. Louis, MO.
    In 2009, Dr. Cras-Méneur moved to the University of Michigan joining the faculty of Internal Medicine (Metabolism and Endocrinology Division).
    He is now the technical director of both the Rodent and Human Islet Cores of the University of Michigan.

    Links
    • Lab
    • Islet Core
    • linkedin
    • Researchgate
    • Google Scholar

    Qualifications
    • Postdoctoral fellowship
      Washington University in St. Louis School of Medicine, Internal Medicine (Division of Endocrinology, Metabolism & Lipid Research), St Louis, United States
      2002 - 2009
      Postdoctoral Fellowship
    • Ph.D.
      Paris Descartes University, Paris, France
      1998 - 2002

    Center Memberships
    • Center Member
      Caswell Diabetes Institute

    Research Overview

    Dr. Cras-Méneur’s work focuses on the events that regulate pancreatic β-cell differentiation and function. His work has been focused on three related axes:
    • Pancreatic development (mesenchyme-epithelium interactions, control of the fate of the endocrine cells).
    • Functional Genomics (bioinformatics analysis of the transcriptome of the endocrine pancreas under physiological and experimental conditions).
    • Insulin signaling (control of insulin biosynthesis, control of the proliferation and resistance to stress of the β-cells).

    Recent Publications

     See All Publications
    • Proceeding / Abstract / Poster
      A mini pancreas to investigate IPS vs isolated human islets in diabetes
      Yeganeh M, Lo J, Cras-Meneur C, Millman J, Chun T-H. 2025 Oct 8;
    • Proceeding / Abstract / Poster
      Novel imaging platform highlights the disconnect between β-cell mass and glucose control in the onset of type 1 diabetes
      Cras-Meneur C, Arvan P, Seeley R. 2023 Jun 23;
    • Proceeding / Abstract / Poster
      Generation of Patient-Specific Pancreatic Cells and 3D Islet Clusters for Diabetes Research and Novel Therapy Development
      Mundada L, Cras-Meneur C, Walker E, Soleimanpour S, Herron T. 2023 May 17;
    • Proceeding / Abstract / Poster
      Novel Imaging Platform Highlights the Disconnect Between β-Cell Mass and Glucose Control in the Onset of Type 1 Diabetes
      Cras-Meneur C, Arvan P, Seeley R. 2023 May 17;
    • Journal Article
      mTORC1 Regulates High Levels of Protein Synthesis in Retinal Ganglion Cells of Adult Mice.
      Fort PE, Losiewicz MK, Elghazi L, Kong D, Cras-Méneur C, Fingar DC, Kimball SR, Rajala RVS, Smith AJ, Ali RR, Abcouwer SF, Gardner TW. Journal of Biological Chemistry (in press), 2022 Jun 27; DOI:https://doi.org/10.1016/j.jb:
    • Journal Article
      mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice.
      Fort PE, Losiewicz MK, Elghazi L, Kong D, Cras-Méneur C, Fingar DC, Kimball SR, Rajala RVS, Smith AJ, Ali RR, Abcouwer SF, Gardner TW. The Journal of biological chemistry, 2022 Aug 6; 298 (6):
    • Journal Article
      Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance.
      Skovsø S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, Li H, Modi H, Wildi JS, Botezelli JD, Noh HL, Suk S, Gablaski B, Bautista A, Kim R, Cras-Méneur C, Flibotte S, Sinha S, Luciani DS, Nislow C, Rideout EJ, Cytrynbaum EN, Kim JK, Bernal-Mizrachi E, Alonso LC, MacDonald PE, Johnson JD. Nature communications, 2022 Aug 6; 13 (1):
    • Journal Article
      Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose
      Frikke-Schmidt H, Arvan P, Seeley RJ, Cras-Méneur C. Scientific Reports, 2025 Apr 30; 11 (1): DOI:10.1038/s41598-020-79727-8