Jon-Fredrik Nielsen, PhD

 Jon-Fredrik Nielsen, PhD
Research Associate Professor, Functional MRI Laboratory
Research Associate Professor, Biomedical Engineering, Medical School
Email:
[email protected]
Available to mentor
Jon-Fredrik Nielsen, PhD
Jon-Fredrik Nielsen, PhD
Research Associate Professor
  • About
  • Qualifications
  • Research Overview
  • Recent Publications

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    • About

    I am an MRI physicist in the functional MRI laboratory (now part of UM Radiology), specializing in developing, implementing, and disseminating new MRI pulse sequences. I collaborate with researchers in UM Neurology, Radiology, and Engineering, to improve functional and structural MRI. My works mostly involves brain imaging, but the techniques I have helped develop can also be used in other contexts.

    Qualifications
    • PhD
      Ohio State University, Columbus, United States
      1995 - 2001
    • BS
      University of Georgia, Athens, United States
      1992 - 1995

    Research Overview

    My main areas of research and development are: (1) making MRI measurements more robust across sites and scanner vendor platforms, (2) designing 'shaped' radiofrequency (RF) pulses that select a 2D/3D region to be imaged (as opposed to conventional 1D slice-selective RF pulses), and (3) quantitative MRI with a focus on brain tissue characterization in, e.g., neurodegenerative disease.

    Recent Publications

     See All Publications
    • Preprint
      Vendor-Agnostic Joint Relaxometry and Myelin Water Fraction Mapping with B1 and Motion Correction
      Gallastegi UD, Fujita S, Jun Y, Delattre-Klauser A, Piredda GF, Hilbert T, Ariyurek C, Milshteyn E, Li S, Chen Y, Yong X, Chan K-S, Liu Q, Yee S, Rathi Y, Zaitsev M, Nielsen J-F, Afacan O, Jaimes C, Grant PE, Gagoski B, Bilgic B. 2026 Aug 12; arXiv,
    • Preprint
      Phantom- and simulation-based validation of combined diffusion relaxometry in ex vivo ADRD white matter.
      Jacobson A, Murguia A, Swanson SD, Nielsen J-F, Fessler JA, Seraji-Bozorgzad N. 2026 Apr 30; DOI:10.64898/2026.04.27.721146
      PMID: 42094567
    • Preprint
      OpenMRF: A Modular, Vendor-Neutral Open-Source Framework for Reproducible Magnetic Resonance Fingerprinting using Pulseq
      Griesler T, Stebani J, Kaplan S, Angelov I, Albert P, Blaimer M, Wech T, Wang X, Chen Q, Zaitsev M, Zhu Z, Liu Q, Martin P, Nielsen J-F, Hamilton JI, Nordbeck P, Seiberlich N, Gram M. 2026 Apr 28; arXiv, DOI:10.48550/arxiv.2604.22713
    • Preprint
      OpenMRF: A Modular, Vendor-Neutral Open-Source Framework for Reproducible Magnetic Resonance Fingerprinting using Pulseq.
      Griesler T, Stebani J, Kaplan S, Angelov I, Albert P, Blaimer M, Wech T, Wang X, Chen Q, Zaitsev M, Zhu Z, Liu Q, Martin P, Nielsen J-F, Hamilton JI, Nordbeck P, Seiberlich N, Gram M. 2026 Apr 24;
      PMID: 42078496
    • Journal Article
      A vendor-neutral functional MRI acquisition protocol for multi-site studies.
      Nielsen J-F, Egan MK, Chen Q, Shafiekhani M, Wang JH, Hurley SA, Soldate JS, Lisinksi J, LaConte SM, Sutton BP, Waggoner RA, Stirnberg R, Stöcker T, Fessler JA, Noll DC, Zaitsev M, Peltier SJ. Apert Neuro, 2026 6 (SI 1): DOI:10.52294/001c.155279
      PMID: PMC13268408
    • Journal Article
      Comment: naming convention for gradient system transfer function and gradient system frequency response for magnetic resonance imaging encoding field characterization
      Wehkamp N, Hucker P, Fischer J, Greiner A, Nielsen JF, Zaitsev M, Dehnert R. Magnetic Resonance Materials in Physics Biology and Medicine, 2026 Jan 1; DOI:10.1007/s10334-025-01314-7
    • Journal Article
      Correction: Comment: naming convention for gradient system transfer function and gradient system frequency response for magnetic resonance imaging encoding field characterization (Magnetic Resonance Materials in Physics, Biology and Medicine, (2026), 10.1007/s10334-025-01314-7)
      Wehkamp N, Hucker P, Fischer J, Greiner A, Nielsen JF, Zaitsev M, Dehnert R. Magnetic Resonance Materials in Physics Biology and Medicine, 2026 Jan 1; DOI:10.1007/s10334-026-01336-9
    • Journal Article
      Improved Accuracy of Multidimensional Spatially-Selective Saturation RF Pulses for Short-Repetition-Time Steady-State Imaging
      He Y, Noll DC, Nielsen JF. Magnetic Resonance in Medicine, 2026 Jan 1; DOI:10.1002/mrm.70573
      PMID: 42649576