Joseph Holoshitz
Professor of Internal Medicine
Medical School
[email protected]
Available to mentor
Joseph Holoshitz
Professor
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Recent Publications
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Carver JJ, Pugh BA, Ma Q, Caillier SJ, Denbrock RR, Martines CC, Puckett AE, Roberson TC, Fernandez-Viña MA, Hollenbach JA, Oksenberg J, Holoshitz J, Didonna A. Neurology R Neuroimmunology Neuroinflammation, 2026 May 1; 13 (3): e200580Journal ArticleShared Epitope-Positive HLA Alleles Protect Against Alpha-Synuclein Pathology in a Model of Parkinson Disease
DOI:10.1212/NXI.0000000000200580 PMID: 41996655 -
Miglioranza Scavuzzi B, van Drongelen V, Kaur B, Fox JC, Liu J, Mesquita-Ferrari RA, Kahlenberg JM, Farkash EA, Benavides F, Miller FW, Sawalha AH, Holoshitz J. Commun Biol, 2022 Jul 28; 5 (1): 751Journal ArticleThe lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope.
DOI:10.1038/s42003-022-03717-x PMID: PMC9334592 -
Miglioranza Scavuzzi B, Holoshitz J. Antioxidants (Basel), 2022 Jun 29; 11 (7):Journal ArticleEndoplasmic Reticulum Stress, Oxidative Stress, and Rheumatic Diseases.
DOI:10.3390/antiox11071306 PMID: PMC9312221 -
van Drongelen V, Miglioranza Scavuzzi B, Holoshitz J. Rheumatology (Oxford), 2022 Mar 2; 61 (3): 889 - 891.Journal ArticleThe Cusp theory: is there more to HLA-disease association?
DOI:10.1093/rheumatology/keab624 PMID: 34436565 -
Scavuzzi BM, van Drongelen V, Holoshitz J. Front Immunol, 2022 13: 814967Journal ArticleHLA-G and the MHC Cusp Theory.
DOI:10.3389/fimmu.2022.814967 PMID: PMC8913506 -
van Drongelen V, Scavuzzi BM, Nogueira SV, Miller FW, Sawalha AH, Holoshitz J. Sci Rep, 2021 Jan 28; 11 (1): 2599Journal ArticleHLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization.
DOI:10.1038/s41598-021-82195-3 PMID: PMC7844024 -
Kim J, Chun K, McGowan J, Zhang Y, Czernik PJ, Mell B, Joe B, Chattopadhyay S, Holoshitz J, Chakravarti R. Proc Natl Acad Sci U S A, 2021 Aug 24; 118 (34):Journal Article14-3-3ζ: A suppressor of inflammatory arthritis.
DOI:10.1073/pnas.2025257118 PMID: PMC8403930 -
van Drongelen V, Ali WH, Holoshitz J. J Immunol, 2020 Aug 1; 205 (3): 579 - 586.Journal ArticleUncovering a Shared Epitope-Activated Protein Citrullination Pathway.
DOI:10.4049/jimmunol.1901108 PMID: PMC7372319
