Paul W Harms

 Paul W. Harms
Clinical Professor of Pathology
Clinical Professor of Dermatology
Medical School
[email protected]
Available to mentor
Paul W Harms
Paul W. Harms
Clinical Professor
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  • Research Overview
  • Recent Publications

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    • About

    Dr. Paul Harms is a board-certified pathologist and dermatopathologist.

    Center Memberships
    • Center Member
      Rogel Cancer Center

    Research Overview

    Dr. Harms has interested in molecular markers and mechanisms of cutaneous diseases, especially cutaneous neoplasia. His work has advanced understanding of the genomic drivers of multiple skin malignancies, especially Merkel cell carcinoma.

    Recent Publications

     See All Publications
    • Journal Article
      Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis
      Jiang R, Kirma J, Fox J, Xing X, Wang J, Sarkar MK, Bogle R, Do T, Coon A, Cole C, Plazyo O, Rew JE, Zhang H, Kahlenberg JM, Billi AC, Bachelez H, Tsoi LC, Harms PW, Shao S, Chen X, Gudjonsson JE. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-025-67917-9
      PMID: 41436466
    • Preprint
      An immunocompetent Merkel cell carcinoma model for preclinical studies
      Verhaegen ME, Bhatia S, Singer KL, Baumbick M, Huang P-W, Syu L-J, Wilbert D, Selig A, Farjo GA, Walter E, Wolinski N, Furgal A, Galloway D, Harms PW, Cieslik M, Dlugosz AA. 2026 Jun 28; bioRxiv, DOI:10.64898/2026.06.25.734228
    • Preprint
      Multiomic Analysis Reveals an IFN-driven Cellular Landscape Effectively Targeted by Ruxolitinib in Hailey-Hailey Disease.
      Ceccacci S, Minh Pham HD, Dessaignes M, Mirzayan J, Roger K, Tsoi LC, Harms PW, Gudjonsson JE, Puig Lombardi ME, Guerrera IC, Hovnanian A. 2026 Jun 4; DOI:10.64898/2026.06.01.729262
      PMID: 42282850
    • Journal Article
      CARMN fusions and PDGFRB mutations highlight key differences amongst cutaneous tumors with myopericytic differentiation.
      Del Castillo Velasco-Herrera M, Cheema S, Wong K, Billington J, Vermes I, Anderson E, Ferla E, Harms PW, de Saint Aubain N, Clarke EL, Merchant W, Alomari AK, Rajan N, Ferguson P, Weigelt MA, Monteagudo C, Billings SD, Arends MJ, Ferreira I, Brenn T, van der Weyden L, Adams DJ. J Invest Dermatol, 2026 May 14; DOI:10.1016/j.jid.2026.04.036
      PMID: 42140550
    • Journal Article
      Single-cell and spatial profiling reveal cDC2A-CXCL13+CD8+ T-epithelial cell crosstalk and cytotoxicity through TNFRSF9 in cutaneous and mucosal lichen planus.
      Jiang R, Bogle R, Xing X, Kirma J, Fox J, Harms PW, Do T, Billi AC, Kahlenberg JM, Modlin RL, Teles R, West J, Mangold A, Zhang H, Schneider MA, Bruno S, Roediger B, Martiny-Baron G, Tsoi LC, Hacini-Rachinel F, Röhn TA, Gudjonsson JE. Nat Commun, 2026 Mar 14; DOI:10.1038/s41467-026-70506-z
      PMID: 41832141
    • Journal Article
      406 Adverse Outcome in Merkel Cell Carcinoma with Microsatellitosis - A Clinicopathologic Study Of 25 Cases
      Wiedemeyer K, Harms P, Bresler S. Laboratory Investigation, 2026 Mar 24; 106 (3): 104689 DOI:10.1016/j.labinv.2025.104689
    • Journal Article
      Cellular neurothekeoma is driven by copy number deletions, providing potential diagnostic and therapeutic avenues
      Sousa-Squiavinato ACM, Billington J, Del Castillo Velasco-Herrera M, Wong K, Cheema S, Vermes I, Anderson E, Vasisht A, Harms PW, Clarke EL, Merchant W, Weigelt MA, Billings SD, Monteagudo C, Alomari AK, Arends MJ, Wiedemeyer K, Ferreira I, Brenn T, van der Weyden L, Adams DJ. British Journal of Dermatology, 2026 Mar 1; 194 (3): 593 - 595. DOI:10.1093/bjd/ljaf487
      PMID: 41365817
    • Journal Article
      RB1 inactivation in cutaneous carcinomas
      Liv T, Touzé A, Schrama D, Guyétant S, Samimi M, Tetzlaff MT, Wood BA, Harms PW, Kervarrec T. Histopathology, 2026 Mar 1; 88 (4): 769 - 789. DOI:10.1111/his.70056
      PMID: 41395640