MeiLan K Han MD, MS
Pulmonary & Critical Care Medicine
1150 West Medical Center Drive, 6220C MSRB III
Ann Arbor, MI 48109
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About
MeiLan Han, MD MS, is a Professor of Medicine and Chief of the Division of Pulmonary and Critical Care at the University of Michigan Health. Dr. Han received her medical degree from the University of Washington in Seattle, WA. She completed her residency in Internal Medicine and fellowship in Pulmonary and Critical Care Medicine at the University of Michigan. Dr. Han has also completed a Master's Degree program in Biostatistics and Clinical Study Design at the University of Michigan School of Public Health.
Dr. Han’s research has focused on defining phenotypes in COPD using imaging. She is a lead investigator for several NIH sponsored COPD studies. She also serves as a spokesperson for the American Lung Association and on the board for the COPD Foundation. She is currently a Deputy Editor for the American Journal of Respiratory and Critical Care Medicine and serves as a member of the Global Obstructive Lung Disease scientific committee which is charged with developing internationally an internationally recognized consensus statement on COPD diagnosis and management. She is also the author of a book on lung health for the lay public, Breathing Lessons.
Links
http://drmeilanhan.com/ Breathing Lessons twitter linkedin instagram facebook
Center Memberships
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Center MemberAI and Digital Health Innovation
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Center MemberWeil Institute for Critical Care Research
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Center MemberTaubman Institute
Research Overview
Dr. Han’s research focuses on understanding patient heterogeneity to define disease subtypes in chronic obstructive pulmonary disease (COPD). In particular, Dr. Han has expertise in thoracic CT imaging with a particular focus on better understanding early disease and diversity in the pathways towards disease progression. Working with colleagues at the University of Michigan, Dr. Han has helped to validate the application of a dynamic image registration technique (Parametric Response Mapping) to thoracic CT scans in COPD. She is the University of Michigan Principal Investigator for both the SPIROMICS and COPDGene studies which are NIH funded cohort studies in COPD.
Recent Publications
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Wang JM, Pugashetti JV, Thompson J, Kang E, Kazerooni EA, Flaherty KR, Belloli EA, Sheth JS, O'Dwyer DN, Han MK, Hatt CR, Oldham JM, Chung JH. Chest, 2026 Aug 12;Journal ArticleSurvival According to Radiomic and Visual UIP Classification in Fibrotic ILD.
DOI:10.1016/j.chest.2026.08.002 PMID: PMC13494922 -
Bush A, Chotirmall SH, Han MK, Harhay M. Am J Respir Crit Care Med, 2026 Jul 28;Journal ArticleTo the Airway and Beyond: Introduction to an AJRCCM Special Section on Airway Disease.
DOI:10.1093/ajrccm/aamag368 PMID: 42518197 -
Bafadhel M, Martinez FJ, Criner GJ, Tashkin DP, Wechsler ME, Han MK, Singh D. Chest, 2026 Jul 25;Journal ArticleUsing Historical Blood Eosinophil Counts to Guide Treatment Decisions in Patients With Chronic Obstructive Pulmonary Disease.
DOI:10.1016/j.chest.2026.06.060 PMID: 42501940 -
Singh D, Stacey R, Halpin DMG, Bhatt SP, Crawford J, Drury T, Di Boscio V, Kolterer S, Han MK. Am J Respir Crit Care Med, 2026 Jun 11;Journal ArticleDefining disease stability in COPD: Evidence from Phase 3 clinical trials.
DOI:10.1093/ajrccm/aamag292 PMID: 42281286 -
Criner GJ, Watz H, Han MK, Martinez FJ, Gould S, Min J, Biswas A, Kolterer S, Singh D. Am J Respir Crit Care Med, 2026 Jun 9;Journal ArticleMepolizumab Efficacy in COPD: Insights from Longitudinal Patterns of Blood Eosinophil Counts and Their Variability Across Three Clinical Trials.
DOI:10.1093/ajrccm/aamag288 PMID: 42265988 -
Fortis S, Gerard SE, Strand M, Motahari A, Bhatt SP, Han MK, Crapo JD, Silverman EK, Reinhardt JM, Hoffman EA, Comellas AP. Ann Am Thorac Soc, 2026 Jun 8;Journal ArticleAssociation of "Emptying Emphysema" with Clinical and Radiographic Features in People with Smoking History.
DOI:10.1093/annalsats/aaoag151 PMID: 42261268 -
Bosma CB, Xu L, Murray S, Paulin LM, Kaufman JD, Hansel NN, Alexis NE, Barr RG, Bon J, Bose S, Comellas AP, Cooper CB, Couper D, Curtis JL, Galban CJ, Hatt CR, Hermann EA, Hoffman EA, Kazerooni EA, Kizhakke Puliyakote AS, Martinez FJ, Ohar JA, Paine R, Putcha N, Raju S, Reinhardt JM, Sack C, Labaki WW, Han MK. Ann Am Thorac Soc, 2026 Jun 2;Journal ArticleAssociation Between Chronic PM2.5 Exposure and CT-Detected Lung Abnormalities in the SPIROMICS Cohort.
DOI:10.1093/annalsats/aaoag143 PMID: 42226013 -
Han MK, Stacey R, Halpin DMG, Bhatt SP, Crawford J, Di Boscio V, Singh D. American Journal of Respiratory and Critical Care Medicine, 2026 Jun 24; 212 (Supplement_2): aamag286.113Journal ArticleA16-10 Defining Disease Stability in COPD: A Post-Hoc Analysis of the Phase III IMPACT Trial
DOI:10.1093/ajrccm/aamag286.113
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