Thomas H SIsson, MD

 Thomas sisson
Clinical Professor of Internal Medicine
Medical Student Clerkship Director
Interim Director, Physician Scientist Training Program and Fellows, Internal Medicine, Medical School
Email:
[email protected]
Available to mentor
Thomas H SIsson, MD
Thomas sisson
Clinical Professor
  • Recent Publications

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    • Recent Publications

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    • Journal Article
      A potent inhibitor of PAI-1, MDI-2517, mitigates disease severity in a preclinical systemic sclerosis model
      Su EJ, Tsou PS, Warnock M, Subbotina N, Mann K, Vichaikul S, Rosek A, Leung L, Xing X, Xing E, Plazyo O, Bogle R, Tsoi LC, Emal CD, Khanna D, Varga J, Sisson TH, Gudjonsson JE, Lawrence DA. Jci Insight, 2026 Feb 17; 11 (7): DOI:10.1172/jci.insight.195005
      PMID: 41701900
    • Journal Article
      Degradation of oxidized phospholipids by lysosomal phospholipase A2 regulates pulmonary fibrosis
      Kwak D, Sisson T, Ling S, Shayman J, Subbotina N, Kim K. American Journal of Physiology - Lung Cellular and Molecular Physiology, 2025 Mar 24; 329 (2): L214 - L223.
    • Journal Article
      PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis
      Sisson T, Osterholzer J, leung L, Basrur V, Nesvizhskii A, subbotina N, warnock M, torrente D, virk A, Horowitz J, migliorini M, strickland D, Kim K, Huang S, Lawrence D. Journal of Clinical Investigation Insight, 2025 Jan 8; 10 (11): e186131 - e186131.
    • Journal Article
      SORL1 is a receptor for tau that promotes tau seeding
      Cooper JM, Lathuiliere A, Su EJ, Song Y, Torrente D, Jo Y, Weinrich N, Sales JD, Migliorini M, Sisson TH, Lawrence DA, Hyman BT, Strickland DK. Journal of Biological Chemistry, 2024 Jun 1; 300 (6): DOI:10.1016/j.jbc.2024.107313
      PMID: 38657864
    • Journal Article
      CD36/Lyn kinase interactions within macrophages promotes pulmonary fibrosis in response to oxidized phospholipid
      Kwak D, Bradley PB, Subbotina N, Ling S, Teitz-Tennenbaum S, Osterholzer JJ, Sisson TH, Kim KK. Respiratory Research, 2023 Dec 1; 24 (1): DOI:10.1186/s12931-023-02629-6
      PMID: 38098035
    • Presentation
      "Sustained Club Cell Injury Induces Histopathologic Features of Deployment-Related Constrictive Bronchiolitis"
      2022 Feb 1;
    • Journal Article
      Defibrotide therapy for SARS-CoV2 Acute Respiratory Distress Syndrome (ARDS).
      Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Chest, 2022 Aug 6;
    • Proceeding / Abstract / Poster
      Defibrotide therapy for SARS-CoV2 Acute Respiratory Distress Syndrome (ARDS).
      Frame D, Scappaticci GB, Braun TM, Maliarik M, Sisson TH, Pipe SW, Lawrence DA, Richardson PG, Holinstat M, Hyzy RC, Kaul DR, Gregg KS, Lama VN, Yanik GA. Chest, 2022 Aug 6;