ANNA VACHAPARAMPIL MATHEW, MBBS

MATHEW_Anna.jpg
Clinical Associate Professor of Internal Medicine
Medical School
University of Michigan Medical School
Internal Medicine - Nephrology
1000 Wall Street, 6116 Brehm
Ann Arbor, MI 48105
[email protected]
Available to mentor
ANNA VACHAPARAMPIL MATHEW, MBBS
MATHEW_Anna.jpg
Clinical Associate Professor
  • About
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  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    I am a Med-Peds trained Nephrologist conducting translational research using metabolomics, proteomics, and lipidomics.

    Links

    • Mathew Lab website
    • twitter
    • twitter

    Qualifications

    • Clinical Fellowship in Nephrology and Pediatric Nephrology
      University of California San Diego Medical Center, San Diego, United States
      2007 - 2011
      Postdoctoral Fellowship
    • Residency in Internal Medicine and Pediatrics
      University of Illinois at Chicago, Internal Medicine and Pediatrics, Chicago, United States
      2003 - 2007
      Residency
    • MBBS
      Chinglepet Medical College, Chengalpattu, Tamil Nadu, 603001, India
      1994 - 1998

    Center Memberships

    • Center Member
      Taubman Institute
    • Center Member
      Caswell Diabetes Institute

    Research Overview

    Metabolic basis of diabetic complications using our expertise in measuring static and flux levels of central carbon metabolites, amino acids, acylcarnitines, nucleotides, short-chain fatty acids, and bile acids using mass spectrometry.

    Recent Publications

    See All Publications
    • Journal Article
      WCN26-5001 ACYLCARNITINES IN PLASMA AND URINE ASSOCIATED WITH REMISSION OF PROTEINURIA IN FSGS/MCD: UNTARGETED METABOLOMIC ANALYSES FROM THE NEPTUNE COHORT
      Ozeki T, Alakwaa F, Mathew A, Drexler Y, Kretzler M, Mariani L. Kidney International Reports, 2026 Mar 26; 11 (4): 104473 DOI:10.1016/j.ekir.2026.104473
    • Journal Article
      Author Correction: Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
      Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee H-J, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P. Nat Immunol, 2026 Mar 24; DOI:10.1038/s41590-026-02504-8
      PMID: 41876720
    • Journal Article
      Plasma and Urine Acylcarnitines as Potential Biomarkers for Remission of Proteinuria in FSGS/Minimal Change Disease: Untargeted Metabolomics Study from the NEPTUNE Cohort
      Ozeki T, Alakwaa F, Mathew AV, Drexler Y, Kretzler M, Mariani LH. Journal of the American Society of Nephrology, 2025 Oct 24; 36 (10S): 10.1681/asn.2025rrr4b3kj DOI:10.1681/asn.2025rrr4b3kj
    • Journal Article
      High density lipoprotein particle size and function associate with new cardiovascular events in patients with chronic kidney disease
      Mathew AV, Han Y, Konje VC, Guo Y, Byun J, George A, Meza J, Rajagopalan S, Chen EE, Gillespie B, Saran R, Pennathur S. PLoS ONE, 2025 Apr 1; 20 (4 April): DOI:10.1371/journal.pone.0320803
    • Journal Article
      Lipidomics Analysis Reveals Biomarkers for Proteinuria Remission and Disease Progression in FSGS/Minimal Change Disease (MCD) from the NEPTUNE Cohort
      Ozeki T, Alakwaa F, Mathew AV, Kretzler M, Mariani LH. Journal of the American Society of Nephrology, 2024 Oct 30; 35 (10S): 10.1681/asn.2024nh8fh2hx DOI:10.1681/asn.2024nh8fh2hx
    • Proceeding / Abstract / Poster
      Determination of Plasma Free Amino Acids in Biological Samples using Liquid Chromatography-Tandem Mass Spectrometry
      Byun J, Pennathur S, Mathew A. 2024 Jun 6;
    • Proceeding / Abstract / Poster
      Determination of Plasma Free Amino Acids in Biological Samples using Liquid Chromatography-Tandem Mass Spectrometry
      Byun J, Pennathur S, Mathew A. 2024 Mar 5;
    • Journal Article
      Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease
      Mathew AV, Kayampilly P, Byun J, Nair V, Afshinnia F, Chai B, Brosius FC, Kretzler M, Pennathur S. American Journal of Physiology - Renal Physiology, 2024 Jan 1; 326 (1): F30 - F38. DOI:10.1152/ajprenal.00252.2022
      PMID: 37916286