Muneesh Tewari
Ray and Ruth Anderson-Laurence M Sprague Memorial Research Professor
Professor of Internal Medicine
Associate Division Chief, Basic Research
Professor of Biomedical Engineering
109 Zina Pitcher Place
Ann Arbor
MI, 48019
[email protected]

Available to mentor
Muneesh Tewari
Professor
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      Taubman Institute
    • Center Member
      Precision Health Initiative
    • Center Member
      Center for Computational Medicine and Bioinformatics
    Research Overview

    • CAR-T cell therapy and the role of NETosis and innate immunity in immune-based toxicities
    • Next generation cell-free nucleic acid liquid biopsy approaches for early detection and monitoring of cancer
    • Wearable sensors and machine learning for early disease detection and prediction using digital biomarkers; Bioinformatic and computational approaches for disease prediction
    • Microbiome modification and host effects in cellular and immunotherapies
    • Cancer Neuroscience (developing research area)

    Recent Publications See All Publications
    • Journal Article
      Data Preprocessing Techniques for AI and Machine Learning Readiness: Scoping Review of Wearable Sensor Data in Cancer Care.
      Ortiz BL, Gupta V, Kumar R, Jalin A, Cao X, Ziegenbein C, Singhal A, Tewari M, Choi SW. JMIR Mhealth Uhealth, 2024 Sep 27; 12: e59587 DOI:10.2196/59587
      PMID: 38626290
    • Journal Article
      Comparison of EV characterization by commercial high-sensitivity flow cytometers and a custom single-molecule flow cytometer.
      Kim J, Xu S, Jung S-R, Nguyen A, Cheng Y, Zhao M, Fujimoto BS, Nelson W, Schiro P, Franklin JL, Higginbotham JN, Coffey RJ, Shi M, Vojtech LN, Hladik F, Tewari M, Tigges J, Ghiran I, Jovanovic-Talisman T, Laurent LC, Das S, Gololobova O, Witwer KW, Xu T, Charest A, Jensen KVK, Raffai RL, Jones JC, Welsh JA, Nolan JP, Chiu DT. J Extracell Vesicles, 2024 Aug; 13 (8): e12498 DOI:10.1002/jev2.12498
      PMID: 39140467
    • Preprint
      Ultrasensitive amplification-free quantification of a methyl CpG-rich cancer biomarker by single-molecule kinetic fingerprinting.
      Dai L, Johnson-Buck A, Laird PW, Tewari M, Walter NG. 2024 Apr 10; DOI:10.1101/2024.04.06.587997
      PMID: 38645159
    • Journal Article
      CLIA Validation of a New High Performance HPV ct DNA Assay Covering Multiple High Risk HPV Types
      Hochfelder C, Walline H, Bhambhani C, Brummel C, Candford E, Akhdar R, Casper K, Chinn SB, Heft-Neal M, Malloy K, Shah JL, Shuman A, Spector M, Stucken CL, Worden F, Prince ME, Mierzwa M, Swiecicki P, Tewari M, Brenner C. International Journal of Radiation Oncology Biology Physics, 2024 Apr; 118 (5): 62 - 63.
    • Journal Article
      CLIA Validation of a New High Performance HPV ctDNA Assay Covering Multiple High Risk HPV Types
      Hochfelder C, Walline H, Bhambhani C, Brummel C, Sandford E, Akhdar R, Casper K, Chinn SB, Heft-Neal ME, Malloy K, Shah JL, Shuman A, Spector M, Stucken CL, Worden F, Prince ME, Mierzwa ML, Swiecicki PL, Tewari M, Brenner C. International Journal of Radiation Oncology • Biology • Physics, 2024 Apr; 118 (5): e62 - e63. DOI:10.1016/j.ijrobp.2024.01.139
    • Journal Article
      Longitudinal plasma proteomics in CAR T-cell therapy patients implicates neutrophils and NETosis in the genesis of CRS.
      Flora C, Olesnavich M, Zuo Y, Sandford E, Madhukar R, Rozwadowski M, Sugur K, Ly A, Canbaz AA, Shedeck A, Li G, Geer MJ, Yanik GA, Ghosh M, Frame DG, Bonifant CL, Jain T, Knight JS, Choi SW, Tewari M. Blood Adv, 2024 Mar 26; 8 (6): 1422 - 1426. DOI:10.1182/bloodadvances.2023010728
      PMID: 38266157
    • Journal Article
      Analysis of Complete Blood Count Data and Use in Classification Machine Learning Models to Predict Icans Incidence Following CAR-T Cell Therapy
      Olesnavich M, Sandford E, Ly A, Canbaz A, Rozwadowski M, Valle BO-D, Kumar R, Tang S, Bonifant CL, Jain T, Choi SW, Tewari M. Transplantation and Cellular Therapy, 2024 Feb; 30 (2): s133 - s134. DOI:10.1016/j.jtct.2024.01.027
    • Journal Article
      Distinguishing Infection- Vs. Non-Infection-Related Febrile Neutropenia in HCT Patients By Machine Learning Analysis of Continuous Body Temperature Data Collected Using a Wearable Sensor
      Ren X, Mayhew K, Rozwadowski M, Khan S, Rao A, Kumar R, Najarian K, Paludo J, Binder AF, Sung AD, Choi SW, Tewari M. Transplantation and Cellular Therapy, 2024 Feb; 30 (2): s119 - s120. DOI:10.1016/j.jtct.2024.01.006