Tom K Kerppola

 Tom K. Kerppola
Professor of Biological Chemistry, Medical School
Professor of Biophysics, College of Literature, Science, and the Arts
[email protected]
Available to mentor
Tom K Kerppola
Tom K. Kerppola
Professor
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    • About

    My laboratory investigates the mechanisms whereby transcription factor complexes regulate gene expression

    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      Caswell Diabetes Institute

    Recent Publications

     See All Publications
    • Journal Article
      Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFκB p50 recruitment
      Burns VE, Kerppola TK. Immunology, 2022 Sep 1; 167 (1): 105 - 121. DOI:10.1111/imm.13527
      PMID: 35751391
    • Journal Article
      Virus infection induces keap1 binding to cytokine genes, which recruits nf-κb p50 and g9a-glp and represses cytokine transcription
      Burns VE, Kerppola TK. Journal of Immunology, 2021 Sep 1; 207 (5): 1437 - 1447. DOI:10.4049/jimmunol.2100355
      PMID: 34400522
    • Journal Article
      ATR-101 inhibits cholesterol efflux and cortisol secretion by ATP-binding cassette transporters, causing cytotoxic cholesterol accumulation in adrenocortical carcinoma cells
      Burns VE, Kerppola TK. British Journal of Pharmacology, 2017 Jan 1; 174 (19): 3315 - 3332. DOI:10.1111/bph.13951
      PMID: 28710789
    • Journal Article
      Visualization of the Genomic Loci That Are Bound by Specific Multiprotein Complexes by Bimolecular Fluorescence Complementation Analysis on Drosophila Polytene Chromosomes
      Deng H, Kerppola TK. 2017 Jan 1; 589: 429 - 455. DOI:10.1016/bs.mie.2017.02.003
      PMID: 28336073
    • Journal Article
      ATR-101 disrupts mitochondrial functions in adrenocortical carcinoma cells and in vivo
      Cheng Y, Kerppola RE, Kerppola TK. Endocrine Related Cancer, 2016 Apr 1; 23 (4): 1 - 19. DOI:10.1530/ERC-15-0527
      PMID: 26843528
    • Journal Article
      KAP1 represses differentiation-inducible genes in embryonic stem cells through cooperative binding with PRC1 and derepresses pluripotency-associated genes
      Cheng B, Ren X, Kerppola TK. Molecular and Cellular Biology, 2014 Jan 1; 34 (11): 2075 - 2091. DOI:10.1128/MCB.01729-13
      PMID: 24687849
    • Journal Article
      Visualization of the Drosophila dKeap1-CncC interaction on chromatin illumines cooperative, xenobiotic-specific gene activation
      Deng H, Kerppola TK. Development Cambridge, 2014 Jan 1; 141 (16): 3277 - 3288. DOI:10.1242/dev.110528
      PMID: 25063457
    • Journal Article
      Regulation of Drosophila Metamorphosis by Xenobiotic Response Regulators
      Deng H, Kerppola TK. Plos Genetics, 2013 Feb 1; 9 (2): DOI:10.1371/journal.pgen.1003263
      PMID: 23408904