Carole Parent
Life Sciences Institute
210 Washtenaw Ave, Office 4437
Ann Arbor, MI 48109-2216
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About
Dr. Carole A. Parent obtained B.Pharm. and M.Sc. degrees from the Université of Montréal and a Ph.D. degree from the University of Illinois at Chicago. After completing a postdoctoral fellowship in the laboratory of Dr. Peter N. Devreotes in the Department of Biological Chemistry of the Johns Hopkins University School of Medicine Dr. Parent joined the Laboratory of Cellular and Molecular Biology at the NCI in 2000, received tenure in 2006, was appointed Deputy Chief in 2010, and Deputy Director of the Center for Cancer Research at the NCI in 2016. After 17 years at the NCI, Dr. Parent moved to the University of Michigan in 2017 as the inaugural Raymond and Lynne Ruddon Collegiate Professor in Cancer Biology and Pharmacology. She is jointly appointed in the Department of Cell & Developmental Biology. Her laboratory is housed in the Life Sciences Institute of the University of Michigan, where she is a Research Professor. Dr. Parent is a Fellow of the American Society for Cell Biology and of the American Association for the Advancement of Science.
Links
Parent Lab
Qualifications
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InstructorJohns Hopkins University School of Medicine, Baltimore, United States
1996 - 2000
Postdoctoral Research
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Postdoctoral FellowJohns Hopkins University School of Medicine, Biological Chemistry, Baltimore, United States
1992 - 1996
Postdoctoral Research
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PhDDepartment of Pharmacodynamics, College of Pharmacy University of Illinois at Chicago, Chicago, IL, United States
1988 - 1992
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MSDepartment of Pharmacology, Faculty of Medicine Université de Montréal, Montréal, Québec, Canada
1985 - 1987
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BSFaculty of Pharmacy Université de Montréal, Montréal, Québec, Canada
1981 - 1985
Center Memberships
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberRogel Cancer Center
Research Overview
Dr. Parent's research program focuses on identifying the mechanisms that mediate how neutrophils reach infection and injury as well as tumor sites. To do so, her group exploits complementary ex vivo and in vivo model systems, cutting-edge live imaging, and a transdisciplinary approach.
Recent Publications
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Parent C. 2026 Mar 12;PresentationNeutrophil Meeting 2026
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Parent C. 2026 Mar 12;PresentationNeutrophils, Inflammation and Resolution
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Parent C. 2026 Mar 12;PresentationLeukotriene B4 Signaling During Neutrophil Chemotaxis
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Parent C. 2026 Mar 12;PresentationPlenary Session Featured Speaker
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Cohen E, Xu Y, Ghodke S, Orosco A, Wang D, Johnson CN, Steen K, Sarkar MK, Özlü N, Tsoi LC, Gudjonsson JE, Marchal L, Hovnanian A, Parent CA, Coulombe PA. Sci Transl Med, 2026 Apr 8; 18 (844): eadx9123Journal ArticleKeratin 16 inhibits type I interferon responses in differentiating keratinocytes of stressed and diseased skin.
DOI:10.1126/scitranslmed.adx9123 PMID: 41950305 -
Singhal R, Zhang NW, Lee ZH, Bell HN, Dalal PJ, Solanki S, Huang W, Rebernick R, Sajjakulnukit P, Jasewicz H, Kumar R, Kotla NK, Huber A, Mallappa AV, Arya SB, Takahashi S, Kasano-Camones CI, Carpenter E, di Magliano MP, Moon JJ, Parent CA, Gonzalez FJ, Patterson AD, Green MD, Zou W, Stoffel EM, Lyssiotis CA, Shah YM. 2026 Apr 8; bioRxiv,PreprintFatty acids in the tumor microenvironment reprogram neutrophils to induce immunosuppression via adenosine
DOI:10.64898/2026.04.02.716169 -
Melis N, Chen D, Chen E, Madsen T, Ng Y, Subramanian B, Wang W, Parent C, Losert W, Weigert R. 2026 Mar 20; bioRxiv,PreprintSpatially Distinct Myosin II Architectures Regulate Protrusion Dynamics and Directional Persistence during Immune Cell Migration
DOI:10.64898/2026.03.13.711384 -
Parent C. 2026 Mar 13;PresentationAdvancements in Cancer Research Symposium
Featured News & Stories
New Publication from the Parent and Coulombe Labs
New Publication led by Dr. Subhash Arya (Parent Lab) in close collaboration with the Coulombe and Mosalaganti Labs!
New study reveals how shedding DNA allows pro-inflammatory immune cells to quiet inflammation