Sami J Barmada, MD, PhD
Angela Dobson Welch and Lyndon Welch Research Professor
Associate Professor of Neurology
Medical School
[email protected]
Available to mentor
Sami J Barmada, MD, PhD
Associate Professor
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Center Memberships
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Center MemberTaubman Institute
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberCaswell Diabetes Institute
Recent Publications
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Rana JK, Pinarbasi ES, Fernandez MG, Navratna V, Conway KS, Lieberman AP, Barmada SJ, Mosalaganti S. Acta Neuropathol, 2026 Jul 7; 152 (1):Journal ArticleCTE-type tau filaments in Alzheimer's disease with co-morbid LATE-NC.
DOI:10.1007/s00401-026-03052-z PMID: PMC13337903 -
Copley KE, Dykstra MM, Miller MR, Linsenmeier M, Lai L, Wang Y, Chang Y-W, Barmada SJ, Shorter J. Sci Adv, 2026 Jun 26; 12 (26): eady0256Journal ArticleIsoform-specific steric zippers drive aberrant assembly and mislocalization of shortened TDP-43.
DOI:10.1126/sciadv.ady0256 PMID: PMC13292936 -
Moore S, Julian DL, Alsop E, Gittings LM, Lorenzini I, McMillan M, Macklin-Isquierdo S, Lehmkuhl E, Kalab P, de Paula Moreira D, Hayes L, Donnelly C, Barmada SJ, Zarnescu DC, Van Keuren-Jensen K, Sattler R. bioRxiv, 2026 Jun 25;Journal ArticleADAR2-Mediated RNA Editing Promotes TDP-43 Nuclear Export and Alters RNA Binding.
DOI:10.64898/2026.06.22.730622 PMID: PMC13321060 -
Replogle JM, Marks JD, Fernandez MG, Yuan H, Yu D, Winters E, Jawahar VM, Deshmukh R, Sutanto R, Kowal I, Frankenfield A, Shi R, Carlomagno Y, Jansen-West K, Todd TW, Kopach A, Sandra Ndayambaje I, Qi YA, Shantaraman A, Pozo-Cabanell I, Sheth U, Yue M, Duong D, Ferguson SM, Bennett DA, Damme M, Boeve BF, Day GS, Kellman B, Skarnes WC, Petersen RC, Josephs KA, Graff-Radford NR, McDonough JA, Prudencio M, Barmada SJ, Zhang Y, Hao L, DeTure M, Rawlinson B, Engelberg-Cook E, Casey MC, Perez N, Dickson DW, Wingo A, Liu Y, Seyfried NT, Wingo TS, Mosalaganti S, Petrucelli L, Ward ME. 2026 Mar 28;PreprintNeurodegeneration risk variants promote lysosomal TMEM106B fibril accumulation.
DOI:10.64898/2026.03.26.714634 PMID: 41929000 -
White MA, Crowley L, Massenzio F, Li X, Niblock M, Milani S, Coleman MP, Barmada SJ, Sreedharan J. Mol Neurobiol, 2026 Jan 17; 63 (1): 370Journal ArticleInhibiting Glycogen Synthase Kinase 3 Suppresses TDP-43-Mediated Neurotoxicity in a Caspase-Dependent Manner.
DOI:10.1007/s12035-026-05675-5 PMID: PMC12812098 -
Olzinski M, Downer J, Cobigo Y, Rajbanshi B, Li J, Loureiro J, Worringer KA, Heuer H, Ljubenkov P, Vandevrede L, Staffaroni A, Lario-Lago A, Leichter D, Wolf A, Wise A, Sanderson-Cimino M, Barragan E, Spina S, Grinberg LT, Seeley WW, Casaletto KB, Kramer J, Ramos EM, Geschwind D, Cook C, Petrucelli L, Forsberg LK, Gendron T, Boeve BF, Perneel J, Rademakers R, Rosen HJ, Saloner R, Boxer AL, Rojas JC, Abdullah MS, Apostolova L, Appleby B, Barmada S, Bayram E, Botha H, Bozoki A, Brushaber D, Clark D, Considine CM, Darby RR, Day GS, Dickerson BC, Dickson D, Domoto-Reilly K, Dwosh E, Faber KM, Fields JA, Fong JC, Foroud T, Galasko DR, Gavrilova R, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Hales CM, Honig LS, Hsiung GYR, Huey ED, Irwin D, Jones DT, Kantarci K, Knopman D, Kolander T, Kornak J, Kremers W, Kwan J, Lapid M, Lee S, Léger GC, Litvan I, Lucente D, Mackenzie IR, Masdeu JC, Massimo L, McGinnis S, McMillan CT, Mendez MF, Mester C, Miyagawa T, Molden J, Onyike C, Pantelyat A, Pascual B, Paulson H, Ramanan V, Rankin KP, Rascovsky K, Rhoads KW, Roberson ED, Savica R, Snyder A, Sullivan AC. JAMA Neurology, 2026 Jan 1;Journal ArticleClinical Associations of Cerebrospinal Fluid TMEM106B in Familial and Sporadic Frontotemporal Dementia
DOI:10.1001/jamaneurol.2026.1927 -
Best MN, Lamp J, Umstead A, Sierra M, Spencer A, Erturk I, Tank EM, Sexton J, Barmada S, Vega IE, Paulson HL. Alzheimer S Dementia the Journal of the Alzheimer S Association, 2025 Dec 1; 21: e102339Journal ArticleBasic Science and Pathogenesis
DOI:10.1002/alz70855_102339 PMID: 41436380 -
Vargas‐González J, Alotibi HA, Cortez K, Dimal NP, Heuer HW, Forsberg LK, Appleby BS, Barmada S, Bozoki A, Clark DG, Cobigo Y, Darby R, Dickerson BC, Domoto‐Reilly K, Galasko DR, Geschwind DH, Ghoshal N, Graff‐Radford NR, Grant IM, Irwin DJ, Hsiung GR, Honig LS, Kantarci K, Leger GC, Litvan I, MacKenzie IR, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman PS, Ramos EM, Roberson ED, Rogalski EJ, Knopman DS, Boeve BF, Boxer AL, Rosen HJ, Tartaglia C. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025 Dec 31; 21 (Suppl 3):Journal ArticleFemale Informants are associated with higher CDR PLUS NACC‐FTLD scores in patients with Frontotemporal Dementia
PMID: PMC12737986
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