Sami J Barmada, MD, PhD

portrait of Sami Jihad Barmada
Angela Dobson Welch and Lyndon Welch Research Professor
Associate Professor of Neurology
Medical School
[email protected]
Available to mentor
Sami J Barmada, MD, PhD
portrait of Sami Jihad Barmada
Associate Professor
  • Center Memberships
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  • Center Memberships

    • Center Member
      Taubman Institute
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Caswell Diabetes Institute

    Recent Publications

    See All Publications
    • Journal Article
      CTE-type tau filaments in Alzheimer's disease with co-morbid LATE-NC.
      Rana JK, Pinarbasi ES, Fernandez MG, Navratna V, Conway KS, Lieberman AP, Barmada SJ, Mosalaganti S. Acta Neuropathol, 2026 Jul 7; 152 (1): DOI:10.1007/s00401-026-03052-z
      PMID: PMC13337903
    • Journal Article
      Isoform-specific steric zippers drive aberrant assembly and mislocalization of shortened TDP-43.
      Copley KE, Dykstra MM, Miller MR, Linsenmeier M, Lai L, Wang Y, Chang Y-W, Barmada SJ, Shorter J. Sci Adv, 2026 Jun 26; 12 (26): eady0256 DOI:10.1126/sciadv.ady0256
      PMID: PMC13292936
    • Journal Article
      ADAR2-Mediated RNA Editing Promotes TDP-43 Nuclear Export and Alters RNA Binding.
      Moore S, Julian DL, Alsop E, Gittings LM, Lorenzini I, McMillan M, Macklin-Isquierdo S, Lehmkuhl E, Kalab P, de Paula Moreira D, Hayes L, Donnelly C, Barmada SJ, Zarnescu DC, Van Keuren-Jensen K, Sattler R. bioRxiv, 2026 Jun 25; DOI:10.64898/2026.06.22.730622
      PMID: PMC13321060
    • Preprint
      Neurodegeneration risk variants promote lysosomal TMEM106B fibril accumulation.
      Replogle JM, Marks JD, Fernandez MG, Yuan H, Yu D, Winters E, Jawahar VM, Deshmukh R, Sutanto R, Kowal I, Frankenfield A, Shi R, Carlomagno Y, Jansen-West K, Todd TW, Kopach A, Sandra Ndayambaje I, Qi YA, Shantaraman A, Pozo-Cabanell I, Sheth U, Yue M, Duong D, Ferguson SM, Bennett DA, Damme M, Boeve BF, Day GS, Kellman B, Skarnes WC, Petersen RC, Josephs KA, Graff-Radford NR, McDonough JA, Prudencio M, Barmada SJ, Zhang Y, Hao L, DeTure M, Rawlinson B, Engelberg-Cook E, Casey MC, Perez N, Dickson DW, Wingo A, Liu Y, Seyfried NT, Wingo TS, Mosalaganti S, Petrucelli L, Ward ME. 2026 Mar 28; DOI:10.64898/2026.03.26.714634
      PMID: 41929000
    • Journal Article
      Inhibiting Glycogen Synthase Kinase 3 Suppresses TDP-43-Mediated Neurotoxicity in a Caspase-Dependent Manner.
      White MA, Crowley L, Massenzio F, Li X, Niblock M, Milani S, Coleman MP, Barmada SJ, Sreedharan J. Mol Neurobiol, 2026 Jan 17; 63 (1): 370 DOI:10.1007/s12035-026-05675-5
      PMID: PMC12812098
    • Journal Article
      Clinical Associations of Cerebrospinal Fluid TMEM106B in Familial and Sporadic Frontotemporal Dementia
      Olzinski M, Downer J, Cobigo Y, Rajbanshi B, Li J, Loureiro J, Worringer KA, Heuer H, Ljubenkov P, Vandevrede L, Staffaroni A, Lario-Lago A, Leichter D, Wolf A, Wise A, Sanderson-Cimino M, Barragan E, Spina S, Grinberg LT, Seeley WW, Casaletto KB, Kramer J, Ramos EM, Geschwind D, Cook C, Petrucelli L, Forsberg LK, Gendron T, Boeve BF, Perneel J, Rademakers R, Rosen HJ, Saloner R, Boxer AL, Rojas JC, Abdullah MS, Apostolova L, Appleby B, Barmada S, Bayram E, Botha H, Bozoki A, Brushaber D, Clark D, Considine CM, Darby RR, Day GS, Dickerson BC, Dickson D, Domoto-Reilly K, Dwosh E, Faber KM, Fields JA, Fong JC, Foroud T, Galasko DR, Gavrilova R, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Hales CM, Honig LS, Hsiung GYR, Huey ED, Irwin D, Jones DT, Kantarci K, Knopman D, Kolander T, Kornak J, Kremers W, Kwan J, Lapid M, Lee S, Léger GC, Litvan I, Lucente D, Mackenzie IR, Masdeu JC, Massimo L, McGinnis S, McMillan CT, Mendez MF, Mester C, Miyagawa T, Molden J, Onyike C, Pantelyat A, Pascual B, Paulson H, Ramanan V, Rankin KP, Rascovsky K, Rhoads KW, Roberson ED, Savica R, Snyder A, Sullivan AC. JAMA Neurology, 2026 Jan 1; DOI:10.1001/jamaneurol.2026.1927
    • Journal Article
      Basic Science and Pathogenesis
      Best MN, Lamp J, Umstead A, Sierra M, Spencer A, Erturk I, Tank EM, Sexton J, Barmada S, Vega IE, Paulson HL. Alzheimer S Dementia the Journal of the Alzheimer S Association, 2025 Dec 1; 21: e102339 DOI:10.1002/alz70855_102339
      PMID: 41436380
    • Journal Article
      Female Informants are associated with higher CDR PLUS NACC‐FTLD scores in patients with Frontotemporal Dementia
      Vargas‐González J, Alotibi HA, Cortez K, Dimal NP, Heuer HW, Forsberg LK, Appleby BS, Barmada S, Bozoki A, Clark DG, Cobigo Y, Darby R, Dickerson BC, Domoto‐Reilly K, Galasko DR, Geschwind DH, Ghoshal N, Graff‐Radford NR, Grant IM, Irwin DJ, Hsiung GR, Honig LS, Kantarci K, Leger GC, Litvan I, MacKenzie IR, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Pressman PS, Ramos EM, Roberson ED, Rogalski EJ, Knopman DS, Boeve BF, Boxer AL, Rosen HJ, Tartaglia C. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025 Dec 31; 21 (Suppl 3):
      PMID: PMC12737986

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