Billy Tsai, PhD
Corydon Ford Legacy Professor
Professor of Cell and Developmental Biology
Medical School
Email:
[email protected]
Available to mentor
Billy Tsai, PhD
Professor
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Qualifications
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Post-doctoral FellowHarvard University, Cambridge, United States
1999 - 2003
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M.S., BiochemistryUniversity of California, Los Angeles, Los Angeles, United States
1993 - 1994
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B.S., BiologyUniversity of California, Los Angeles, Los Angeles, United States
1989 - 1993
Links
Tsai Lab
Recent Publications
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Sarkar R, Reid W, Sutanto R, Tai AW, Tsai B. Plos Pathogens, 2026 Jul 1; 22 (7):Journal ArticleThe Sigma1 ER membrane receptor promotes structural protein folding and genome packaging of dengue virus
DOI:10.1371/journal.ppat.1014347 PMID: 42461861 -
Gohmann L, Tsai B. Plos Pathogens, 2026 Jun 1; 22 (6 June):Journal ArticleSV40 exploits the Nesprin-2-SUN1-KPNA4 axis for stepwise targeting and entry into the host nucleus to promote infection
DOI:10.1371/journal.ppat.1014344 PMID: 42275395 -
Arunagiri A, Haataja L, Alam M, Gleason NF, Mastroianni E, Cheng CY, Bazzi S, Knupp J, Metawea I, Hassan A, Larkin D, Fang D, Tsai B, Qi L, Arvan P. Journal of Clinical Investigation, 2026 Jan 16; 136 (2):Journal ArticleLimiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis
DOI:10.1172/JCI188888 PMID: 41129238 -
Woo TT, Takeo Y, Harwood MC, Houck ET, DiMaio D, Tsai B. Science Advances, 2025 Oct 22; 11 (43):Journal ArticleThe nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection
DOI:10.1126/sciadv.adz6792 PMID: 41124246 -
Pletan M, Wang E, Gohmann L, Tsai B. Journal of Cell Science, 2025 Mar 1; 138 (6):Journal ArticleAn ER-associated structure sequesters misassembled FG-rich nucleoporins to help maintain nuclear pore complex function
DOI:10.1242/jcs.263659 PMID: 40079246 -
Xu X, Bell TW, Le T, Zhao I, Walker E, Wang Y, Xu N, Soleimanpour SA, Russ HA, Qi L, Tsai B, Liu M, Arvan P. Diabetes, 2024 Dec 1; 73 (12): 2034 - 2044.Journal ArticleRole of Sec61a2 Translocon in Insulin Biosynthesis
DOI:10.2337/db24-0115 PMID: 39325584 -
Choi J, Speckhart K, Tsai B, DiMaio D. Mbio, 2024 Nov 1; 15 (11):Journal ArticleRab6a enables BICD2/dynein-mediated trafficking of human papillomavirus from the trans-Golgi network during virus entry
DOI:10.1128/mbio.02811-24 PMID: 39431827 -
Knupp J, Chen YJ, Wang E, Arvan P, Tsai B. Cell Reports, 2024 Aug 27; 43 (8):Journal ArticleSigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy
DOI:10.1016/j.celrep.2024.114619 PMID: 39128005
Featured News & Stories
Department News
New Publication by Tai-Ting Woo (Tsai lab)
Science Advances published "The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection", by Tai-Ting Woo (Tsai lab).
Research News
Two U-M PhD students named to the HHMI Gilliam Fellows Program
Two University of Michigan students and their PhD advisors have been named to the 2025 cohort of the HHMI Gilliam Fellows Program.
Department News
New Publication from the Tsai Lab!
The Journal of Cell Science published "An ER-associated structure sequesters misassembled FG-rich nucleoporins to help maintain nuclear pore complex function" by the Tsai Lab.
Department News
Ryan Baldridge and Billy Tsai received a W.M. Keck Foundation Award
The W.M. Keck Foundation has awarded $1.3M to Assistant Professor Ryan Baldridge, Biological Chemistry, and Corydon Ford Collegiate Professor Billy Tsai, CDB, to develop a next-generation protein degradation technology to revolutionize antiviral treatments for endoplasmic reticulum (ER) dysfunction.
Department News
Ryan Baldridge, PhD, and Billy Tsai, PhD, receive an award from the W. M. Keck Foundation
U-M Medical School researchers Ryan Baldridge, PhD, and Billy Tsai, PhD, are recipients of a $1.3 million grant from the W. M. Keck Foundation.
Department News
New publication by Jeffrey Knupp and Madison Pletan (Tsai Lab)
New publication by Jeffrey Knupp and Madison Pletan (Tsai Lab)
