Elena Stoffel, MD, MPH

Clinical Professor of Internal Medicine and Service Chief

Medical School

Email:

[email protected]

Available to mentor

Elena Stoffel, MD, MPH

Clinical Professor

Center Memberships

Research Overview

Recent Publications

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Center Memberships

Center Member
Rogel Cancer Center
Center Member
Center for Global Health Equity
Center Member
AI and Digital Health Innovation

Research Overview

My clinical and research focus is cancer prevention. I lead the U-M Rogel Cancer Center Cancer Genetics Clinic and coordinate endoscopic surveillance for individuals with genetic susceptibility to gastrointestinal cancers (such as Lynch Syndrome, Familial Adenomatous Polyposis, Herediary Diffuse Gastric Cancer, and Familial Pancreatic Cancer). My research includes study of risk factors for colorectal, gastric, and pancreatic cancers and clinical trials for cancer prevention.

Recent Publications

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Journal Article
ACG Clinical Guideline: Diagnosis and Management of Adenomatous Colorectal Polyposis Syndromes
Mankaney G, Idos GE, Stoffel EM, Weiss JM, Shah S, Qayed E, Harnegie MP, Burke CA. American Journal of Gastroenterology, 2026 Sep 1; 121 (9): 2086 - 2120. DOI:10.14309/ajg.0000000000004105
PMID: 42683623
Journal Article
Multi-kingdom signatures of the gut microbiome in Lynch syndrome: a prospective model for colorectal cancer evolution.
Shirai N, Bhosle A, Nzabarushimana E, Shen J, Yan Y, Kim H, Upreti C, Ananchuensook P, Stoffel E, Kupfer SS, Chung DC, Thompson KN, Drew DA, Stadler ZK, Huttenhower C, Chan AT, Nguyen LH. Gut, 2026 Aug 25; DOI:10.1136/gutjnl-2026-339088
PMID: 42642216
Journal Article
Factors Associated with Gastric Signet Ring Cell Carcinoma in CDH1 Pathogenic Variant Carriers: Report from the GASTRIC Consortium.
Gilad O, Drogan CM, Keel E, Gao G, Swallow C, Govindarajan A, Brar S, Heller M, Apostolico T, Jacobs MF, Gofar K, Dudley B, Karloski E, Lombardi C, Springer M, Saha S, Cox D, Lerner BA, Hanna G, Chertock Y, Khan A, Ertan S, Hilfrank K, Rustgi SD, Singh A, Hall MJ, Llor X, Bansal A, Patel SG, Brand RE, Roberts ME, Stanich PP, Stoffel E, Katona BW, Aronson M, Kupfer SS. Clin Gastroenterol Hepatol, 2026 Aug 16; DOI:10.1016/j.cgh.2026.07.036
PMID: 42604658
Journal Article
Germline testing in urothelial cancer: A narrative review of evidence, guidelines, and testing frameworks.
Monda SM, Else T, Zhu A, Kaffenberger SD, Humble RM, Reichert ZR, Morgan TM, Chandrasekar T, Dominguez-Valentin M, Stoffel EM, Singhal U. Urol Oncol, 2026 Jul 30; DOI:10.1016/j.urolonc.2026.07.004
Preprint
Race and Socioeconomic Status Impact Survival from Early and Late-Onset Colorectal Cancer.
Purrington K, Hsieh M-C, Patil S, Mabvakure B, Ahn J, Zhang R, Ruterbusch JJ, Samdani R, Lee G, Wenzlaff A, Latif S, Dash C, Sartor M, Schwartz AG, Stoffel EM, Rozek LS. 2026 Jun 29; DOI:10.64898/2026.06.24.26356439
PMID: 42428080
Preprint
Somatic Mutation Profiles in Colorectal Cancers Differ by Population.
Mabvakure BM, Promprasert P, Martinez Cruz L, Patil S, Barros J, Hayhurst M, Mohebbi E, de la Caridad Delgado Herrera D, Lee G, Latif S, Williams F, Samdani R, Duttargi A, Berhane B, Besufikad E, Tadesse S, Jibril Suleiman A, Lefante C, Hsieh M-C, Purrington K, Adjei E, Qin T, Sartor M, Stoffel EM, Rozek LS. 2026 Jun 29; DOI:10.64898/2026.06.24.26356431
PMID: 42428056
Preprint
Survival benefits of varying physical activity levels in a heterogeneous colorectal cancer cohort: The Disparities and Cancer Epidemiology (DANCE) study.
Lima SM, Dash C, Ahn J, Zhang R, Post SM, Patil S, Promprasert C, Mabvakure B, Muhsen R, Schwartz AG, Ruterbusch J, Wenzlaff AS, Hseih M-C, Stoffel EM, Purrington KS, Rozek LS. 2026 Jun 25; DOI:10.64898/2026.06.23.26356372
PMID: 42396308
Preprint
Performance of family history-based colorectal cancer screening criteria by race and age at diagnosis in the Disparities and Cancer Epidemiology (DANCE) study.
Purrington KS, Martin C, Wenzlaff AS, Ruterbusch JJ, Patil S, Pandolfi SS, Samayoa I, Schwartz AG, Hsieh M-C, Stoffel EM, Rozek L. 2026 Jun 19; DOI:10.64898/2026.06.16.26355827
PMID: 42369479

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