Elena Stoffel, MD, MPH

 Elena Martinez Stoffel MD
Clinical Professor
Email:
[email protected]
Available to mentor
Elena Stoffel, MD, MPH
Elena Martinez Stoffel MD
Clinical Professor
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Center for Global Health Equity

    Research Overview

    My clinical and research focus is cancer prevention. I lead the U-M Rogel Cancer Center Cancer Genetics Clinic and coordinate endoscopic surveillance for individuals with genetic susceptibility to gastrointestinal cancers (such as Lynch Syndrome, Familial Adenomatous Polyposis, Herediary Diffuse Gastric Cancer, and Familial Pancreatic Cancer). My research includes study of risk factors for colorectal, gastric, and pancreatic cancers and clinical trials for cancer prevention.

    Recent Publications

     See All Publications
    • Journal Article
      Pancreatic Cancer Early Detection Biomarkers for High-Risk Individuals: Insights From the PRECEDE Consortium
      Worthington C, Raitses-Gurevich M, Innamorati G, Hart PA, Wilkie TM, Tau N, Brin D, Yablecovitch D, Laish I, Keith D, Giles K, Permuth JB, Simeone DM, Zogopoulos G, Brand RE, Graff JJ, Earl J, Agarwal N, Amundadottir L, Anderson M, Bansal A, Bauer T, Beyer G, Bi Y, Borazanci E, Brand R, Brentnall T, Burke C, Carpizo D, Chawla S, Chung D, Darabi S, Demeure M, Donahue T, Espinel W, Farrell J, Stefánsdóttir VF, Forrester J, Friedman E, Franklin P, Gaddam S, de Paredes AGG, Gallinger S, Golan T, Gordon O, Grant R, Greenhalf W, Grindedal EM, Grossberg A, Hafers B, Hannon H, Haraldsdóttir S, Haraldsson S, Hegyi P, Hogg M, de Haar-Holleman A, Hong S, Idos G, Kim E, Kastrinos F, Katona B, Kaul V, Klatte D, Klute K, Ku K, Kupfer S, Kwon R, Ligresti R, Lin JJ, Liao WC, Lucas A, Merchant N, Metz A, Maxwell W, McLoughlin J, Miclette S, Molero X, Moreira L, Morizane TOC, Ngeow J, Paiella S, Permuth J, Purcell M, Raff J, Rolston V, Schrader I, Sears R, Shan YS, Simeone D, Siveke J, Sheppard B, Stevens T, Stoffel E, Sussman D, Tempero M, Trevino J, Valerin J, Vaquero E, Wadlow R. International Journal of Cancer, 2026 Oct 15; 159 (8): 1873 - 1883. DOI:10.1002/ijc.70592
      PMID: 42298760
    • Journal Article
      INCREASED PREVALENCE OF PANCREATIC CYSTS IN NONSECRETOR (FUT2 NULL) INDIVIDUALS UNDER PANCREATIC SURVEILLANCE.
      Hozaka Y, Hayashi M, Abou Sleiman E, Katona BW, Brand RE, Syngal S, Yurgelun MB, Farrell JJ, Chak A, Stoffel EM, Gonda TA, Dbouk M, Afghani E, He J, Hruban RH, Eshleman JR, Canto MI, Goggins MG. Cancer Epidemiol Biomarkers Prev, 2026 Oct 8; DOI:10.1158/1055-9965.EPI-26-0807
      PMID: 42847802
    • Journal Article
      Serrated Polyposis Syndrome: A Review and Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer.
      Rex DK, Anderson JC, Burke CA, Jacobson BC, May FP, Patel SG, Samadder NJ, Stoffel EM, Robertson DJ. Gastroenterology, 2026 Sep 30; DOI:10.1053/j.gastro.2026.09.001
      PMID: 42814045
    • Preprint
      Epigenetic Exposure Signatures Distinguish Early-Onset from Later-Onset Colorectal Cancer in a Racially Diverse US Cohort: Findings from the Disparities and Cancer Epidemiology (DANCE) Study.
      Lima SM, Ahn J, Dash C, Hseih M-C, Jones RR, Mabvakure B, Muhsen R, Patil S, Peluso A, Promprasert C, Qin T, Ruterbusch JJ, Sartor MA, Schwartz AG, Wenzlaff AS, Zhang R, Stoffel EM, Purrington KS, Rozek LS. 2026 Sep 29; DOI:10.64898/2026.09.28.26363311
      PMID: 42856386
    • Journal Article
      ACG Clinical Guideline: Diagnosis and Management of Adenomatous Colorectal Polyposis Syndromes (10.14309/ajg.0000000000004160)
      Mankaney G, Idos GE, Stoffel EM, Weiss JM, Shah S, Qayed E, Harnegie MP, Burke CA. American Journal of Gastroenterology, 2026 Sep 1; 121 (9): 2086 - 2120. DOI:10.14309/ajg.0000000000004105
      PMID: 42683623
    • Journal Article
      Multi-kingdom signatures of the gut microbiome in Lynch syndrome: a prospective model for colorectal cancer evolution.
      Shirai N, Bhosle A, Nzabarushimana E, Shen J, Yan Y, Kim H, Upreti C, Ananchuensook P, Stoffel E, Kupfer SS, Chung DC, Thompson KN, Drew DA, Stadler ZK, Huttenhower C, Chan AT, Nguyen LH. Gut, 2026 Aug 25; DOI:10.1136/gutjnl-2026-339088
      PMID: 42642216
    • Journal Article
      Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death
      Jain C, Essani M, Kumar R, Das NK, Singhal R, Rossiter NJ, Chen B, Huang W, Lee ZH, Solanki S, Zhang Y, Sajjakulnukit P, Zhang L, Dalal PJ, Hanna DA, Castillo C, Greenbaum HS, McCollum SE, Stoffel EM, Greenson JK, Maher LJ, Lyssiotis CA, Banerjee R, Shah YM. Cell Metabolism, 2026 Aug 4; 38 (8): 1599 - 1617.e8. DOI:10.1016/j.cmet.2026.04.020
      PMID: 42202783
    • Journal Article
      Phase II Trial of Encapsulated Rapamycin to Reduce Polyp Burden Associated with Familial Adenomatous Polyposis
      Broderick JC, Samadder NJ, Stoffel E, Fang JC, Stanich PP, Wise P, Wright R, Clifton T, Peoples G, Burke CA. Clinical Cancer Research, 2026 Aug 1; 32 (15): 3146 - 3156. DOI:10.1158/1078-0432.CCR-25-4126
      PMID: 42048421

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