Chandra Sripada, MD, PhD

portrait of Chandra Sripada
Theophile Raphael Research Professor of Clinical Neurosciences
Professor of Psychiatry, Medical School
Professor of Philosophy
Professor of Weinberg Institute for Cognitive Science and Director Academic Program
Linguistics, College of Literature, Science, and the Arts
Available to mentor
Chandra Sripada, MD, PhD
portrait of Chandra Sripada
Professor
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  • About

    Dr. Sripada’s research investigates neurocognition, executive functions, and regulatory control across a range of psychiatric disorders, especially attention-deficit/hyperactivity disorder and substance use disorders. His research uses multiple methods, especially neuroimaging and computational methods, to better understand, diagnose, and treat these conditions. Important themes of recent work include: 1) connectomics – mapping structural and functional networks encompassing hundreds of thousands of connections across the brain; 2) multivariate methodology – quantifying distributed patterns associated with disorders using methods from statistics and computer science; 3) developmental focus – mapping altered maturational trajectories of brain networks in youth. Recent articles appeared in PNAS, Journal of Neuroscience, and JAMA Psychiatry, and are available at Sripada’s lab website.

    Areas of Interest

    - Adult Attention Deficit/Hyperactivity Disorder
    - Substance Use Disorders
    - Adult Attention Deficit/Hyperactivity Disorder
    - Substance Use Disorders
    - Functional Neuroimaging

    Center Memberships

    • Center Member
      Eisenberg Family Depression Center
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      AI and Digital Health Innovation

    Recent Publications

    See All Publications
    • Journal Article
      Delayed goal-directed processing underlies inhibitory control challenges in adult ADHD
      Osborne JB, Sellers J, Zhang H, Wang S, Liberatore S, Sripada C, Shah P, Jonides J. Scientific Reports, 2026 Dec 1; 16 (1): DOI:10.1038/s41598-026-42307-3
      PMID: 41840046
    • Journal Article
      Scalable, context-sensitive psychiatric assessment with large language models and brief diaries
      Ringwald WR, Taxali A, Angstadt M, Vize CE, Sripada C, Wright AGC. Psychological Medicine, 2026 Jul 21; 56: DOI:10.1017/S0033291726105261
      PMID: 42478221
    • Journal Article
      Large language models illuminate the mechanistic underpinnings of the creative aspect of language use (CALU), long regarded as a mystery
      Sripada C, Mcinnerney A, Lewis RL. Behavioral and Brain Sciences, 2026 Jul 1; 49: DOI:10.1017/S0140525X26104725
      PMID: 42380017
    • Journal Article
      The Roles of Delayed Cortical Maturation and Lower Anticipatory Reward Activation in Predicting Addictive Screen Use in Youth
      Paige KJ, Angstadt M, Martz ME, Hyde LW, Heitzeg MM, Sripada C, Kardan O. Biological Psychiatry Cognitive Neuroscience and Neuroimaging, 2026 Jul 1; 11 (7): 824 - 832. DOI:10.1016/j.bpsc.2026.03.012
      PMID: 41905476
    • Journal Article
      Joint Cognitive Models Reveal Sources of Robust Individual Differences in Conflict Processing
      Molloy MF, Lee TG, Jonides J, Zhang H, Sellers J, Heathcote A, Sripada C, Weigard AS. Computational Brain and Behavior, 2026 Jun 1; 9 (2): 319 - 336. DOI:10.1007/s42113-026-00263-1
    • Preprint
      Sparse Feature Coactivation Reveals Causal Semantic Modules in Large Language Models
      Deng R, Hu X, Gilberti M, Storks S, Taxali A, Angstadt M, Sripada C, Chai J. 2025 Jun 25; arXiv, DOI:10.48550/arxiv.2506.18141
    • Journal Article
      An AI-powered research assistant in the lab: A practical guide for text analysis through iterative collaboration with LLMs
      Carmona-Díaz G, Jiménez-Leal W, Grisales MA, Sripada C, Amaya S, Inzlicht M, Bermúdez JP. Behavior Research Methods, 2026 Apr 1; 58 (4): DOI:10.3758/s13428-026-02966-6
      PMID: 41912832
    • Journal Article
      Decreased sleep is linked longitudinally and directionally to alterations in the brain's intrinsic functional architecture
      Molloy MF, Taxali A, Angstadt M, Toda-Thorne K, McCurry KL, Weigard A, Kardan O, Lehrmann C, Vens J, Michael C, Heitzeg MM, Sripada C. Developmental Cognitive Neuroscience, 2026 Apr 1; 78: DOI:10.1016/j.dcn.2025.101668
      PMID: 41496291

    Featured News & Stories

    a contact sheet of various brain scans shown at an angle
    Department News

    Psychiatry experts' research highlighted in U-M VP of Research's Michigan Research newsletter

    The newsletter featured research by Drs. Amy Bohnert and Srijan Sen; Mark Ilgen; and Mary Heitzeg and Chandra Sripada
    Illustration of person swinging from a tree on a swing made of DNA. A version of the same person is sitting at the base of the tree with their head down.
    Medicine at Michigan

    Searching for the biology of mental illness

    For half a century, Michigan Medicine researchers have been working to understand why we feel the way we feel. Their findings have offered hope to patients with mental health conditions from anxiety and depression to addiction and bipolar disorder.