Yuanfang Guan, PhD
Professor of Computational Medicine and Bioinformatics
Professor of Internal Medicine
gyuanfan@umich.edu

Available to mentor

Yuanfang Guan, PhD
Professor
  • Qualifications
  • Research Overview
  • Links
  • Recent Publications
  • Qualifications
    • Ph.D., Molecular Biology
      Princeton University, Princeton, NJ, 2010
    • BS, Biology
      The University of Hong Kong, Hong Kong, 2005
    Research Overview

    The Guan lab's research focus is machine learning in biology and medical fields.

    Links
    • Guan Lab
    Recent Publications See All Publications
    • Journal Article
      Predicting Single Neuron Responses of the Primary Visual Cortex with Deep Learning Model.
      Deng K, Schwendeman PS, Guan Y. Adv Sci (Weinh), 2024 Apr; 11 (15): e2305626 DOI:10.1002/advs.202305626
      PMID: 38350735
    • Journal Article
      ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice.
      Schuster KH, Zalon AJ, DiFranco DM, Putka AF, Stec NR, Jarrah SI, Naeem A, Haque Z, Zhang H, Guan Y, McLoughlin HS. Mol Ther, 2024 May 1; 32 (5): 1359 - 1372. DOI:10.1016/j.ymthe.2024.02.033
      PMID: 38429929
    • Journal Article
      Assessing the impact of body location on the accuracy of detecting daily activities with accelerometer data.
      Dang X, Li W, Zou J, Cong B, Guan Y. iScience, 2024 Feb 16; 27 (2): 108626 DOI:10.1016/j.isci.2023.108626
      PMID: 38318391
    • Journal Article
      Artificial intelligence approaches for molecular representation in drug response prediction.
      Lin C-X, Guan Y, Li H-D. Curr Opin Struct Biol, 2024 Feb; 84: 102747 DOI:10.1016/j.sbi.2023.102747
      PMID: 38091924
    • Journal Article
      A community effort to optimize sequence-based deep learning models of gene regulation.
      Rafi AM, Nogina D, Penzar D, Lee D, Lee D, Kim N, Kim S, Kim D, Shin Y, Kwak I-Y, Meshcheryakov G, Lando A, Zinkevich A, Kim B-C, Lee J, Kang T, Vaishnav ED, Yadollahpour P, Random Promoter DREAM Challenge Consortium , Kim S, Albrecht J, Regev A, Gong W, Kulakovskiy IV, Meyer P, de Boer CG. Nat Biotechnol, 2024 Oct 11; DOI:10.1038/s41587-024-02414-w
      PMID: 39394483
    • Journal Article
      Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction.
      Salcedo A, Tarabichi M, Buchanan A, Espiritu SMG, Zhang H, Zhu K, Ou Yang T-H, Leshchiner I, Anastassiou D, Guan Y, Jang GH, Mootor MFE, Haase K, Deshwar AG, Zou W, Umar I, Dentro S, Wintersinger JA, Chiotti K, Demeulemeester J, Jolly C, Sycza L, Ko M, PCAWG Evolution and Heterogeneity Working Group , SMC-Het Participants , Wedge DC, Morris QD, Ellrott K, Van Loo P, Boutros PC. Nat Biotechnol, 2024 Jun 11; DOI:10.1038/s41587-024-02250-y
      PMID: 38862616
    • Journal Article
      TR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms.
      Wang Y, Myers G, Yu L, Deng K, Balbin-Cuesta G, Singh SA, Guan Y, Khoriaty R, Engel JD. Blood, 2024 Oct 11; DOI:10.1182/blood.2024024599
      PMID: 39393056
    • Journal Article
      Harmonizing across datasets to improve the transferability of drug combination prediction.
      Zhang H, Wang Z, Nan Y, Zagidullin B, Yi D, Tang J, Guan Y. Commun Biol, 2023 Apr 11; 6 (1): 397 DOI:10.1038/s42003-023-04783-5
      PMID: 37041243
    Featured News & Stories Photos of DCMB promoted faculty: Yuanfang Guan, Ph.D., Jie Liu, Ph.D., Ryan Mills, Ph.D., Stephen C.J. Parker, Ph.D., and Arvind Rao, Ph.D.
    Department News
    Five DCMB faculty are promoted, congratulations!
    Five DCMB faculty were promoted. They are Yuanfang Guan, Ph.D., Jie Liu, Ph.D., Ryan Mills, Ph.D., Stephen C.J. Parker, Ph.D., and Arvind Rao, Ph.D. Congratulations!