Michael Mathis, MD
Associate Professor of Anesthesiology and Program Director
Anesthesiology
Anesthesiology
1500 E Medical Center Drive
Ann Arbor, MI 48109
[email protected]

Available to mentor

Michael Mathis, MD
Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Michael Mathis, MD is an Associate Professor of Anesthesiology in the Division of Adult Cardiac Anesthesia at the University of Michigan. After completing his undergraduate degree in Biomedical Engineering at Duke University in 2006, Dr. Mathis received his MD from University of Michigan in 2010 and completed his residency in Anesthesiology and fellowship in Adult Cardiothoracic Anesthesiology at University of Michigan. He also completed an NIH T32 research fellowship sponsored by the Department of Anesthesiology at University of Michigan.

    Dr. Mathis seeks to improve perioperative care of patients with advanced cardiovascular disease, through the use of data science techniques applied to real-world electronic health data. He serves as the Research Director for the Multicenter Perioperative Outcomes Group spanning US academic and community hospitals, amassing data electronic anesthesiology records for research and quality improvement.

    Links
    • Multicenter Perioperative Outcomes Group
    Qualifications
    • MD
      University of Michigan, 1500 East Medical Center Drive, 2010
    • BSE
      Duke University, Durham, 2006
    Center Memberships
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Precision Health Initiative
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      e-Health and Artificial Intelligence Initiative
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    Research Overview

    Dr. Mathis has research interests in improving perioperative care for patients with advanced cardiovascular disease, particularly for patients with heart failure. As part of the Multicenter Perioperative Outcomes Group (MPOG), an international consortium of perioperative databases for which U-M serves as the coordinating center, he serves as Research Director and plays a lead role in integration of MPOG data with data from national cardiac and thoracic surgery registries. He also has interests in leveraging novel data science methods to understand patterns within highly granular intraoperative physiologic data, studying hemodynamic responses to surgical and anesthetic stimuli as a means for early detection of cardiovascular diseases such as heart failure.

    Dr. Mathis is an Affiliated Faculty within the Center of Computational Medicine and Bioinformatics (CCMB), member of the Michigan Integrated Center for Health Analytics & Medical Prediction (MiCHAMP) and member of the Institute for Health Policy and Innovation (IHPI). He has received research funding from the NIH, Department of Defense, and the BCBS Foundation of Michigan.

    Recent Publications See All Publications
    • Journal Article
      Heart failure diagnostic accuracy, intraoperative fluid management, and postoperative acute kidney injury: a single-centre prospective observational study.
      Mathis MR, Ghadimi K, Benner A, Jewell ES, Janda AM, Joo H, Maile MD, Golbus JR, Aaronson KD, Engoren MC, Michigan Congestive Heart Failure Investigators . Br J Anaesth, 2024 Oct 9; DOI:10.1016/j.bja.2024.08.020
      PMID: 39389834
    • Journal Article
      The Association of Oxygen Delivery and Transfusion on Cardiopulmonary Bypass with Acute Kidney Injury.
      Engoren M, Janda A, Heung M, Sturmer D, Likosky DS, Hawkins RB, Do-Nguyen CC, Mathis M. J Cardiothorac Vasc Anesth, 2024 Sep; 38 (9): 1914 - 1922. DOI:10.1053/j.jvca.2024.04.019
      PMID: 38890088
    • Presentation
      Guidelines on Using Machine Learning for Clinical Applications
      Mathis M. 2024 Jul 12;
    • Presentation
      Using Machine Learning for Clinical & Health Applications
      Mathis M. 2024 Jul 9;
    • Journal Article
      Preoperative passive venous pressure-driven cardiac function determines left ventricular assist device outcomes.
      Tang PC, Millar J, Noly PE, Sicim H, Likosky DS, Zhang M, Pagani FD, Michigan Congestive Heart Failure Investigators . J Thorac Cardiovasc Surg, 2024 Jul; 168 (1): 133 - 144.e5. DOI:10.1016/j.jtcvs.2023.07.019
      PMID: 37495169
    • Journal Article
      An Evolving Framework for Using Big Data Tools and Machine Learning to Enhance Perioperative Quality Improvement, Research, and Patient Safety
      Burns M, Mathis M, Shah N, Edelman A, Janda A, Colquhoun D, Schonberger R. APSF Newsletter, 2024 Jun 17; 39 (2):
    • Journal Article
      Anesthesia Techniques for Vitreoretinal Surgery in the United States: A Report from the Multicenter Perioperative Outcomes Group Research Consortium.
      Chauhan MZ, Soliman MK, Pace NL, Mathis MR, Schonberger RB, Sallam AB, MPOG Investigator Group . Am J Ophthalmol, 2024 Jun 12; 267: 30 - 40. DOI:10.1016/j.ajo.2024.06.010
      PMID: 38871268
    • Additional Scholarship
      An Evolving Framework for Using Big Data Tools and Machine Learning to Enhance Perioperative Quality Improvement, Research, and Patient Safety
      Colquhoun D, Mathis MR, Schonberger RB, Edelman AL, Janda A, Burns ML, Shah N. 2024 Jun 1;
    Featured News & Stories Michael Mathis
    Department News
    Michael Mathis, MD, awarded NIH grant to compare inotrope practice variation in cardiac surgery
    A new study led by Michael Mathis, MD, is setting out to better understand variation in inotrope decision-making and outcomes across hospitals, as well as the barriers and facilitators to inotrope practice change. Mathis recently received National Institutes of Health funding through the National Heart, Lung and Blood Institute to support this research.
    Department News
    Fourteen faculty promotions announced
    The University of Michigan Regents approved 14 Department of Anesthesiology faculty promotions during their May 2023 meeting. Promotions will go into effect September 1.
    Department News
    Department receives perioperative transesophageal echocardiography accreditation by IAC
    IAC accreditation is a “seal of approval” and indicator to patients of consistent quality care and a dedication to continuous improvement.