Rachel Lynne Zemans, MD
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About
Rachel received her BS in Biological Sciences and MA in Philosophy from Stanford University. She received her MD from Johns Hopkins University, completed a residency in Internal Medicine at UCSF and a fellowship in Pulmonary & Critical Care Medicine at the University of Colorado. She was on the faculty at National Jewish Health and the University of Colorado for 10 years before moving to the University of Michigan, where she is currently the Henry Sewall Research Professor in the Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, and a member of the Cellular and Molecular Biology faculty. Her research focuses on mechanisms of regeneration of the alveolar epithelium after lung injury and how regeneration may be impaired in lung disease. Her work has been funded by many NIH and foundation grants and has been published in PNAS, the American Journal of Respiratory and Critical Care Medicine, JCI Insight, and JCI. She was the recipient of a Parker B. Francis Fellowship and the American Thoracic Society Early Career Achievement Award and is an elected member of the American Society of Clinical Investigation. Rachel serves on numerous national and international committees, study sections, and editorial boards.
Center Memberships
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberBiosciences Initiative
Recent Publications
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Zemans R. 2026 May 31;PresentationTBD
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Zemans R. 2026 May 31;PresentationMechanisms of Transitional Alveolar Epithelial States in Lung Injury and Disease
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Maddali MV, Pugashetti JV, Pienkos SM, Moore AR, Konkol SB, Kim JS, Ma SF, Newton CA, Garcia CK, Adegunsoye A, Strek ME, Chen CH, Linderholm AL, Zemans RL, Moore BB, Wolters PJ, Raj R, Chen JH, Martinez FJ, Noth I, Rogers AJ, Oldham JM. American Journal of Respiratory and Critical Care Medicine, 2026 Apr 1; 212 (4): 768 - 777.Journal ArticleMolecular endotypes predict differential response to immunosuppressant therapy in non-idiopathic pulmonary fibrosis interstitial lung disease
DOI:10.1093/ajrccm/aamag006 PMID: 41738192 -
Zemans R. 2026 May 31;PresentationTBD
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Sarma A, Sun X, Sucre J, Hong J, Medzikovic L, Jakubzick CV, Li X, Zemans RL, Singer BD. American Journal of Respiratory Cell and Molecular Biology, 2026 Mar 1; 74 (3): 287 - 294.Journal ArticleMulti-Omic and Single-Cell Approaches for Elucidating Cell Biology and Pathobiology of Lung Disease
DOI:10.1165/rcmb.2025-0092PS PMID: 40700713 -
Sarma A, Sun X, Sucre J, Hong J, Medzikovic L, Jakubzick CV, Li X, Zemans RL, Singer BD. American Journal of Respiratory Cell and Molecular Biology, 2026 May 31; 74 (3): 287 - 294.Journal ArticleMulti-Omic and Single-Cell Approaches for Elucidating Cell Biology and Pathobiology of Lung Disease
DOI:10.1165/rcmb.2025-0092ps -
Redente EF, Song T, Javkhlan N, Edelman BL, Foster DG, Wilson JA, Chakraborty S, Cooley JC, Gaurav R, Saguthi S, Seibold MA, Blumhagen RZ, Schwartz DA, Yang IV, Matsuda J, Bridges JP, Zemans RL, Tuder RM, Riches DWH. Nat Commun, 2026 Feb 28;Journal ArticleConditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition.
DOI:10.1038/s41467-026-69865-4 PMID: 41764163 -
Oldham J, Molyneaux P, Maddali M, Newton C, Kim J, Konkol S, Pugashetti J, Liu G, Goobie G, Adegunsoye A, Ma S-F, Bornstein D, Murray S, Wain L, Saini G, Stewart I, Johnson S, Jenkins G, Strek M, Linderholm A, Chen C-H, Fahy W, Zemans R, Moore B, Khanna D, Ryerson C, Flaherty K, Suresh M, Hoffmann-Vold A-M, Maher T, Garcia C, Wolters P, Martinez F, Noth I, Smith JA. Res Sq, 2026 Feb 5;Journal ArticlePrioritizing Therapeutic Targets for Interstitial Lung Disease: A Causal Mediation Analysis.
DOI:10.21203/rs.3.rs-8714555/v1 PMID: PMC12889817
