Frederick Korley, MD, PhD
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About
Dr. Korley is a Professor and the Executive Vice-Chair of Emergency Medicine at the University of Michigan. He is also the scientific director of the Massey TBI Grand Challenge, sponsored by the Weil Institute at the University of Michigan. This challenge distributes up to $750,000 annually to investigators with high-risk and high-reward ideas for developing novel diagnostics and therapeutics for traumatic brain injury (TBI).
He completed his medical degree and residency training in emergency medicine at Northwestern University, where he served as chief resident. Subsequently, he completed a doctoral degree in clinical investigation at the Johns Hopkins University Bloomberg School of Public Health and was elected to Phi Beta Kappa. He was formerly on faculty at Johns Hopkins University where he was the inaugural recipient of the Robert E. Meyerhoff Endowed Professorship.
Dr. Korley has conducted pioneering work in uncovering and quantifying gaps in emergency department evaluation and management of traumatic brain injury (TBI) and has developed novel diagnostic and therapeutic approaches to bridge these gaps. He is a PI of several NIH and Department of Defense-funded studies that aim to develop novel therapies for TBI and to use blood-based biomarkers to monitor response to therapy. He holds four patents for panels of brain‑injury biomarkers and the methods used to measure them at the bedside. Dr. Korley’s research has been published as first-author manuscripts in high-impact journals such as NEJM, JAMA, JAMA Cardiology, Journal of the American College of Cardiology, and Lancet Neurology. He is the recipient of the 2021 SAEM Mid-Career Investigator Award. He is an elected member of the American Society for Clinical Investigation and the National Academy of Medicine.
Qualifications
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KL2 Clinical Research ScholarJohns Hopkins Institute for Clinical and Translational Research, Baltimore, United States
2010 - 2012
Postdoctoral Research
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Emergency MedicineNorthwestern University Feinberg School of Medicine, Department of Emergency Medicine, Chicago, United States
2003 - 2007
Residency
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Emergency MedicineNorthwestern University Feinberg School of Medicine, Emergency Medicine, Chicago, United States
2006 - 2007
Chief Resident
Center Memberships
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Center MemberUniversity of Michigan Injury Prevention Center
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Center MemberWeil Institute for Critical Care Research
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Center MemberCenter for Computational Medicine and Bioinformatics
Research Overview
• Development of Novel Diagnostics and Therapeutics for Traumatic Brain Injury
• Building an Emergency Medicine Learning Health System
Recent Publications
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Yue JK, Fu AY, Jain S, Puccio AM, Eagle SR, Korley FK, van Essen TA, Samanta R, Li LM, Roberts CJ, Caldwell DJ, Elguindy MM, Vassar MJ, Belton PJ, Bhattacharyay S, Nelson LD, Tracey JX, Etemad LL, Gotthardt CJ, Satris GG, Wang MB, Demos C, Sigal GB, Amorim E, Madhok DY, Radabaugh HL, Ferguson AR, Markowitz AJ, Robertson CS, Valadka AB, Mukherjee P, Yuh EL, McCrea MA, Hinson HE, Schneider ALC, Sun X, Okonkwo DO, Kobeissy FH, Manley GT, Diaz-Arrastia R, Wang KKW, Zafonte RD, Wohlstadter JN, Tran TT, Temkin NR, Taylor SR, Stein MB, Schnyer DM, Rodgers RB, Park KS, Padmanabhan N, Ngwenya LB, Neely C, Merchant R, Menon DK, Martell D, Mannix R, Mac Donald CL, Lingsma HF, Krishnamoorthy V, Jha RM, Huie JR, Grandhi R, Gorham T, Giacino JT, Foreman B, Fabian B, Duhaime AC, Chesnut RM, Brophy GM. Journal of Neuroinflammation, 2026 Dec 1; 23 (1):Journal ArticleInflammatory blood-based biomarkers to aid in the assessment and prognostication of traumatic brain injury: a TRACK-TBI study
DOI:10.1186/s12974-026-03891-3 PMID: 42210282 -
Boyd M, Potocki C, Korley F, Gherasim C. Clinical Chemistry, 2026 Oct 5; 72 (Supplement_1): hvag086.293Journal ArticleA-359 Comparison of Whole Blood and Plasma GFAP and UCH-L1 Blood-Based Biomarkers for Screening Patients with Mild Traumatic Brain Injury
DOI:10.1093/clinchem/hvag086.293 -
Roberts NB, Gherasim C, Li K, Xie T, Falk H, Bapuraj J, Demski D, Fung CM, Haas NL, Kocher KE, Seagly KS, Medlin RP, Joseph J, Schipper MJ, Chandran R, Marino JA, McQuiston B, Pradhan-Bhatt S, Korley FK. J Appl Lab Med, 2026 Sep 10;Journal ArticleComparability of GFAP and UCH-L1 Measurements Using Handheld and Core Laboratory TBI Plasma Tests and Their Diagnostic Performance for Traumatic Intracranial Lesions.
DOI:10.1093/jalm/jfag093 PMID: 42720066 -
Haas NL, Korley FK, Schneider RM, Mamillapalli SL, Hepworth E, Cranford JA, Lin YK, Griffey RT. Diabetes Technology and Therapeutics, 2026 Sep 1; 28 (9): 992 - 998.Journal ArticleContinuous Ketone Monitoring in Diabetic Ketoacidosis: Prospective Multicenter Method-Comparison and Feasibility Study
DOI:10.1177/15209156261428034 PMID: 41800718 -
Wongsripuemtet P, Dong K, Vavilala MS, Miller JB, Minic Z, Ohnuma T, Laskowitz D, Goldstein B, Korley F, Meurer W, Kaakati A, Chaikittisilipa N, Kiatchai T, Wang Z, Hu X, Krishnamoorthy V. Anesthesia and Analgesia, 2026 Sep 1; 143 (3): 662 - 665.Journal ArticleEarly Autonomic Dysfunction After Severe Traumatic Brain Injury: A Brief Report
DOI:10.1213/ANE.0000000000008019 PMID: 41910955 -
Roberts NB, Xie T, Falk H, Bapuraj J, Demski D, Gherasim C, Fung CM, Haas NL, Kocher KE, Seagly KS, Medlin RP, Kallabat A, Askar A, Joseph J, Schipper MJ, Korley FK. Annals of Emergency Medicine, 2026 May 1; 87 (5): 640 - 649.Journal ArticleGlial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase L1 for Acute Traumatic Intracranial Lesions: The PIONEER Diagnostic Accuracy Study
DOI:10.1016/j.annemergmed.2025.09.012 PMID: 41071136 -
Mamer L, Korley F, Zahuranec D, Scott P. Stroke, 2026 Jan 31; 57 (Suppl_1):Proceeding / Abstract / PosterAbstract WP370: Potential of Plasma GFAP to Rule Out Minor Stroke in Low-Risk Emergency Department Patients
DOI:10.1161/str.57.suppl_1.wp370 -
Bharadwaj MS, Krishnamoorthy V, Miller JB, Vavilala M, Hu X, Dong K, Laskowitz D, Korley F, Meurer W, Minic Z. Anesthesiology, 2026 Jan 1;Journal ArticleAnalyzing Heart Rate Variability in Critical Illness: Contemporary and Emerging Methods
DOI:10.1097/ALN.0000000000006168 PMID: 42644480
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