Frederick Korley, MD, PhD
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About
Dr. Korley is a Professor and the Associate Chair for Research in Emergency Medicine at the University of Michigan. He is also the scientific director of the Massey TBI Grand Challenge, sponsored by the Weil Institute at the University of Michigan. This challenge distributes up to $750,000 annually to investigators with high-risk and high-reward ideas for developing novel diagnostics and therapeutics for traumatic brain injury (TBI).
He completed his medical degree and residency training in emergency medicine at Northwestern University, where he served as chief resident. Subsequently, he completed a doctoral degree in clinical investigation at the Johns Hopkins University Bloomberg School of Public Health and was elected to Phi Beta Kappa. He was formerly on faculty at Johns Hopkins University where he was the inaugural recipient of the Robert E. Meyerhoff Endowed Professorship.
Dr. Korley has conducted pioneering work in uncovering and quantifying gaps in emergency department evaluation and management of traumatic brain injury (TBI) and has developed novel diagnostic and therapeutic approaches to bridge these gaps. He is a PI of several NIH and Department of Defense-funded studies that aim to develop novel therapies for TBI and to use blood-based biomarkers to monitor response to therapy. He holds four patents for panels of brain‑injury biomarkers and the methods used to measure them at the bedside. Dr. Korley’s research has been published as first-author manuscripts in high-impact journals such as NEJM, JAMA, JAMA Cardiology, Journal of the American College of Cardiology, and Lancet Neurology. He is the recipient of the 2021 SAEM Mid-Career Investigator Award. He is an elected member of the American Society for Clinical Investigators and the National Academy of Medicine.
Qualifications
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KL2 Clinical Research ScholarJohns Hopkins Institute for Clinical and Translational Research, Baltimore, United States
2010 - 2012
Postdoctoral Research
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Emergency MedicineNorthwestern University Feinberg School of Medicine, Department of Emergency Medicine, Chicago, United States
2003 - 2007
Residency
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Emergency MedicineNorthwestern University Feinberg School of Medicine, Emergency Medicine, Chicago, United States
2006 - 2007
Chief Resident
Center Memberships
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Center MemberUniversity of Michigan Injury Prevention Center
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Center MemberWeil Institute for Critical Care Research
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Center MemberCenter for Computational Medicine and Bioinformatics
Research Overview
• Development of Novel Diagnostics and Therapeutics for Traumatic Brain Injury
• Building an Emergency Medicine Learning Health System
Recent Publications
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Yue JK, Fu AY, Jain S, Puccio AM, Eagle SR, Korley FK, van Essen TA, Samanta R, Li LM, Roberts CJ, Caldwell DJ, Elguindy MM, Vassar MJ, Belton PJ, Bhattacharyay S, Nelson LD, Tracey JX, Etemad LL, Gotthardt CJ, Satris GG, Wang MB, Demos C, Sigal GB, Amorim E, Madhok DY, Radabaugh HL, Ferguson AR, Markowitz AJ, Robertson CS, Valadka AB, Mukherjee P, Yuh EL, McCrea MA, Hinson HE, Schneider ALC, Sun X, Okonkwo DO, Kobeissy FH, Manley GT, Diaz-Arrastia R, Wang KKW, TRACK-TBI Investigators . J Neuroinflammation, 2026 May 28;Journal ArticleInflammatory blood-based biomarkers to aid in the assessment and prognostication of traumatic brain injury: a TRACK-TBI study.
DOI:10.1186/s12974-026-03891-3 PMID: 42210282 -
Wongsripuemtet P, Dong K, Vavilala MS, Miller JB, Minic Z, Ohnuma T, Laskowitz D, Goldstein B, Korley F, Meurer W, Kaakati A, Chaikittisilipa N, Kiatchai T, Wang Z, Hu X, Krishnamoorthy V. Anesth Analg, 2026 Mar 30;Journal ArticleEarly Autonomic Dysfunction After Severe Traumatic Brain Injury: A Brief Report.
DOI:10.1213/ANE.0000000000008019 PMID: 41910955 -
Haas NL, Korley FK, Schneider RM, Mamillapalli SL, Hepworth E, Cranford JA, Lin YK, Griffey RT. Diabetes Technol Ther, 2026 Mar 9; 15209156261428034Journal ArticleContinuous Ketone Monitoring in Diabetic Ketoacidosis: Prospective Multicenter Method-Comparison and Feasibility Study.
DOI:10.1177/15209156261428034 PMID: 41800718 -
Mamer L, Korley F, Zahuranec D, Scott P. Stroke, 2026 Jan 31; 57 (Suppl_1):Journal ArticleAbstract WP370: Potential of Plasma GFAP to Rule Out Minor Stroke in Low-Risk Emergency Department Patients
DOI:10.1161/str.57.suppl_1.wp370 -
Rahman MM, Saif MSI, Beall J, Martin RL, Rockswold GL, Barsan WG, Korley FK, Silbergleit R, Stevenson V, Gajewski B. Contemporary Clinical Trials Communications, 2025 Dec 1; 48:Journal ArticleA Bayesian model with seasonal effects for predicting accrual in clinical trials: Application to HOBIT and BOOST-3 trials for severe traumatic brain injury
DOI:10.1016/j.conctc.2025.101586 -
Gotthardt CJ, Barber JK, Eagle SR, van Essen TA, Nelson LD, Fu AY, Satris GG, Vreeburg RJG, Tracey JX, Etemad LL, Wong JC, Elguindy MM, Belton PJ, Madhok DY, Korley FK, Ferguson AR, Torres-Espin A, Duhaime A-C, Halabi C, Huang MC, Tarapore PE, DiGiorgio AM, Valadka AB, Robertson CS, Mukherjee P, Yuh EL, Puccio AM, Okonkwo DO, Giacino JT, McCrea MA, Temkin NR, Manley GT, Yue JK, TRACK-TBI Investigators . Pain, 2025 Nov 19;Journal ArticleLongitudinal pain intensity and interference symptomatology in mild traumatic brain injury: a TRACK-TBI study.
DOI:10.1097/j.pain.0000000000003869 PMID: 41734261 -
Beall J, Yeatts SD, Silbergleit R, Shutter L, Korley F, Gajewski B. Trials, 2025 Nov 10; 26 (1): 483Journal ArticleBayesian enrollment modeling for several emergency medicine clinical trials.
DOI:10.1186/s13063-025-08748-3 PMID: PMC12599014 -
Moll K, Sharpe Z, Harding L, Gomez C, Duckett Z, Greer N, Tiba M, Gherasim C, Korley F, Rees P, Price J, Hsu C. Circulation, 2025 Nov 6; 152 (Suppl_3): asat203 - asat203.Proceeding / Abstract / PosterAbstract Sat203: Rapid UCH-L1 and GFAP Brain Injury Biomarker Detection in Out-of-Hospital Cardiac Arrest: A Swine Model and Prehospital Feasibility Study
DOI:10.1161/circ.152.suppl_3.sat203
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