Eliza PS Tsou, PhD
Frederick G L Huetwell Research Professor of Rheumatology II
Assistant Professor of Internal Medicine
Assistant Professor of Pharmacology
Medical School
Office:
Michigan Medicine
Internal Medicine/Rheumatology
2800 Plymouth Road, Building 20, Room 1822
Ann Arbor, Michigan 48109
Internal Medicine/Rheumatology
2800 Plymouth Road, Building 20, Room 1822
Ann Arbor, Michigan 48109
Email:
[email protected]
Phone:
Available to mentor
Eliza PS Tsou, PhD
Assistant Professor
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Qualifications
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PhD, Department of Pharmaceutical Sciences. School of PharmacyUniversity at Buffalo, State University of New York, Buffalo, NY, United States
2002 - 2008
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BSc, Department of PharmacyNational Taiwan University, Taipei, Taiwan
1997 - 2001
Center Memberships
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberGlobal REACH
Recent Publications
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Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Nature Communications, 2024 Dec 1; 15 (1):Journal ArticleSystems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis
DOI:10.1038/s41467-023-44645-6 PMID: 38172207 -
van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. Journal of Clinical Investigation, 2024 Feb 10; 134 (3):Journal ArticleSingle-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa
DOI:10.1172/JCI169225 PMID: 38051587 -
Shi B, Tsou PS, Ma F, Mariani MP, Mattichak MN, LeBrasseur NK, Chini EN, Lafyatis R, Khanna D, Whitfield ML, Gudjonsson JE, Varga J. Journal of Investigative Dermatology, 2023 Apr 1; 143 (4): 661 - 664.e5.Journal ArticleSenescent Cells Accumulate in Systemic Sclerosis Skin
DOI:10.1016/j.jid.2022.09.652 PMID: 36191640 -
Ikari Y, Lu C, Rosek A, Cai A, Khanna N, St Clair J, Webber A, Foster C, Chen YC, Ali RA, Khanna D, Fox DA, Tsou PS. Arthritis Research and Therapy, 2026 Dec 1; 28 (1):Journal ArticleSoluble CD13 in systemic sclerosis: clinical observations and transcriptomic insights from peripheral blood
DOI:10.1186/s13075-025-03723-4 PMID: 41520101 -
Gurrea-Rubio M, Sloan S, Chada A, Amarista CI, Maeda K, Campbell PL, Tsou P-S, Cooney LA, Wicha MS, Fox DA. Biomolecules, 2026 Aug 19; 16 (8): 1202 - 1202.Journal ArticleCD6-Directed Immunotherapy Targets Breast Cancer Stem Cell Function and Enhances Immune-Mediated Cytotoxicity in Triple-Negative Breast Cancer
DOI:10.3390/biom16081202 -
Kataria S, Ikari Y, Rosek A, Kahnna N, Vichaikul S, Wu Q, Khanna D, Tsou P. Journal of Investigative Dermatology, 2026 Jul 22; 146 (8): s30Journal Article0170 CaMKII integrates calcium signaling and oxidative stress to promote fibrosis in scleroderma fibroblasts
DOI:10.1016/j.jid.2026.06.201 -
Verma P, Hamill T, Bale S, Shah K, Patel K, Dey P, Bajzelj M, Yalavarthi B, Tsou P, Gudjonsson JE, Khanna D, Varga J, Bhattacharyya S. Journal of Investigative Dermatology, 2026 Jul 22; 146 (8): s157Journal Article0908 Targeting histone acetyl transferase p300 for treating fibrosis and senescence: A new therapeutic approach
DOI:10.1016/j.jid.2026.06.939 -
Kaundal U, Tsou PS, Sahu M, Huang M, Boyden SE, Woodford CM, Shriner D, Stenson E, Safran SA, Zhou Y, Talley TA, Gudapati K, Zhang X, Kunishita Y, Wang J, Shah AA, Mayes MD, Doumatey AP, Bentley AR, Domsic R, Medsger TA, Ramos PS, Silver RM, Steen V, Varga J, Hsu V, Saketkoo LA, Schiopu E, Gordon JK, Criswell LA, Gladue H, Derk C, Bernstein EJ, Bridges SL, Shanmugam V, Chung L, Kafaja S, Jan R, Trojanowski M, Goldberg A, Korman BD, Mullikin J, Thomas JW, Dell'Orso S, Randazzo D, Adeyemo A, Remmers EF, Schwartzberg PL, Aksentijevich I, Rotimi C, Wigley FM, Wang RA, Boin F, Khanna D, Lafyatis R, Kastner DL, Gourh P. Annals of the Rheumatic Diseases, 2026 Jul 1; 85 (7): 1396 - 1412.Journal ArticleGain of function NOTCH4 variants disrupt angiogenesis in systemic sclerosis
DOI:10.1016/j.ard.2025.12.015 PMID: 41644364
Featured News & Stories
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Protein found in rheumatic diseases causes inflammation in COVID-19 patients
Research on the inflammatory mediator called sCD13 has identified this molecule and its receptors as new targets for treatment of autoimmune rheumatic diseases. The data suggests that sCD13 may also be of great importance in severe complications of COVID-19.
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Targeting and blocking sCD13 protein could lead to systemic sclerosis treatment
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