Kirk A Frey

portrait of Kirk Frey
David E Kuhl Legacy Professor of Radiology
Professor of Radiology
Professor of Neurology
Research Professor, Michigan Neuroscience Institute, Medical School
Email:
[email protected]
Available to mentor
Kirk A Frey
portrait of Kirk Frey
Professor
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  • Center Memberships

    • Center Member
      Samuel and Jean Frankel Cardiovascular Center

    Recent Publications

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    • Journal Article
      Comparison of imaging-based bone marrow dosimetry methodologies and their dose–effect relationships in [177Lu]Lu-PSMA-617 RLT including a novel method with active marrow localization
      Peterson AB, Wilderman SJ, Blakkisrud J, Wong KK, Frey KA, Dewaraja YK. Ejnmmi Physics, 2026 Dec 1; 13 (1): DOI:10.1186/s40658-025-00816-6
    • Journal Article
      Predicting [177Lu]Lu-PSMA-617 SPECT/CT-based absorbed dose to whole-body tumor volume from pre-therapy [68Ga]Ga-PSMA-11 PET metrics and common blood biomarkers
      Fitzpatrick KJ, Suresh K, Roseland ME, Niedbala J, Ngai K, Wong KK, Frey KA, Dewaraja YK. EJNMMI Physics, 2026 Sep 27; DOI:10.1186/s40658-026-00939-4
    • Journal Article
      Assessing PSMA Receptor Availability using Ga-68-PSMA-11 PET/CT Following Lu-177-PSMA-617 Therapy Administration
      Roseland M, Fitzpatrick K, Lu Z, Hillmer A, Wong KK, Viglianti B, Frey K, Dewaraja Y. Clinical Nuclear Medicine, 2025 Sep 22; 51 (4):
    • Journal Article
      CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression
      Coughlin DG, Jain L, Khrestian M, Bozoki AC, Galvin JE, Irwin DJ, Lippa CF, Litvan I, Pillai JA, Tousi B, Lopez OL, Berman S, Tsuang DW, Zabetian CP, Fleisher JE, Taylor AS, Leverenz JB, Bekris LM, Galasko D, Albin R, Alcalay R, Ascherio A, Beach T, Berman S, Boeve B, Bowman FDB, Chen S, Chen-Plotkin A, Dauer W, Dawson T, Desplats P, Dewey R, Dorsey R, Fleisher J, Frey K, Galvin J, German D, Gunzler S, Honig L, Huang X, Irwin D, Kantarci K, Kanthasamy A, Kaufer D, Kong Q, Leverenz J, Levey A, Lippa C, Litvan I, Lopez O, Ma J, Mangravite L, Marder K, Narayanan N, Orzelius L, Petyuk V, Potashkin J, Rosenthal L, Saunders-Pullman R, Scherzer C, Schwarzschild M, Seyfried N, Simuni T, Singleton A, Standaert D, Tsuang D, Vaillancourt D, Vitek J, Walt D, West A, Zabetian C, Zhang J. Neurology, 2025 Dec 23; 105 (12): DOI:10.1212/WNL.0000000000214346
      PMID: 41248454
    • Journal Article
      A multicenter longitudinal study of cholinergic subgroups in Parkinson disease
      Bohnen NI, Roytman S, van der Zee S, Carli G, Michalakis F, Luker A, Slingerland S, Frey KA, Scott PJH, Koeppe RA, van Laar T, Albin RL, Kanel P. Nature Communications, 2025 Dec 1; 16 (1): DOI:10.1038/s41467-025-60815-0
      PMID: 40593607
    • Journal Article
      IND-enabling preclinical studies of [11C]COU, a trapped metabolite PET radiotracer for monoamine oxidase-B
      Frazier MS, Kaur T, Stauff J, Winton WP, Henderson BD, Dumond AS, Shao X, Raffel DM, Frey KA, Kilbourn MR, Brooks AF, Scott PJH. Medicinal Chemistry Research, 2025 Dec 1; 34 (12): 2537 - 2546. DOI:10.1007/s00044-025-03496-0
    • Journal Article
      Posology for Lu-177-DOTATATE Therapy in Neuroendocrine Tumor: Effectiveness of Dose Reduction and Cycle Delay for Improving Therapy Tolerability
      Wang I, Patterson J, Akhavanallaf A, Lu Z, Viglianti B, Roseland M, Muhleman M, Frey K, Scott P, Dewaraja Y, Wong KK. Clinical Nuclear Medicine, 2025 Sep 22; 50 (12): 1144 - 1151.
    • Journal Article
      177Lu-PSMA-617 Single-Photon Emission Computed Tomography/Computed Tomography Dosimetry and Radiobiological Models Demonstrate Decreasing Tumor-to-Kidney Dose Ratio With Successive Cycles
      Fitzpatrick KJ, Mikell JK, Roseland ME, Niedbala J, Suresh K, Peterson AB, Viglianti BL, Wong KK, Frey KA, Dewaraja YK. International Journal of Radiation Oncology Biology Physics, 2025 Nov 15; 123 (4): 937 - 946. DOI:10.1016/j.ijrobp.2025.06.3869
      PMID: 40582602