Melvin G McInnis, MD, FRCPsych
Thomas B and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression
Professor of Psychiatry
Professor of Learning Health Sciences
Program Director of Bipolar Psychiatry
Medical School
Available to mentor
Melvin G McInnis, MD, FRCPsych
Professor
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Center Memberships
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberEisenberg Family Depression Center
Recent Publications
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Roberts G, Ratheesh A, Fullerton JM, Cignarella C, Francis E, Kamali M, Stapp EK, Ghaziuddin N, Hulvershorn L, McInnis MG, Wilcox HC, Edenberg HJ, Nurnberger JI, Mitchell PB. Journal of Affective Disorders, 2026 Nov 1; 412:Journal ArticleParental but not child reports of affective lability in offspring predict conversion to bipolar disorder in youth at increased genetic risk
DOI:10.1016/j.jad.2026.122077 -
Kim H, Yocum AK, McInnis MG, Sperry SH. J Affect Disord, 2026 Mar 23; 121671Journal ArticlePredicting suicidal ideation from depression screening data: A network-augmented machine learning approach.
DOI:10.1016/j.jad.2026.121671 PMID: 41881118 -
Wrobel AL, Dean OM, Lotfaliany M, Berk M, Sylvia LG, Thase ME, Deckersbach T, Tohen M, McInnis MG, Kocsis JH, Shelton RC, McElroy SL, Turner A, Nierenberg AA. Bipolar Disorders, 2026 Mar 1; 28 (2):Journal ArticlePotential Impact of Childhood Abuse on Quality of Life During Mood-Stabilising Treatment in Individuals Living With Bipolar Disorder
DOI:10.1111/bdi.70079 PMID: 41677164 -
Turner A, Kuperberg M, McGovern H, Wrobel A, Dean OM, Berk M, Sylvia L, McElroy SL, Tohen M, Shelton RC, Iosifescu DV, Thase ME, Kocsis JH, Ostacher MJ, Deckersbach T, McInnis MG, Köhler-Forsberg O, Nierenberg AA. Journal of Affective Disorders, 2026 Jan 15; 393:Journal ArticleAdverse childhood experiences and cardiometabolic risk factors in people with bipolar disorder
DOI:10.1016/j.jad.2025.120270 PMID: 40935250 -
Pandina G, DelBello MP, Rassnick S, Solanki B, Canuso CM, Fristad MA, Correll CU, Nurnberger JI, Singh MK, McInnis MG, Atkinson S, Stedman M, Goes FS, Strakowski SM, Greer TL, Nierenberg AA, Salvadore G, Drevets WC. Journal of Affective Disorders, 2026 Jan 15; 393:Journal ArticleClinical outcomes of youth at familial risk for bipolar disorder: A 2-year longitudinal, observational study
DOI:10.1016/j.jad.2025.120492 PMID: 41106637 -
Lipschitz JM, Adler C, Almeida JRC, Assari S, Bond DJ, Breitzig MT, DePaulo JR, El-Mallakh R, Fiedorowicz J, Freshley J, Fries GR, Frye MA, Goes FS, Gonzalez R, Huber R, Jamison K, Liu G, Machado-Vieira R, Mahon P, McInnis MG, Meyer TD, Youssef NA, Nurnberger JI, Ostacher M, Parikh SV, Pinjari O, Raj K, Respino M, Sanches M, Schneck CD, Singh MK, Soares JC, Strakowski SM, Sullivan A, Suppes T, Thase ME, Wang P, Waxmonsky JA, Yurgelun-Todd D, Zandi PP, Burdick KE. Journal of Affective Disorders, 2026 Jan 15; 393:Journal ArticleConsiderations in the development of learning health networks for mood disorders
DOI:10.1016/j.jad.2025.119904 PMID: 40652981 -
McInnis MG, DePaulo JR. Acta Psychiatrica Scandinavica, 2026 Jan 1; 153 (1): 3 - 5.Journal ArticleClinical Judgment and the Architecture of Reasoning in Psychiatry
DOI:10.1111/acps.70047 PMID: 41265865 -
Kraft JD, Suzuki T, Menkes MW, Andrews CM, McInnis MG, Deldin PJ, Tso IF. Clinical Neurophysiology, 2025 Dec 1; 180:Journal ArticleAttenuated theta-band activity and cross-frequency coupling in schizophrenia during affective response inhibition
DOI:10.1016/j.clinph.2025.2111386 PMID: 41124888
Featured News & Stories
Research News
Hidden Brain “Rethinking Depression”: Dr. Jonathan Rottenberg highlights Dr. Melvin McInnis
Cornell psychologist Jonathan Rottenberg, Ph.D., reflects on recovering from depression and reconnecting with Melvin McInnis, M.D., in Hidden Brain’s “Rethinking Depression.”
Research News
Clinical Judgment and the Architecture of Reasoning in Psychiatry
"Clinical Judgment and the Architecture of Reasoning in Psychiatry," editorial from Melvin McInnis, M.D., director of the Heinz C. Prechter Bipolar Research Program and Raymond DePaulo, M.D., Johns Hopkins University
Research News
New "Ask the Doctor" column written by Dr. Melvin McInnis for bpHope
New "Ask the Doctor" column written by Dr. Melvin McInnis for bpHope
Research News
A Letter from the Director
A letter from the Director of the Heinz C. Prechter Bipolar Research Program.
Philanthropy News
From seeking answers to fueling progress
Patricia and Jerry Wagner have provided ongoing, dedicated support to the Heinz C. Prechter Bipolar Research Program at University of Michigan Heatlh.
Research News
Prechter Program Director featured in WebMD article
Dr. Melvin McInnis discusses the latest treatments for bipolar disorder in a WebMD interview.