Melvin G McInnis, MD, FRCPsych
Thomas B and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression
Professor of Psychiatry
Professor of Learning Health Sciences
Program Director of Bipolar Psychiatry
Medical School
Available to mentor
Melvin G McInnis, MD, FRCPsych
Professor
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Center Memberships
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Center MemberCenter for Computational Medicine and Bioinformatics
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Center MemberEisenberg Family Depression Center
Recent Publications
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Kim H, Smith JL, McInnis MG, Sperry SH. Journal of Affective Disorders, 2026 Dec 1; 414:Journal ArticleBimonthly mood-suicidal ideation dynamics in bipolar spectrum disorders: A dynamic structural equation modeling study
DOI:10.1016/j.jad.2026.122334 PMID: 42521090 -
Roberts G, Ratheesh A, Fullerton JM, Cignarella C, Francis E, Kamali M, Stapp EK, Ghaziuddin N, Hulvershorn L, McInnis MG, Wilcox HC, Edenberg HJ, Nurnberger JI, Mitchell PB. Journal of Affective Disorders, 2026 Nov 1; 412:Journal ArticleParental but not child reports of affective lability in offspring predict conversion to bipolar disorder in youth at increased genetic risk
DOI:10.1016/j.jad.2026.122077 PMID: 42248532 -
Yocum AK, Alda M, Aouizerate B, Aubin V, Bellivier F, Belzeaux R, Berk M, Biernacka JM, Budde M, Burdick KE, Chang YH, Coombes BJ, Courtet P, Dalkner N, Diaz-Byrd C, Dubertret C, Etain B, Fico G, Fullerton JM, Godin O, Gordon-Smith K, Haffen E, Januel D, Keramatian K, Leboyer M, Lefrere A, Llorca PM, Majd M, Mitchell PB, Mwangi B, Olie E, Overs BJ, Petite J, Polosan M, Rey R, Roberts G, Roux P, Samalin L, Schwan R, Serretti A, Soares JC, Sperry SH, Strawbridge R, Stross T, Vieta E, Walter M, Williams LJ, Wu MJ, Yatham LN, Young AH, Yrondi A, Zunta-Soares GB, Frye MA, McInnis MG, Singh B. Bipolar Disorders, 2026 Sep 1; 28 (6): e70167Journal ArticlePrescription Trends for Bipolar Disorder With and Without Comorbid Substance Use and Anxiety Disorders: A Global Bipolar Cohort Collaborative Study
DOI:10.1111/bdi.70167 PMID: 42578538 -
Kraft JD, Locarno L, Suzuki T, Riddle J, Chang SE, McInnis MG, Fröhlich F, Taylor SF, Tso IF. Bipolar Disorders, 2026 Aug 1; 28 (5):Journal ArticleEnhancing Affective Cognitive Control in Bipolar Disorder Using Transcranial Alternating Current Stimulation: A Double-Blind, Randomized, Sham-Controlled Clinical Trial and Proof of Concept Study
DOI:10.1111/bdi.70142 PMID: 42381254 -
Schneck CD, Almeida JRC, Bond DJ, Burdick KE, Frye MA, Goes FS, Huber RS, Machado-Vieira R, Mahon P, McInnis MG, Nurnberger J, Ongur D, Ostacher MJ, Parikh SV, Raj KS, Respino M, Schweizer BW, Soares JC, Sperry SH, Sullivan AE, Suppes T, Veldic M, Zandi PP, DePaulo JR. Bipolar Disorders, 2026 Aug 1; 28 (5):Journal ArticleEstablishing a Specialty Bipolar Clinic: The National Network of Depression Centers Consensus Recommendations
DOI:10.1111/bdi.70154 PMID: 42429592 -
Kim H, Yocum AK, McInnis MG, Sperry SH. Journal of Affective Disorders, 2026 Aug 1; 406:Journal ArticlePredicting suicidal ideation from depression screening data: A network-augmented machine learning approach
DOI:10.1016/j.jad.2026.121671 PMID: 41881118 -
Wrobel AL, Dean OM, Lotfaliany M, Berk M, Sylvia LG, Thase ME, Deckersbach T, Tohen M, McInnis MG, Kocsis JH, Shelton RC, McElroy SL, Turner A, Nierenberg AA. Bipolar Disorders, 2026 Mar 1; 28 (2):Journal ArticlePotential Impact of Childhood Abuse on Quality of Life During Mood-Stabilising Treatment in Individuals Living With Bipolar Disorder
DOI:10.1111/bdi.70079 PMID: 41677164 -
Turner A, Kuperberg M, McGovern H, Wrobel A, Dean OM, Berk M, Sylvia L, McElroy SL, Tohen M, Shelton RC, Iosifescu DV, Thase ME, Kocsis JH, Ostacher MJ, Deckersbach T, McInnis MG, Köhler-Forsberg O, Nierenberg AA. Journal of Affective Disorders, 2026 Jan 15; 393:Journal ArticleAdverse childhood experiences and cardiometabolic risk factors in people with bipolar disorder
DOI:10.1016/j.jad.2025.120270 PMID: 40935250
Featured News & Stories
Research News
Differences on how doctors prescribe for bipolar disorder around the world
A global study of 11,521 people reveals how anxiety and substance use disorders affect bipolar medication patterns globally.
Research News
Hidden Brain “Rethinking Depression”: Dr. Jonathan Rottenberg highlights Dr. Melvin McInnis
Cornell psychologist Jonathan Rottenberg, Ph.D., reflects on recovering from depression and reconnecting with Melvin McInnis, M.D., in Hidden Brain’s “Rethinking Depression.”
Research News
Clinical Judgment and the Architecture of Reasoning in Psychiatry
"Clinical Judgment and the Architecture of Reasoning in Psychiatry," editorial from Melvin McInnis, M.D., director of the Heinz C. Prechter Bipolar Research Program and Raymond DePaulo, M.D., Johns Hopkins University
Research News
New "Ask the Doctor" column written by Dr. Melvin McInnis for bpHope
New "Ask the Doctor" column written by Dr. Melvin McInnis for bpHope
Research News
A Letter from the Director
A letter from the Director of the Heinz C. Prechter Bipolar Research Program.
Philanthropy News
From seeking answers to fueling progress
Patricia and Jerry Wagner have provided ongoing, dedicated support to the Heinz C. Prechter Bipolar Research Program at University of Michigan Heatlh.
